Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 62391434

GI number: 62391434

Start: 2732837

End: 2734957

Strand: Reverse

Name: ptrB [H]

Synonym: cg2873

Alternate gene names: 62391434

Gene position: 2734957-2732837 (Counterclockwise)

Preceding gene: 62391435

Following gene: 62391433

Centisome position: 83.31

GC content: 55.16

Gene sequence:

>2121_bases
ATGTCTGAACGCCTAAACGCTCCGCAAGCACCAATCCATCCCATCACCCGAACCCACCACGGTATTGATTTCGTAGACAA
CTATGAATGGCTGAGGGATAAAGAATCCCAAGAAACCTTGGACTACCTGGAGGCGGAGAATGCGTTCACCAAGCAGGAGA
CTGAACAGCTAGCCACACTGCGGGACAACATCTATGAAGAGATTAAGTCACGCGTTAAAGAAACCGACATGTCCATCCCA
GTGCGTGCCGGAAAGCACTGGTATTACTCTCGCACTGAAGAAGGCAAGAGCTACGGCTATTCCTGCCGCATTCCAGTGAC
TGAAGGGTCGGATGCATGGACCCCTCCTGTTATCCCTGAGGGTGAGCCAGCGCAGGGTGAAACCATCATCATGGATGCCA
ACGAGTTGGCAGAAGGCCACGAATTCTTCTCCATGGGTGCATCATCTGTCACCACCTCTGGCCGCTACCTTGCGTATTCC
ACCGATGTCACGGGCGAAGAGCGCTTTACGTTGCGCATCAAGGATCTAGAAACTGGCGAGCTGCTTCCTGATACCCTGAC
TGGCATTTTCTACGGTGCTACTTGGGTGGGGGAGGAGTACCTCTTTTACCAGCGCGTTGATGATGCGTGGCGTCCAGATA
CTGTGTGGCGCCACAAGGTGGGTACCCCGGTTGAAGAAGACGTGTTGGTGTACCACGAGCCTGATGAACGTTATTCCACC
TGGGTGGGCACCACTCGTTCAGAAAAGTTCATCCTTTTTGGTTGCGCCTCCAAGATCACCTCTGAAGTCCGCGTGCTTCC
TTTCGACCAGCCAGAGGGCACCCCTGAGGTGCTGATTCCGCGCGCGGAGGGTGTGGAATACGACGTCGATCATGCAGTCG
TAGACGGCTCCGATATTTGGTTGGTCACACACAACGCCGAGGGCCCGAACTTTTCGGTGGGGTGGGCTGGCGTCGACAAG
CTCAATTCTTTGGACGCGCTGGCGCCACTCGTCGCGCACAAGGATGACGTGCGCATTGAGGGTGTCGATACCTACCGCGA
TTTCATCATCCTGGGCTACAGGTCCGGCGCGATCGGCCAGGTCGCGATCATGAAGCTTATCGACGGAACCTTCGGCGATT
TCCAACAGCTGGAATTTGACGAGGAAATCTACACCGTCGCATCGGGCGGAAACCCAGAATGGGACGCCCCCGTCATTCGC
CTTTCTTACGGATCATTCACCACCCCGGCGCAGCTGTTTAACTACTGGATTGAATCCGGCGAACGCACGCTGCTGAAGCA
GCAGGAAGTGCTCGGCGGATACAAGCCGTCAGACTATGTGGCCTCCCGATTGTGGGTCACTGCGAAAGATGGCGCGCAGA
TTCCAGTGTCCTTGGTGCACCGCACCGACCTGGATGTATCCAAGCCCAACCCCACGTTGCTCTACGGCTATGGTTCCTAC
GAATCATCCATTGATCCAGGCTTCTCTATCGCGCGTTTGTCACTGATGGATCGTGGCATGATTTTTGCGATTGCCCACGT
TCGTGGCGGTGGCGAAATGGGTCGTGGCTGGTACGACAACGGCAAAACCACCACGAAGAAAAACACCTTCACCGACTTCA
TTGATGTTGCCGACGCCCTCATCGAGCAGAAGATTTCTGCCCCTGAAATGCTGGTTGCAGAAGGCGGCTCAGCTGGTGGC
ATGCTCATGGGCGCCATTGCCAACATGGCCGGTGACCGCTTCAAGGCGATCGAAGCCAACGTGCCATTCGTCGATCCGCT
GACCTCTATGCTCATGCCGGAACTGCCACTGACGGTTATCGAATGGGATGAGTGGGGCGATCCACTCCACGATAAGGACG
TCTATGAATACATGGCGTCGTATGCCCCATATGAAAACATCGAGGCAAAGAACTACCCCAATATCTTGGCCGTAACATCG
CTCAACGACACCCGAGTGTTGTACGTCGAACCAGCCAAATGGGTAGCGCAGCTTCGGGCGACTGCAACCGGTGGAGAATT
CCTTCTGAAAACTGAAATGGTTGCCGGACACGGCGGTGTGTCAGGACGCTACGAAAAGTGGCGTGAGACTGCATTTGAGT
ACGGCTGGTTGATCAACCAAGCAACCGGTGTGACCGAATAA

Upstream 100 bases:

>100_bases
AAATGAATCCGGGTTTTTCAGTTTCGGGGTGCAAATCAGAATGTCGCCAATGGCGAACACACGAGCGTGCAGAAGATGTG
CGTGACTAAGATCGGGGGCT

Downstream 100 bases:

>100_bases
AACTTGTTCGACTAGCGAACTTTAAATCACCCTCGGCGACTTTAGCGGGGGTGATTTATTCTTTTTCGGGGGGTTTGGGT
ACGAGCGGAGAAATTTGGGC

Product: prolyl oligopeptidase

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MSERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATLRDNIYEEIKSRVKETDMSIP
VRAGKHWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPEGEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYS
TDVTGEERFTLRIKDLETGELLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIWLVTHNAEGPNFSVGWAGVDK
LNSLDALAPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQVAIMKLIDGTFGDFQQLEFDEEIYTVASGGNPEWDAPVIR
LSYGSFTTPAQLFNYWIESGERTLLKQQEVLGGYKPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPTLLYGYGSY
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADALIEQKISAPEMLVAEGGSAGG
MLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVIEWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTS
LNDTRVLYVEPAKWVAQLRATATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE

Sequences:

>Translated_706_residues
MSERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATLRDNIYEEIKSRVKETDMSIP
VRAGKHWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPEGEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYS
TDVTGEERFTLRIKDLETGELLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIWLVTHNAEGPNFSVGWAGVDK
LNSLDALAPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQVAIMKLIDGTFGDFQQLEFDEEIYTVASGGNPEWDAPVIR
LSYGSFTTPAQLFNYWIESGERTLLKQQEVLGGYKPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPTLLYGYGSY
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADALIEQKISAPEMLVAEGGSAGG
MLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVIEWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTS
LNDTRVLYVEPAKWVAQLRATATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE
>Mature_705_residues
SERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATLRDNIYEEIKSRVKETDMSIPV
RAGKHWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPEGEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYST
DVTGEERFTLRIKDLETGELLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYSTW
VGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIWLVTHNAEGPNFSVGWAGVDKL
NSLDALAPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQVAIMKLIDGTFGDFQQLEFDEEIYTVASGGNPEWDAPVIRL
SYGSFTTPAQLFNYWIESGERTLLKQQEVLGGYKPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPTLLYGYGSYE
SSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADALIEQKISAPEMLVAEGGSAGGM
LMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVIEWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTSL
NDTRVLYVEPAKWVAQLRATATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=705, Percent_Identity=25.531914893617, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI284172438, Length=453, Percent_Identity=27.8145695364238, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI284172431, Length=453, Percent_Identity=27.8145695364238, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI284172420, Length=465, Percent_Identity=27.9569892473118, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI284172413, Length=465, Percent_Identity=27.9569892473118, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI70778815, Length=465, Percent_Identity=27.9569892473118, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI108860686, Length=204, Percent_Identity=37.2549019607843, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI108860692, Length=200, Percent_Identity=37, Blast_Score=131, Evalue=2e-30,
Organism=Escherichia coli, GI1788150, Length=702, Percent_Identity=36.7521367521368, Blast_Score=455, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24583414, Length=727, Percent_Identity=26.2723521320495, Blast_Score=204, Evalue=3e-52,
Organism=Drosophila melanogaster, GI221510989, Length=711, Percent_Identity=24.0506329113924, Blast_Score=172, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78921; Mature: 78790

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATL
CCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
RDNIYEEIKSRVKETDMSIPVRAGKHWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPE
HHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCC
GEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYSTDVTGEERFTLRIKDLETGE
CCCCCCCEEEEECHHHHCCHHHHHCCCCCEECCCEEEEEECCCCCCCEEEEEEEECCCCC
LLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
CCHHHHHHHHHCHHHCCCHHHEEEHHCCCCCCCCHHHHCCCCCCCCCEEEEECCCCHHHH
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIW
HCCCCCCCEEEEEECCHHHCCCEEEEECCCCCCCCCEEEECCCCCEEECCEEEECCCEEE
LVTHNAEGPNFSVGWAGVDKLNSLDALAPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQ
EEEECCCCCCEEECCCCHHHHCHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCCHH
VAIMKLIDGTFGDFQQLEFDEEIYTVASGGNPEWDAPVIRLSYGSFTTPAQLFNYWIESG
HHHHHHHCCCCCCHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
ERTLLKQQEVLGGYKPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPTLLYGYGSY
CHHHHHHHHHHCCCCCHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCC
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADAL
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
IEQKISAPEMLVAEGGSAGGMLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVI
HHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCEEEE
EWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTSLNDTRVLYVEPAKWVAQLRA
EECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHH
TATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE
CCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure 
SERLNAPQAPIHPITRTHHGIDFVDNYEWLRDKESQETLDYLEAENAFTKQETEQLATL
CCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
RDNIYEEIKSRVKETDMSIPVRAGKHWYYSRTEEGKSYGYSCRIPVTEGSDAWTPPVIPE
HHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCC
GEPAQGETIIMDANELAEGHEFFSMGASSVTTSGRYLAYSTDVTGEERFTLRIKDLETGE
CCCCCCCEEEEECHHHHCCHHHHHCCCCCEECCCEEEEEECCCCCCCEEEEEEEECCCCC
LLPDTLTGIFYGATWVGEEYLFYQRVDDAWRPDTVWRHKVGTPVEEDVLVYHEPDERYST
CCHHHHHHHHHCHHHCCCHHHEEEHHCCCCCCCCHHHHCCCCCCCCCEEEEECCCCHHHH
WVGTTRSEKFILFGCASKITSEVRVLPFDQPEGTPEVLIPRAEGVEYDVDHAVVDGSDIW
HCCCCCCCEEEEEECCHHHCCCEEEEECCCCCCCCCEEEECCCCCEEECCEEEECCCEEE
LVTHNAEGPNFSVGWAGVDKLNSLDALAPLVAHKDDVRIEGVDTYRDFIILGYRSGAIGQ
EEEECCCCCCEEECCCCHHHHCHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCCHH
VAIMKLIDGTFGDFQQLEFDEEIYTVASGGNPEWDAPVIRLSYGSFTTPAQLFNYWIESG
HHHHHHHCCCCCCHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
ERTLLKQQEVLGGYKPSDYVASRLWVTAKDGAQIPVSLVHRTDLDVSKPNPTLLYGYGSY
CHHHHHHHHHHCCCCCHHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCC
ESSIDPGFSIARLSLMDRGMIFAIAHVRGGGEMGRGWYDNGKTTTKKNTFTDFIDVADAL
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
IEQKISAPEMLVAEGGSAGGMLMGAIANMAGDRFKAIEANVPFVDPLTSMLMPELPLTVI
HHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCEEEE
EWDEWGDPLHDKDVYEYMASYAPYENIEAKNYPNILAVTSLNDTRVLYVEPAKWVAQLRA
EECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHH
TATGGEFLLKTEMVAGHGGVSGRYEKWRETAFEYGWLINQATGVTE
CCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]