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The map label for this gene is glsK

Identifier: 62391320

GI number: 62391320

Start: 2598164

End: 2599405

Strand: Reverse

Name: glsK

Synonym: cg2728

Alternate gene names: 62391320

Gene position: 2599405-2598164 (Counterclockwise)

Preceding gene: 62391327

Following gene: 62391319

Centisome position: 79.18

GC content: 58.29

Gene sequence:

>1242_bases
ATGTTGACGATGCCGATACCCGAGTACCTGCACGAAATTTTAGATGATGTCCGCGACACCACCTCCGGCGAGTTGGCCGA
TTACATCCCGGAACTAAAATCTGCGGACCCAAACCCGCTGGCAGTAGCCCTGTGCACCGTTAACGGACACATCTACAGCG
CAGGCGATGACGACATCGAATTCACCATGCAAAGTATTTCCAAGCCATTTGCCTACGCACTCGCACTCCAAGAATGCGGC
TTTGATGAGGTCTCTGCATCCGTGGCCTTGGAGCCCTCCGGTGAGGCCTTCAACGAACTTTCCCTCGACGGCGAAAACCG
CCCCATGAACCCCATGATCAACGCCGGCGCGATCGCCATCAACCAGCTGATCAACGGCTCCGATTCCACCGTGGAAGACC
GCGTGGAAAAAATCCGACACTACTTCTCTGAACTTGCTGGACGCGAACTCACCATCGACCGCGTGCTTGCCGAATCCGAA
CTCGCCGGCGCCGACCGCAACCTCTCCATCGCCCACATGCTGCGCAATTACGGCGTCATCGAAGACGAAGCCCACGACGC
CGTCCTCAGCTACACGCTGCAATGCGCCATCAAAGTAACCACGCGCGACCTCGCAGTCATGACCGCCACGCTCGCCGCCG
GCGGCACACACCCAATTACCGGCAAGAAGCTTCTCGACGCCCGCGTCTGCCGCCTCACCCTCTCCGTCATGGCTTCAGCA
GGCATGTACGACGAGGCAGGGCAGTGGCTCTCCACCGTAGGCATCCCCGCGAAATCAGGAGTCGCCGGCGGACTCATCGG
CATTCTGCCAGGTCAGCTGGGCATCGCCACATTTTCCCCACGCCTGAACCCCAAAGGCAACAGCGTGCGCGGCGTAAAAA
TATTCAAACAGCTTTCCGACGACATGGGCCTCCACCTCATGTCCACCGAGCAGGTATCCGGCCACGCAGTACGATCCATC
ACGCGGGACGGCGACACCACCTTCATCCAAATGCAGGGCGCCATGAACTTCTCCGCCAGCGAAAGCTTCCTCCACGCCAT
CGTGGAACACAACTTTGAAGGCACCGAAGTTGTTCTTGATCTCACCCGAGTACTTAGCTTCCACCCCGTAGCCATCCGCA
TGATCAAAGAAGGCCTCAAACGCATCCGCGACGCAGGCTTTGAGGTGTTCATCCTCGACCCAGATGACGTACTGCCCGAT
TTCATGTTTTCCGACGGCACCATCTGCAAAGAACGAGTGTGA

Upstream 100 bases:

>100_bases
TTTGCGACATCATAAATGGTGGCTTTTGAGTCGCTGTGAGCCCCAGAATCTGTCATGCACAAGAGTATATAGCGCAAAAG
AAATCACTAGTCTTGATTCT

Downstream 100 bases:

>100_bases
CCGGTAGCTTTATGGGCTGAACAATTCTAAGGAGAATTATCCGTGAAAAAGAAGCTTATGTTGCCTTTGATTGTTGCAGC
TTTGGGGTTAAGTGCCTGCA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MLTMPIPEYLHEILDDVRDTTSGELADYIPELKSADPNPLAVALCTVNGHIYSAGDDDIEFTMQSISKPFAYALALQECG
FDEVSASVALEPSGEAFNELSLDGENRPMNPMINAGAIAINQLINGSDSTVEDRVEKIRHYFSELAGRELTIDRVLAESE
LAGADRNLSIAHMLRNYGVIEDEAHDAVLSYTLQCAIKVTTRDLAVMTATLAAGGTHPITGKKLLDARVCRLTLSVMASA
GMYDEAGQWLSTVGIPAKSGVAGGLIGILPGQLGIATFSPRLNPKGNSVRGVKIFKQLSDDMGLHLMSTEQVSGHAVRSI
TRDGDTTFIQMQGAMNFSASESFLHAIVEHNFEGTEVVLDLTRVLSFHPVAIRMIKEGLKRIRDAGFEVFILDPDDVLPD
FMFSDGTICKERV

Sequences:

>Translated_413_residues
MLTMPIPEYLHEILDDVRDTTSGELADYIPELKSADPNPLAVALCTVNGHIYSAGDDDIEFTMQSISKPFAYALALQECG
FDEVSASVALEPSGEAFNELSLDGENRPMNPMINAGAIAINQLINGSDSTVEDRVEKIRHYFSELAGRELTIDRVLAESE
LAGADRNLSIAHMLRNYGVIEDEAHDAVLSYTLQCAIKVTTRDLAVMTATLAAGGTHPITGKKLLDARVCRLTLSVMASA
GMYDEAGQWLSTVGIPAKSGVAGGLIGILPGQLGIATFSPRLNPKGNSVRGVKIFKQLSDDMGLHLMSTEQVSGHAVRSI
TRDGDTTFIQMQGAMNFSASESFLHAIVEHNFEGTEVVLDLTRVLSFHPVAIRMIKEGLKRIRDAGFEVFILDPDDVLPD
FMFSDGTICKERV
>Mature_413_residues
MLTMPIPEYLHEILDDVRDTTSGELADYIPELKSADPNPLAVALCTVNGHIYSAGDDDIEFTMQSISKPFAYALALQECG
FDEVSASVALEPSGEAFNELSLDGENRPMNPMINAGAIAINQLINGSDSTVEDRVEKIRHYFSELAGRELTIDRVLAESE
LAGADRNLSIAHMLRNYGVIEDEAHDAVLSYTLQCAIKVTTRDLAVMTATLAAGGTHPITGKKLLDARVCRLTLSVMASA
GMYDEAGQWLSTVGIPAKSGVAGGLIGILPGQLGIATFSPRLNPKGNSVRGVKIFKQLSDDMGLHLMSTEQVSGHAVRSI
TRDGDTTFIQMQGAMNFSASESFLHAIVEHNFEGTEVVLDLTRVLSFHPVAIRMIKEGLKRIRDAGFEVFILDPDDVLPD
FMFSDGTICKERV

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain

Homologues:

Organism=Homo sapiens, GI156104878, Length=306, Percent_Identity=37.5816993464052, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI20336214, Length=300, Percent_Identity=38, Blast_Score=208, Evalue=8e-54,
Organism=Escherichia coli, GI1786693, Length=288, Percent_Identity=39.9305555555556, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1787804, Length=297, Percent_Identity=34.3434343434343, Blast_Score=180, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17507019, Length=356, Percent_Identity=37.6404494382022, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17532727, Length=312, Percent_Identity=40.0641025641026, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI193204073, Length=314, Percent_Identity=38.2165605095541, Blast_Score=217, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI193204075, Length=316, Percent_Identity=37.9746835443038, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281363241, Length=356, Percent_Identity=33.9887640449438, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI24653164, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24653162, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI281363239, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24653166, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24653156, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24653158, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI116008307, Length=356, Percent_Identity=33.9887640449438, Blast_Score=210, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_CORGL (Q8NMT3)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927155
- RefSeq:   NP_601682.1
- RefSeq:   YP_226722.1
- ProteinModelPortal:   Q8NMT3
- SMR:   Q8NMT3
- GeneID:   1020428
- GeneID:   3342801
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2728
- KEGG:   cgl:NCgl2395
- HOGENOM:   HBG512335
- OMA:   LLENDHP
- PhylomeDB:   Q8NMT3
- ProtClustDB:   PRK00971
- BioCyc:   CGLU196627:CG2728-MONOMER
- BRENDA:   3.5.1.2
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- InterPro:   IPR002645
- Gene3D:   G3DSA:3.40.710.20
- Gene3D:   G3DSA:3.30.750.24
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold; SSF52091 STAS

EC number: =3.5.1.2

Molecular weight: Translated: 44748; Mature: 44748

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTMPIPEYLHEILDDVRDTTSGELADYIPELKSADPNPLAVALCTVNGHIYSAGDDDIE
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCEEEECCCCHHH
FTMQSISKPFAYALALQECGFDEVSASVALEPSGEAFNELSLDGENRPMNPMINAGAIAI
HHHHHHCCHHHHHHHHHHCCCCHHCCEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHH
NQLINGSDSTVEDRVEKIRHYFSELAGRELTIDRVLAESELAGADRNLSIAHMLRNYGVI
HHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
EDEAHDAVLSYTLQCAIKVTTRDLAVMTATLAAGGTHPITGKKLLDARVCRLTLSVMASA
CCCHHHHHHHEEEEEEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GMYDEAGQWLSTVGIPAKSGVAGGLIGILPGQLGIATFSPRLNPKGNSVRGVKIFKQLSD
CCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
DMGLHLMSTEQVSGHAVRSITRDGDTTFIQMQGAMNFSASESFLHAIVEHNFEGTEVVLD
HCCEEEEECCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHH
LTRVLSFHPVAIRMIKEGLKRIRDAGFEVFILDPDDVLPDFMFSDGTICKERV
HHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MLTMPIPEYLHEILDDVRDTTSGELADYIPELKSADPNPLAVALCTVNGHIYSAGDDDIE
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCEEEECCCCHHH
FTMQSISKPFAYALALQECGFDEVSASVALEPSGEAFNELSLDGENRPMNPMINAGAIAI
HHHHHHCCHHHHHHHHHHCCCCHHCCEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHH
NQLINGSDSTVEDRVEKIRHYFSELAGRELTIDRVLAESELAGADRNLSIAHMLRNYGVI
HHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
EDEAHDAVLSYTLQCAIKVTTRDLAVMTATLAAGGTHPITGKKLLDARVCRLTLSVMASA
CCCHHHHHHHEEEEEEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GMYDEAGQWLSTVGIPAKSGVAGGLIGILPGQLGIATFSPRLNPKGNSVRGVKIFKQLSD
CCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
DMGLHLMSTEQVSGHAVRSITRDGDTTFIQMQGAMNFSASESFLHAIVEHNFEGTEVVLD
HCCEEEEECCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHH
LTRVLSFHPVAIRMIKEGLKRIRDAGFEVFILDPDDVLPDFMFSDGTICKERV
HHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626