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The map label for this gene is dppA [H]

Identifier: 62391279

GI number: 62391279

Start: 2552384

End: 2554093

Strand: Reverse

Name: dppA [H]

Synonym: cg2678

Alternate gene names: 62391279

Gene position: 2554093-2552384 (Counterclockwise)

Preceding gene: 62391284

Following gene: 62391278

Centisome position: 77.8

GC content: 55.67

Gene sequence:

>1710_bases
GTGTTTAAAAAGCACAGACACGGTCTCGGCTCCCCCGAAACCAAACCACGCTCAATAACCCGCCGGTTTTTCACCGCGGC
CGCCGCTACGCTGGCAGGATTGGCAGTCCTGTCCGGCTGCACAGCACAACCCTCACAAGCAGAAGACAACACGCTCACTT
ACTTAGAGCCACAGTTCTTCCGCACCCTGTACCCACCATCAGCGGGCTTTTACCCCAACGGCAGTGTGGTGAACAACATT
GCAGACCGCTTGCTCTACCAGGATCCTGAAACCTTGGAACTCAAGCCGTGGATCGCCACCGAACTCCCAGAAGTAAACGA
AGACGCCACGGAATTTACCTTCAACATCCGCACCGATGTCACCTACTCCGATGGCACCCCGCTGACGGCTGAAAACGTGG
TGAAAAACTTCGATCTCTATGGCCTCGGCGATCAAGATCGACGCCTCACCATCTCTGAGCAGATCACCAACTACGACCAC
GGCGAAGTAGTAGATGAGGACACCGTCCGATTCCACTTCTCTGAGCCTGCACCTGGTTTTGCTCAGGCCACCAGCTCCTT
CAACGCTGGCCTTTATGCCGATTCCACCTTGGAGTTCGCCAATGAGGATTTCGCCCCAGGCAACGCCCAAAACGTCATCG
GCTCCGGTCCTTTCGTGATCACCGATGAAACCCTAGGCACCAACCTCACCTTGACTGCGCGTGAGGATTACGATTGGGCA
CCACCATCACGCGAACATCAAGGTCGCGCGAAGCTTGACGCCGTCAATTATGTCCTCGCGGGTGAAGAATCCGTCCGCAT
CGGAGCCATCGTTGCTGGCCAAGGTGATATCGCCCGCCAGATCGAAGCGCCAGTGGAGGCACACCTGAAGGATGCAGGCA
TCCCGATCATCTCCGCAGCCACCAACGGTGTGAACAACAGCTTCAACTTCCGCTTCAAAAACGAGCTGCTCTCAGACATC
CGTGTTCGCCAAGCTCTGATCCACGCGATCGACCGCGAAAAGATCATGCGTGTGCTGTTTAGTGATTCCTATCCGCTGGC
AACTTCTGTGCTTGCGCAAAATGCACTGGGCTACAAAGAACAAGTAGATGCCTATGTCTACGACCTAGACAAAGCAACAG
CTCTGCTTGACGAAGCCGGCTGGACCCTTGATAGCGACGGCATGCGTCGCAAGGACGGTGAACTTCTAGAGCTCACCTTC
AACGAAGCCCTCCCACAGCCTCGTTCACGCGAAGTTGTCACCATGGTCCAAGAACAGCTCGGTGATCTGGGCATCAAGGT
CAACCTCAACCCAGGTGACCAAGCAGCCCAGGACGCTGACTCCAAGGATCTCAACAAGATCCAGGTTCGCCACACCATGG
TGGGTCGCGCAGACTATGACGTGCTGAAATCCCAGCTGTACTCCACCAACCGCAACGAGCTGTTGAACATGACCGTGGAA
GGGGAGACCGCCGATATTGGCGATCCTCATTTGGAGGAACTCCTCATGGCTATTGCATCCAGCCCACGCGAAGAGGACCG
TGCAGCAGCATCTGCCGCAGCACAGGATTACATCACCGAGCAGGCATATGTTCTTCCACTGTTTGAAGAGCCAGTTGTCT
ACGGCGTGCAGCCTTACGTGAAGGGCTTTAGCCCCGAAGTGATCGGCCGCCCCAGCTTCTATGAGACCTACATTGACCAT
TCCAGCGACCATTCCAGTGAGGAGGACTAA

Upstream 100 bases:

>100_bases
TCTGAACCAATATACCGATCAGTCTAAAAGTGTGTTAAGTTCTGGAACATAAATTAGCTGACACGTAAAGTAACTTAAAG
ATTCACTGGAGGTAAGCCTA

Downstream 100 bases:

>100_bases
ATGACTACCTCGCAGATTCTGCGCCGCATCGGCCAAGCCGTCTTGGTCTTGTTGGTCACCTTTACCTTGGCGTTCATCAT
GCTTTCCGCCCTCCCTGGCG

Product: ABC-type dipeptide/oligopeptide/nickel transport systems, component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MFKKHRHGLGSPETKPRSITRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFFRTLYPPSAGFYPNGSVVNNI
ADRLLYQDPETLELKPWIATELPEVNEDATEFTFNIRTDVTYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDH
GEVVDEDTVRFHFSEPAPGFAQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAATNGVNNSFNFRFKNELLSDI
RVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKEQVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTF
NEALPQPRSREVVTMVQEQLGDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTVE
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYVKGFSPEVIGRPSFYETYIDH
SSDHSSEED

Sequences:

>Translated_569_residues
MFKKHRHGLGSPETKPRSITRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFFRTLYPPSAGFYPNGSVVNNI
ADRLLYQDPETLELKPWIATELPEVNEDATEFTFNIRTDVTYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDH
GEVVDEDTVRFHFSEPAPGFAQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAATNGVNNSFNFRFKNELLSDI
RVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKEQVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTF
NEALPQPRSREVVTMVQEQLGDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTVE
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYVKGFSPEVIGRPSFYETYIDH
SSDHSSEED
>Mature_569_residues
MFKKHRHGLGSPETKPRSITRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFFRTLYPPSAGFYPNGSVVNNI
ADRLLYQDPETLELKPWIATELPEVNEDATEFTFNIRTDVTYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDH
GEVVDEDTVRFHFSEPAPGFAQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAATNGVNNSFNFRFKNELLSDI
RVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKEQVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTF
NEALPQPRSREVVTMVQEQLGDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTVE
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYVKGFSPEVIGRPSFYETYIDH
SSDHSSEED

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=563, Percent_Identity=23.4458259325044, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787052, Length=450, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787762, Length=462, Percent_Identity=23.1601731601732, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62841; Mature: 62841

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKHRHGLGSPETKPRSITRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHH
RTLYPPSAGFYPNGSVVNNIADRLLYQDPETLELKPWIATELPEVNEDATEFTFNIRTDV
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHCCCCCCCCCCEEEEEEEEEE
TYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDHGEVVDEDTVRFHFSEPAPGF
EECCCCCCCHHHHHHCCCEEECCCCCCEEEHHHHHCCCCCCCCCCCCCEEEEECCCCCCH
AQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
HHHHCCCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCC
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAA
CCCCCCCCCCHHHHEEEEEECCCCEEEEEEEECCCHHHHHHHCCHHHHHHHCCCCEEEEC
TNGVNNSFNFRFKNELLSDIRVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKE
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
QVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTFNEALPQPRSREVVTMVQEQL
HHHHHEEEHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHH
GDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTVE
CCCCEEEECCCCCHHHCCCCCCCCHHEEEEHHHHCCCHHHHHHHHHHCCCCCCEEEEEEC
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCHHH
KGFSPEVIGRPSFYETYIDHSSDHSSEED
CCCCCCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFKKHRHGLGSPETKPRSITRRFFTAAAATLAGLAVLSGCTAQPSQAEDNTLTYLEPQFF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHH
RTLYPPSAGFYPNGSVVNNIADRLLYQDPETLELKPWIATELPEVNEDATEFTFNIRTDV
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHCCCCCCCCCCEEEEEEEEEE
TYSDGTPLTAENVVKNFDLYGLGDQDRRLTISEQITNYDHGEVVDEDTVRFHFSEPAPGF
EECCCCCCCHHHHHHCCCEEECCCCCCEEEHHHHHCCCCCCCCCCCCCEEEEECCCCCCH
AQATSSFNAGLYADSTLEFANEDFAPGNAQNVIGSGPFVITDETLGTNLTLTAREDYDWA
HHHHCCCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCC
PPSREHQGRAKLDAVNYVLAGEESVRIGAIVAGQGDIARQIEAPVEAHLKDAGIPIISAA
CCCCCCCCCCHHHHEEEEEECCCCEEEEEEEECCCHHHHHHHCCHHHHHHHCCCCEEEEC
TNGVNNSFNFRFKNELLSDIRVRQALIHAIDREKIMRVLFSDSYPLATSVLAQNALGYKE
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
QVDAYVYDLDKATALLDEAGWTLDSDGMRRKDGELLELTFNEALPQPRSREVVTMVQEQL
HHHHHEEEHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHH
GDLGIKVNLNPGDQAAQDADSKDLNKIQVRHTMVGRADYDVLKSQLYSTNRNELLNMTVE
CCCCEEEECCCCCHHHCCCCCCCCHHEEEEHHHHCCCHHHHHHHHHHCCCCCCEEEEEEC
GETADIGDPHLEELLMAIASSPREEDRAAASAAAQDYITEQAYVLPLFEEPVVYGVQPYV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCHHH
KGFSPEVIGRPSFYETYIDHSSDHSSEED
CCCCCCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]