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The map label for this gene is nadD [H]

Identifier: 62391195

GI number: 62391195

Start: 2464175

End: 2464855

Strand: Reverse

Name: nadD [H]

Synonym: cg2584

Alternate gene names: 62391195

Gene position: 2464855-2464175 (Counterclockwise)

Preceding gene: 62391196

Following gene: 62391194

Centisome position: 75.09

GC content: 52.57

Gene sequence:

>681_bases
GTGCGAACACTATACTGTCCACTCATGACTACAACGGTGAAACGCCGCGCTCGCATTGGCATCATGGGTGGCACATTTGA
CCCCATTCATAATGGTCACCTTGTGGCGGGCTCAGAGGTAGCGGATCGATTCGATCTTGATCTGGTGGTGTACGTTCCCA
CCGGACAGCCATGGCAAAAGGCGAACAAGAAAGTCAGCCCAGCGGAAGATCGTTACCTGATGACGGTGATCGCCACTGCC
TCTAATCCACGGTTTATGGTATCGCGGGTTGATATTGATCGGGGAGGGGATACTTACACGATCGATACCCTGCAAGATTT
GAGCAAGCAATACCCGGACGCCCAGCTGTACTTCATCACCGGTGCCGATGCACTGGCACAGATCGTGACGTGGCGCGATT
GGGAGAAAACCTTCGAACTTGCCCACTTCGTTGGAGTGACTCGACCCGGTTATGAATTGGATGGAAACATCATTCCGGAA
ATGCACCAAGATCGAGTCTCATTGGTGGATATCCCCGCCATGGCTATTTCCTCCACGGACTGCAGAGAACGCTCCAGCGA
AGAACGCCCTGTTTGGTATCTTGTCCCTGATGGCGTGGTGCAATACATTGCCAAACGCCAACTCTATCGACCTGAAGGAT
CCGATAAGGATATGGATCCCAAGGGCCAAAACCAAGCATAA

Upstream 100 bases:

>100_bases
CGTTACCACCCAACCGTGGGATGAGCAGATTTTTGACGAAGTCGCATCGTGGATTGAAGCTGCCTAAAAACTCGCGAGGA
CGCATGCTCAGCAAGGTGGT

Downstream 100 bases:

>100_bases
ATCTAGTCAAAAGTTTCAACTTCTTGCCAAAAGTAGGTGAATCACCCTGCTTCGTGGAAAACTGGGAAGGGTTGACGTTG
CGGAATCTCTCCGCAGCGTC

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRTLYCPLMTTTVKRRARIGIMGGTFDPIHNGHLVAGSEVADRFDLDLVVYVPTGQPWQKANKKVSPAEDRYLMTVIATA
SNPRFMVSRVDIDRGGDTYTIDTLQDLSKQYPDAQLYFITGADALAQIVTWRDWEKTFELAHFVGVTRPGYELDGNIIPE
MHQDRVSLVDIPAMAISSTDCRERSSEERPVWYLVPDGVVQYIAKRQLYRPEGSDKDMDPKGQNQA

Sequences:

>Translated_226_residues
MRTLYCPLMTTTVKRRARIGIMGGTFDPIHNGHLVAGSEVADRFDLDLVVYVPTGQPWQKANKKVSPAEDRYLMTVIATA
SNPRFMVSRVDIDRGGDTYTIDTLQDLSKQYPDAQLYFITGADALAQIVTWRDWEKTFELAHFVGVTRPGYELDGNIIPE
MHQDRVSLVDIPAMAISSTDCRERSSEERPVWYLVPDGVVQYIAKRQLYRPEGSDKDMDPKGQNQA
>Mature_226_residues
MRTLYCPLMTTTVKRRARIGIMGGTFDPIHNGHLVAGSEVADRFDLDLVVYVPTGQPWQKANKKVSPAEDRYLMTVIATA
SNPRFMVSRVDIDRGGDTYTIDTLQDLSKQYPDAQLYFITGADALAQIVTWRDWEKTFELAHFVGVTRPGYELDGNIIPE
MHQDRVSLVDIPAMAISSTDCRERSSEERPVWYLVPDGVVQYIAKRQLYRPEGSDKDMDPKGQNQA

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) [H]

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family [H]

Homologues:

Organism=Escherichia coli, GI1786858, Length=210, Percent_Identity=29.0476190476191, Blast_Score=98, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432 [H]

EC number: =2.7.7.18 [H]

Molecular weight: Translated: 25559; Mature: 25559

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLYCPLMTTTVKRRARIGIMGGTFDPIHNGHLVAGSEVADRFDLDLVVYVPTGQPWQK
CCEEECHHHHHHHHHHHEEEEECCCCCCCCCCEEEECCHHHHHCCCEEEEEECCCCCHHH
ANKKVSPAEDRYLMTVIATASNPRFMVSRVDIDRGGDTYTIDTLQDLSKQYPDAQLYFIT
HCCCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCEEEHHHHHHHHHHCCCCEEEEEE
GADALAQIVTWRDWEKTFELAHFVGVTRPGYELDGNIIPEMHQDRVSLVDIPAMAISSTD
CHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCEEEEECCHHEECCCC
CRERSSEERPVWYLVPDGVVQYIAKRQLYRPEGSDKDMDPKGQNQA
HHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTLYCPLMTTTVKRRARIGIMGGTFDPIHNGHLVAGSEVADRFDLDLVVYVPTGQPWQK
CCEEECHHHHHHHHHHHEEEEECCCCCCCCCCEEEECCHHHHHCCCEEEEEECCCCCHHH
ANKKVSPAEDRYLMTVIATASNPRFMVSRVDIDRGGDTYTIDTLQDLSKQYPDAQLYFIT
HCCCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCEEEHHHHHHHHHHCCCCEEEEEE
GADALAQIVTWRDWEKTFELAHFVGVTRPGYELDGNIIPEMHQDRVSLVDIPAMAISSTD
CHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCEEEEECCHHEECCCC
CRERSSEERPVWYLVPDGVVQYIAKRQLYRPEGSDKDMDPKGQNQA
HHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]