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The map label for this gene is aceB

Identifier: 62391172

GI number: 62391172

Start: 2439598

End: 2441817

Strand: Reverse

Name: aceB

Synonym: cg2559

Alternate gene names: 62391172

Gene position: 2441817-2439598 (Counterclockwise)

Preceding gene: 62391175

Following gene: 62391170

Centisome position: 74.38

GC content: 55.77

Gene sequence:

>2220_bases
ATGACTGAACAGGAACTGTTGTCTGCTCAGACTGCCGACAACGCTGGAACTGACAGCACCGAACGCGTTGACGCGGGCGG
AATGCAGGTTGCAAAAGTTCTCTACGACTTTGTAACCGAAGCGGTACTCCCTCGCGTGGGTGTGGATGCGGAAAAGTTCT
GGTCCGGATTCGCCGCCATCGCCCGGGACCTCACCCCACGCAACCGCGAGCTGCTTGCTCGCCGCGATGAACTGCAGATG
CTTATCGACGACTACCACCGCAACAACTCCGGCACCATCGACCAAGAGGCGTACGAGGATTTCCTCAAAGAAATCGGATA
CTTGGTTGAGGAGCCAGAAGCTGCAGAAATCCGTACCCAAAACGTCGATACGGAAATCTCCAGCACCGCAGGACCTCAGC
TGGTTGTTCCAATTCTGAACGCACGCTTCGCGCTGAACGCTGCCAATGCTCGCTGGGGTTCCCTCTACGATGCGTTGTAC
GGCACCAACGCCATCCCAGAAACTGATGGCGCTGAAAAGGGCAAGGAGTACAACCCGGTCCGCGGCCAGAAGGTCATCGA
GTGGGGTCGTGAATTCCTCGACAGCGTTGTCCCACTGGACGGTGCTTCGCATGCCGATGTTGAGAAGTACAACATCACCG
ATGGAAAGCTTGCAGCCCACATTGGAGATAGCGTCTACCGACTGAAAAACCGTGAATCCTACCGTGGCTTCACCGGCAAC
TTCCTTGATCCAGAAGCAATCCTGCTGGAAACCAACGGCCTGCACATCGAGCTGCAGATCGATCCTGTCCACCCAATCGG
CAAGGCAGACAAGACTGGTCTCAAAGACATCGTTTTGGAATCTGCGATCACCACGATCATGGACTTCGAAGACTCCGTTG
CAGCTGTTGATGCTGAAGACAAGACCTTAGGTTACTCTAACTGGTTCGGACTCAACACCGGCGAACTGAAAGAAGAGATG
TCCAAGAACGGACGCATCTTCACCCGTGAGCTCAACAAGGACCGCGTCTACATTGGCCGCAATGGTACCGAGCTGGTTCT
GCACGGTCGTTCCCTGCTGTTCGTCCGCAACGTTGGTCACCTCATGCAAAACCCATCCATCTTGATTGATGGCGAGGAGA
TCTTCGAAGGCATCATGGATGCTGTCTTGACCACTGTTTGTGCCATCCCAGGAATTGCTCCGCAGAACAAGATGCGCAAT
TCCCGCAAGGGCTCCATCTACATCGTGAAGCCTAAGCAGCACGGCCCTGAAGAAGTCGCGTTCACCAACGAGCTCTTCGG
CCGCGTTGAGGATCTGCTTGATCTGCCACGCCACACCTTGAAGGTTGGTGTTATGGATGAGGAGCGTCGCACGTCCGTGA
ACCTGGATGCCAGCATCATGGAAGTTGCTGACCGCTTGGCATTCATCAACACTGGCTTCCTGGACCGCACCGGCGATGAA
ATCCACACCTCCATGGAAGCAGGCGCCATGGTGCGCAAGGCTGATATGCAGACCGCACCGTGGAAGCAGGCCTACGAGAA
CAACAACGTTGATGCAGGTATTCAGCGTGGTCTTCCTGGCAAGGCTCAGATCGGTAAGGGCATGTGGGCGATGACTGAAC
TCATGGCAGAAATGCTGGAGAAGAAGATCGGCCAGCCACGCGAAGGCGCCAACACTGCATGGGTTCCTTCACCAACTGGT
GCGACGCTGCACGCAACGCACTACCACTTGGTTGATGTGTTCAAGGTTCAAGACGAACTGCGTGCTGCCGGCCGCCGCGA
CAGCCTGCGCAACATTCTCACCATTCCAACCGCACCAAACACCAATTGGTCTGAGGAAGAGAAGAAGGAAGAGATGGACA
ACAACTGCCAGTCCATCCTCGGATACGTTGTGCGCTGGGTTGAGCACGGTGTTGGTTGCTCCAAGGTTCCAGACATCCAT
GACATCGACCTCATGGAAGACCGCGCAACGCTGCGTATTTCCTCGCAGATGCTGGCCAACTGGATCCGCCATGATGTTGT
CTCGAAGGAGCAGGTCTTGGAGTCACTGGAACGAATGGCAGTGGTCGTCGACAAGCAAAATGCGGGCGACGAGGCCTACC
GCGATATGGCGCCGAACTACGACGCCTCCCTCGCCTTCCAGGCGGCTAAGGACTTGATTTTCGAAGGCACCAAGTCCCCA
TCGGGCTACACCGAGCCCATCTTGCACGCACGCCGCCGCGAGTTCAAAGCAAAAAACTAA

Upstream 100 bases:

>100_bases
TTTTCACAACCGTTAACGGCGTAGCCAAAACAAGAAGGATTCGCATTCTTCTGGTTTAGGCACAGGTCATCTAAAACCCA
TGCTTTAAAAGGAGCCTTCA

Downstream 100 bases:

>100_bases
GCACGCTTTTCGACGCTTACCTGCATCCCAACGGTGACTGACTGCCCCGGAGCCACCCTCACTCCTTTTTGGTCAGCACC
CAAAAGCGCCGGTTCAACAC

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MTEQELLSAQTADNAGTDSTERVDAGGMQVAKVLYDFVTEAVLPRVGVDAEKFWSGFAAIARDLTPRNRELLARRDELQM
LIDDYHRNNSGTIDQEAYEDFLKEIGYLVEEPEAAEIRTQNVDTEISSTAGPQLVVPILNARFALNAANARWGSLYDALY
GTNAIPETDGAEKGKEYNPVRGQKVIEWGREFLDSVVPLDGASHADVEKYNITDGKLAAHIGDSVYRLKNRESYRGFTGN
FLDPEAILLETNGLHIELQIDPVHPIGKADKTGLKDIVLESAITTIMDFEDSVAAVDAEDKTLGYSNWFGLNTGELKEEM
SKNGRIFTRELNKDRVYIGRNGTELVLHGRSLLFVRNVGHLMQNPSILIDGEEIFEGIMDAVLTTVCAIPGIAPQNKMRN
SRKGSIYIVKPKQHGPEEVAFTNELFGRVEDLLDLPRHTLKVGVMDEERRTSVNLDASIMEVADRLAFINTGFLDRTGDE
IHTSMEAGAMVRKADMQTAPWKQAYENNNVDAGIQRGLPGKAQIGKGMWAMTELMAEMLEKKIGQPREGANTAWVPSPTG
ATLHATHYHLVDVFKVQDELRAAGRRDSLRNILTIPTAPNTNWSEEEKKEEMDNNCQSILGYVVRWVEHGVGCSKVPDIH
DIDLMEDRATLRISSQMLANWIRHDVVSKEQVLESLERMAVVVDKQNAGDEAYRDMAPNYDASLAFQAAKDLIFEGTKSP
SGYTEPILHARRREFKAKN

Sequences:

>Translated_739_residues
MTEQELLSAQTADNAGTDSTERVDAGGMQVAKVLYDFVTEAVLPRVGVDAEKFWSGFAAIARDLTPRNRELLARRDELQM
LIDDYHRNNSGTIDQEAYEDFLKEIGYLVEEPEAAEIRTQNVDTEISSTAGPQLVVPILNARFALNAANARWGSLYDALY
GTNAIPETDGAEKGKEYNPVRGQKVIEWGREFLDSVVPLDGASHADVEKYNITDGKLAAHIGDSVYRLKNRESYRGFTGN
FLDPEAILLETNGLHIELQIDPVHPIGKADKTGLKDIVLESAITTIMDFEDSVAAVDAEDKTLGYSNWFGLNTGELKEEM
SKNGRIFTRELNKDRVYIGRNGTELVLHGRSLLFVRNVGHLMQNPSILIDGEEIFEGIMDAVLTTVCAIPGIAPQNKMRN
SRKGSIYIVKPKQHGPEEVAFTNELFGRVEDLLDLPRHTLKVGVMDEERRTSVNLDASIMEVADRLAFINTGFLDRTGDE
IHTSMEAGAMVRKADMQTAPWKQAYENNNVDAGIQRGLPGKAQIGKGMWAMTELMAEMLEKKIGQPREGANTAWVPSPTG
ATLHATHYHLVDVFKVQDELRAAGRRDSLRNILTIPTAPNTNWSEEEKKEEMDNNCQSILGYVVRWVEHGVGCSKVPDIH
DIDLMEDRATLRISSQMLANWIRHDVVSKEQVLESLERMAVVVDKQNAGDEAYRDMAPNYDASLAFQAAKDLIFEGTKSP
SGYTEPILHARRREFKAKN
>Mature_738_residues
TEQELLSAQTADNAGTDSTERVDAGGMQVAKVLYDFVTEAVLPRVGVDAEKFWSGFAAIARDLTPRNRELLARRDELQML
IDDYHRNNSGTIDQEAYEDFLKEIGYLVEEPEAAEIRTQNVDTEISSTAGPQLVVPILNARFALNAANARWGSLYDALYG
TNAIPETDGAEKGKEYNPVRGQKVIEWGREFLDSVVPLDGASHADVEKYNITDGKLAAHIGDSVYRLKNRESYRGFTGNF
LDPEAILLETNGLHIELQIDPVHPIGKADKTGLKDIVLESAITTIMDFEDSVAAVDAEDKTLGYSNWFGLNTGELKEEMS
KNGRIFTRELNKDRVYIGRNGTELVLHGRSLLFVRNVGHLMQNPSILIDGEEIFEGIMDAVLTTVCAIPGIAPQNKMRNS
RKGSIYIVKPKQHGPEEVAFTNELFGRVEDLLDLPRHTLKVGVMDEERRTSVNLDASIMEVADRLAFINTGFLDRTGDEI
HTSMEAGAMVRKADMQTAPWKQAYENNNVDAGIQRGLPGKAQIGKGMWAMTELMAEMLEKKIGQPREGANTAWVPSPTGA
TLHATHYHLVDVFKVQDELRAAGRRDSLRNILTIPTAPNTNWSEEEKKEEMDNNCQSILGYVVRWVEHGVGCSKVPDIHD
IDLMEDRATLRISSQMLANWIRHDVVSKEQVLESLERMAVVVDKQNAGDEAYRDMAPNYDASLAFQAAKDLIFEGTKSPS
GYTEPILHARRREFKAKN

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily

Homologues:

Organism=Escherichia coli, GI1789348, Length=723, Percent_Identity=55.8782849239281, Blast_Score=801, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MASZ_CORGL (P42450)

Other databases:

- EMBL:   X78491
- EMBL:   L27123
- EMBL:   BA000036
- EMBL:   BX927154
- PIR:   I40715
- RefSeq:   NP_601530.1
- RefSeq:   YP_226574.1
- ProteinModelPortal:   P42450
- SMR:   P42450
- GeneID:   1020280
- GeneID:   3345106
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2559
- KEGG:   cgl:NCgl2247
- HOGENOM:   HBG350005
- OMA:   PKMHGPD
- PhylomeDB:   P42450
- ProtClustDB:   PRK02999
- BioCyc:   CGLU196627:CG2559-MONOMER
- BRENDA:   2.3.3.9
- GO:   GO:0005737
- HAMAP:   MF_00641
- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253
- PANTHER:   PTHR21631:SF1
- TIGRFAMs:   TIGR01345

Pfam domain/function: PF01274 Malate_synthase; SSF51645 Malat_synth_like

EC number: =2.3.3.9

Molecular weight: Translated: 82364; Mature: 82233

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: ACT_SITE 356-356 ACT_SITE 647-647

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQELLSAQTADNAGTDSTERVDAGGMQVAKVLYDFVTEAVLPRVGVDAEKFWSGFAAI
CCHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ARDLTPRNRELLARRDELQMLIDDYHRNNSGTIDQEAYEDFLKEIGYLVEEPEAAEIRTQ
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHC
NVDTEISSTAGPQLVVPILNARFALNAANARWGSLYDALYGTNAIPETDGAEKGKEYNPV
CCCCHHHCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RGQKVIEWGREFLDSVVPLDGASHADVEKYNITDGKLAAHIGDSVYRLKNRESYRGFTGN
CHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHCHHHHHHCCCCCCCCCCCC
FLDPEAILLETNGLHIELQIDPVHPIGKADKTGLKDIVLESAITTIMDFEDSVAAVDAED
CCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCC
KTLGYSNWFGLNTGELKEEMSKNGRIFTRELNKDRVYIGRNGTELVLHGRSLLFVRNVGH
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEECCCCCEEEEECCEEEEHHHHHH
LMQNPSILIDGEEIFEGIMDAVLTTVCAIPGIAPQNKMRNSRKGSIYIVKPKQHGPEEVA
HHCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCCCCHHHH
FTNELFGRVEDLLDLPRHTLKVGVMDEERRTSVNLDASIMEVADRLAFINTGFLDRTGDE
HHHHHHHHHHHHHHCCHHHEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHH
IHTSMEAGAMVRKADMQTAPWKQAYENNNVDAGIQRGLPGKAQIGKGMWAMTELMAEMLE
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHCCCCCHHHHCCHHHHHHHHHHHHHH
KKIGQPREGANTAWVPSPTGATLHATHYHLVDVFKVQDELRAAGRRDSLRNILTIPTAPN
HHCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCCC
TNWSEEEKKEEMDNNCQSILGYVVRWVEHGVGCSKVPDIHDIDLMEDRATLRISSQMLAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHH
WIRHDVVSKEQVLESLERMAVVVDKQNAGDEAYRDMAPNYDASLAFQAAKDLIFEGTKSP
HHHHHHCCHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
SGYTEPILHARRREFKAKN
CCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEQELLSAQTADNAGTDSTERVDAGGMQVAKVLYDFVTEAVLPRVGVDAEKFWSGFAAI
CHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ARDLTPRNRELLARRDELQMLIDDYHRNNSGTIDQEAYEDFLKEIGYLVEEPEAAEIRTQ
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHC
NVDTEISSTAGPQLVVPILNARFALNAANARWGSLYDALYGTNAIPETDGAEKGKEYNPV
CCCCHHHCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
RGQKVIEWGREFLDSVVPLDGASHADVEKYNITDGKLAAHIGDSVYRLKNRESYRGFTGN
CHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHCHHHHHHCCCCCCCCCCCC
FLDPEAILLETNGLHIELQIDPVHPIGKADKTGLKDIVLESAITTIMDFEDSVAAVDAED
CCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCC
KTLGYSNWFGLNTGELKEEMSKNGRIFTRELNKDRVYIGRNGTELVLHGRSLLFVRNVGH
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCEEEECCCCCEEEEECCEEEEHHHHHH
LMQNPSILIDGEEIFEGIMDAVLTTVCAIPGIAPQNKMRNSRKGSIYIVKPKQHGPEEVA
HHCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCCCCHHHH
FTNELFGRVEDLLDLPRHTLKVGVMDEERRTSVNLDASIMEVADRLAFINTGFLDRTGDE
HHHHHHHHHHHHHHCCHHHEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHH
IHTSMEAGAMVRKADMQTAPWKQAYENNNVDAGIQRGLPGKAQIGKGMWAMTELMAEMLE
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHCCCCCHHHHCCHHHHHHHHHHHHHH
KKIGQPREGANTAWVPSPTGATLHATHYHLVDVFKVQDELRAAGRRDSLRNILTIPTAPN
HHCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCCC
TNWSEEEKKEEMDNNCQSILGYVVRWVEHGVGCSKVPDIHDIDLMEDRATLRISSQMLAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHH
WIRHDVVSKEQVLESLERMAVVVDKQNAGDEAYRDMAPNYDASLAFQAAKDLIFEGTKSP
HHHHHHCCHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
SGYTEPILHARRREFKAKN
CCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7812449; 12948626