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The map label for this gene is dcp [H]

Identifier: 62391142

GI number: 62391142

Start: 2406477

End: 2408513

Strand: Reverse

Name: dcp [H]

Synonym: cg2527

Alternate gene names: 62391142

Gene position: 2408513-2406477 (Counterclockwise)

Preceding gene: 62391146

Following gene: 62391141

Centisome position: 73.37

GC content: 59.65

Gene sequence:

>2037_bases
ATGACTGTTGAACACCTGCTCAAGCCCAGCACCTTGCCCTACCAGCTGCCCGATTTCGCAGCGATCAAGGTGGCTGATTT
CCCGCCCGCCTTCGAACTCGCATTAGCTGAACACGATGCTGAAATTACAGCGATCGCTACCAATGAGGACGCTCCTACCT
GGGAGAACACCATTGAGGCCCTGGAACGCGCAGGCCTGTCCCTCAACCGCGTCGCCGCCGTATTCTTCAACTTGCAGGGC
ACCGATTCCTCCCCTGAAATGGATGAAATCGCAGCCACTATCGCGCCGAAACTCTCCGCGCATTCGGATGCGATTTTCCA
CAATGCTGCGCTTTTCGCGCGCATTGAGGCCGTAGAAGCACCGGCCGACGAGGAATCGCAACGCCTGTTGTCCCACACCA
AGCGCGCTTTTCGACGTCGCGGTGCAGCACTCAACGCCGACGGCAAGGCCCGACTGAGCACCATCAACCAGCGCCTATCG
GCACTGTCCGAACAGTTCGGCCGCAACCTGCTTCAGGACACCCGCGATCTGGCGGTCAACTTTGAAGAATCTGAACTTGC
CGGTTTTAGCGAAGCCCGCATATCCGCCGCCGCTGACTACGCAGCAGCAGTTGGCACCGAAGGCTACGTGGTTCCACTGG
AACTGCCCACCGTGCAGTCAGAGCAGGCAGTATTAACCGAATCCGCCTCGCGTGCAAAGCTTTATGAAGCCTCCCAGAAG
CGTGGCGCCAGCCTGAACAAGGACGTGCTGCTCGAAACCGTGCGTCTGCGTGCTGAACGCGCCACACTTTTAGGCTACGA
CACCCACGCCGATTACGTCATCGAAGAAGAAACCGCCGATGACGTCGCAGCCGTGCGCGCCTTGCTTTATGATCTCGCCC
CAGCCGCCTCTGCCAATGCGAAAGCCGAATACAAACTCTCCGCAGAAGAAGCAGAAGAACACGGCCAAAAAGTCGGCGCA
GCTGACTGGAGCTTCTGGGAAGCCAAAGTCCGCGCCCGCGACTACGCCCTGGACGAAACCGAACTGCGCAACTACTTCCC
ATTGAACCAAGTACTCCGTGACGGCGTCTTCTTCGCTGCTAACCGCCTCTACGGAATCACCGTGGAACCACGCCCTGACC
TGCGCGGTTACGCCGAGGGCGTGGACGTCTGGGAAGTCCTCGATTCTGACGGCTCCGGCATCGGCCTGATCCTTACCGAC
TACTACGGCCGACCATCCAAGCGGGGCGGCGCTTGGATGTCCAGCTTTGTCGACCAATCCGAGCTGCTAGGCACCAAGCC
AGTCGTGGTCAACGTTATGGGTATTACCAAACCAACCACCGGCGAAGCACTACTCAGCCTCGATGAAGTAACCACCATCT
TCCACGAATTCGGCCACGGCCTGCACGGCTTGCTGTCCAAGGTGCGCTACCCAAGCTTCTCCGGAACCTCCGTGCCCCGC
GACTACGTAGAATTCCCCTCCCAGATCAACGAAAACTGGGCATTCGACCCTGCAGTAGTCCGCAACTACGCCCGCCACGT
GGACACCGGCGACATCATTCCAGACTCCCTGCTTGAGGCAGTGGAAGCATCCCGCCAATTCGGACAAGGTTTTGCCACCT
CCGAATACTTGGCAGCATCGATTATCGACCTGGCCTGGCACTCCCTGTCCACAGCGGAAGCCGCAGCAGTCAATGACATT
GACCAATTCGAAGCCGACGCACTAGCCGCAGCAGGCCTCGACGTGGACAACATTGCACCGCGCTACCGATCCACCTACTT
CAACCACATCTTTGCTGGCGGCTACTCAGCCGGCTACTACTCCTACCTGTGGGCGGAAGCACTCGACGCCGACGGCTTCG
ACTGGTTTCGCGAAGAAGGCGCAGCCGGATCCGTGGCTTCCCTCGACGCAGCCCGCACCGCCGGCCAGAAATTCCGTGAC
CTGGTCTTATCCCGCGGCGCAGCCTCCGACTACAGCAACGCCTTCGAAGAACTCCGTGGCCGTTCCAAAGACCTCGGCCC
ACTTCTGCGCCGCCGAGGTCTGGCTGGGGCAATCTAA

Upstream 100 bases:

>100_bases
AAATAATGGGGCTCGCCGGTGATGGTTCCCGCCGGGCATTCAACGGTGACGGAAGAGGTGGCAGACATGATGAAAACTCT
AGCAACTAGTATCGGTCACT

Downstream 100 bases:

>100_bases
ACAACCCGGTGTAGGCTAATAACCCATGACTGCATTCCTCGACCGGATCTCACAGCTGCTTACAACATCACCGCTGTGGA
TCCAGTCACCGATCGTCATC

Product: peptidyl-dipeptidase A protein

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MTVEHLLKPSTLPYQLPDFAAIKVADFPPAFELALAEHDAEITAIATNEDAPTWENTIEALERAGLSLNRVAAVFFNLQG
TDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEAPADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLS
ALSEQFGRNLLQDTRDLAVNFEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
RGASLNKDVLLETVRLRAERATLLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANAKAEYKLSAEEAEEHGQKVGA
ADWSFWEAKVRARDYALDETELRNYFPLNQVLRDGVFFAANRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTD
YYGRPSKRGGAWMSSFVDQSELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVEASRQFGQGFATSEYLAASIIDLAWHSLSTAEAAAVNDI
DQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYYSYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRD
LVLSRGAASDYSNAFEELRGRSKDLGPLLRRRGLAGAI

Sequences:

>Translated_678_residues
MTVEHLLKPSTLPYQLPDFAAIKVADFPPAFELALAEHDAEITAIATNEDAPTWENTIEALERAGLSLNRVAAVFFNLQG
TDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEAPADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLS
ALSEQFGRNLLQDTRDLAVNFEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
RGASLNKDVLLETVRLRAERATLLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANAKAEYKLSAEEAEEHGQKVGA
ADWSFWEAKVRARDYALDETELRNYFPLNQVLRDGVFFAANRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTD
YYGRPSKRGGAWMSSFVDQSELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVEASRQFGQGFATSEYLAASIIDLAWHSLSTAEAAAVNDI
DQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYYSYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRD
LVLSRGAASDYSNAFEELRGRSKDLGPLLRRRGLAGAI
>Mature_677_residues
TVEHLLKPSTLPYQLPDFAAIKVADFPPAFELALAEHDAEITAIATNEDAPTWENTIEALERAGLSLNRVAAVFFNLQGT
DSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEAPADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLSA
LSEQFGRNLLQDTRDLAVNFEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQKR
GASLNKDVLLETVRLRAERATLLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANAKAEYKLSAEEAEEHGQKVGAA
DWSFWEAKVRARDYALDETELRNYFPLNQVLRDGVFFAANRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTDY
YGRPSKRGGAWMSSFVDQSELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPRD
YVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVEASRQFGQGFATSEYLAASIIDLAWHSLSTAEAAAVNDID
QFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYYSYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRDL
VLSRGAASDYSNAFEELRGRSKDLGPLLRRRGLAGAI

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=566, Percent_Identity=30.2120141342756, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI14149738, Length=644, Percent_Identity=27.3291925465839, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI156105687, Length=633, Percent_Identity=22.5908372827804, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1787819, Length=690, Percent_Identity=39.7101449275362, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1789913, Length=692, Percent_Identity=30.7803468208092, Blast_Score=289, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI32565901, Length=501, Percent_Identity=21.7564870259481, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319793, Length=658, Percent_Identity=24.6200607902736, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322715, Length=579, Percent_Identity=22.9706390328152, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356111, Length=455, Percent_Identity=24.3956043956044, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI20129717, Length=417, Percent_Identity=27.5779376498801, Blast_Score=123, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 73881; Mature: 73749

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEHLLKPSTLPYQLPDFAAIKVADFPPAFELALAEHDAEITAIATNEDAPTWENTIEA
CCHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
LERAGLSLNRVAAVFFNLQGTDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEA
HHHCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
PADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLSALSEQFGRNLLQDTRDLAVN
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
FEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
CCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCHHHHHHHHHHHH
RGASLNKDVLLETVRLRAERATLLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANA
CCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCC
KAEYKLSAEEAEEHGQKVGAADWSFWEAKVRARDYALDETELRNYFPLNQVLRDGVFFAA
CCEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHCCHHEEE
NRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTDYYGRPSKRGGAWMSSFVDQS
CCEEEEEECCCCCCCHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCH
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVEASRQFGQGFATSEYLAAS
HHHHCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
IIDLAWHSLSTAEAAAVNDIDQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCCHHH
SYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRDLVLSRGAASDYSNAFEELRG
HHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RSKDLGPLLRRRGLAGAI
CCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVEHLLKPSTLPYQLPDFAAIKVADFPPAFELALAEHDAEITAIATNEDAPTWENTIEA
CHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
LERAGLSLNRVAAVFFNLQGTDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEA
HHHCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
PADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLSALSEQFGRNLLQDTRDLAVN
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
FEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
CCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCHHHHHHHHHHHH
RGASLNKDVLLETVRLRAERATLLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANA
CCCCCCHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCC
KAEYKLSAEEAEEHGQKVGAADWSFWEAKVRARDYALDETELRNYFPLNQVLRDGVFFAA
CCEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHCCHHEEE
NRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTDYYGRPSKRGGAWMSSFVDQS
CCEEEEEECCCCCCCHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCH
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVEASRQFGQGFATSEYLAAS
HHHHCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
IIDLAWHSLSTAEAAAVNDIDQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCCHHH
SYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRDLVLSRGAASDYSNAFEELRG
HHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RSKDLGPLLRRRGLAGAI
CCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537804; 11677609 [H]