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The map label for this gene is glnD

Identifier: 62390896

GI number: 62390896

Start: 2139713

End: 2141791

Strand: Reverse

Name: glnD

Synonym: cg2258

Alternate gene names: 62390896

Gene position: 2141791-2139713 (Counterclockwise)

Preceding gene: 62390897

Following gene: 62390895

Centisome position: 65.24

GC content: 57.62

Gene sequence:

>2079_bases
ATGAATAATCCAGCCCAGCTGCGCCAAGATACTGAAAAGGAAGTCCTGGCGTTGCTGGGCTCTTTGGTTTTACCCGCCGG
CACCGCGCTTGCCGCCACCGGATCTTTGGCCAGGTCCGAACTCACGCCGTATTCCGATTTGGACCTCATTTTGATCCATC
CACCAGGAGCCACCCCGGATGGCGTGGAGGATTTGTGGTACCCGATTTGGGACGCAAAAAAGCGTCTCGACTACTCCGTG
CGCACCCCAGATGAGTGTGTGGCTATGATTTCTGCGGATTCCACTGCAGCCCTTGCCATGCTTGACCTGCGGTTTGTCGC
TGGCGATGAGGATCTGTGTGCCAAAACGCGCCGGCGCATCGTGGAGAAGTGGCGCCAGGAACTCAACAAAAACTTCGATG
CCGTTGTGGACACCGCGATTGCCCGTTGGCGCCGCTCCGGACCCGTCGTGGCAATGACGCGGCCAGATCTTAAACACGGC
AGGGGAGGGCTGCGCGATTTCGAACTGATCAAGGCCCTCGCGCTCGGCCACCTATGCAACCTTCCACAGCTTGATGCGCA
ACACCAGCTGCTTCTCGACGCCCGCACCTTGCTGCACGTCCACGCGCGACGCTCCCGCGACGTCCTTGACCCCGAATTTG
CGGTGGATGTGGCCATGGATTTGGGCTTTGTTGACCGCTATCACCTGGGCCGGGAGATCGCCGATGCAGCCCGCGCCATT
GATGATGGCCTGACCACCGCGCTGGCCACCGCCCGTGGCATTTTGCCACGTCGCACAGGTTTTGCATTCAGGAATGCTTC
TCGACGCCCACTTGATCTTGATGTCGTCGACGCCAACGGCACCATCGAATTGTCCAAAAAACCAGATCTTAATGATCCCG
CACTTCCACTTCGAGTGGCCGCAGCCGCAGCAACCACCGGACTTCCGGTGGCAGAATCAACCTGGGTTCGACTTAATGAA
TGCCCGCCACTTCCTGAGCCATGGCCTGCCAATGCAGCAGGGGACTTCTTTCGGATTCTCTCCAGTCCGAAAAACTCACG
CCGAGTGGTGAAAAATATGGATCGCCACGGATTGTGGTCGCGTTTTGTTCCAGAATGGGACCGCATCAAAGGGCTTATGC
CCCGTGAACCCAGCCATATTTCCACCATCGATGAACATAGTCTGAACACTGTTGCAGGATGTGCGCTAGAAACTGTGACC
GTCGCGCGCCCCGATCTTTTAGTTTTGGGAGCCTTGTACCACGACATTGGCAAGGGCTTCCCGCGTCCACACGAACAAGT
AGGTGCAGAGATGGTGGCGAGGGCTGCAAGCCGCATGGGATTGAACCTTCGCGATCGTGCCAGCGTGCAAACGCTGGTCG
CCGAGCACACCGCGGTGGCCAAAATCGCCGCGCGCCTTGATCCCTCCTCGGAGGGCGCCGTCGATAAGCTGCTTGATGCT
GTTAGGTATGACCTGGTGACATTGAATCTGCTTGAGGTGCTAACAGAAGCTGATGCGAAAGCCACGGGGCCTGGCGTGTG
GACGGCGCGTTTGGAGCATGCGCTGCGGATTGTGTGCAAGCGTGCGCGTGATCGCCTCACCGATATTCGCCCGGTTGCGC
CGATGATTGCGCCACGTAGTGAAATTGGTTTGGTGGAACGCGATGGCGTGTTCACAGTGCAATGGCACGGCGAAGACTTA
CATCGGATTCTTGGCGTAATTTATGCCAAAGGATGGACAATCACCGCGGCGCGCATGCTGGCCAATGGTCAATGGAGTGC
GGAATTTGATGTCCGCGCAAACGGCCCCCAAGATTTTGATCCGCAGCATTTCCTGCAGGCATATCAATCCGGTGTGTTTT
CCGAGGTTCCCATTCCAGCACTTGGGATAACAGCCACATTTTGGCACGGGAACACTTTAGAAGTGCGCACTGAGCTTCGC
ACAGGAGCTATTTTTGCCCTGCTCAGAACATTGCCCGATGCCCTCTGGATCAACGCTGTGACCCGCGGTGCGACCCTGAT
TATCCAGGCAGCACTGAAGCCCGGCTTCGATCGAGCAACGGTGGAACGCTCCGTAGTCAGGTCGTTGGCAGGTAGCTGA

Upstream 100 bases:

>100_bases
CACCGGCAAAGTCGGCGACGGCAAAGTGTGGATGACTAACATCGAAGAGCTGGTTCGTGTTCGTACCGGTGAGCGCGGCG
AAGCAGCCCTTTAAAAACTT

Downstream 100 bases:

>100_bases
CGTGACCTGAGCGGGGGCAACCGGCTAACATGTAGGGATTAGCAACCCCGCACTCTAGAACCTACTGGGAGTTCATTCGT
GTTTGAGTCACTGTCCGATC

Product: PII uridylyl-transferase

Products: NA

Alternate protein names: PII uridylyl-transferase; UTase; Uridylyl-removing enzyme

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MNNPAQLRQDTEKEVLALLGSLVLPAGTALAATGSLARSELTPYSDLDLILIHPPGATPDGVEDLWYPIWDAKKRLDYSV
RTPDECVAMISADSTAALAMLDLRFVAGDEDLCAKTRRRIVEKWRQELNKNFDAVVDTAIARWRRSGPVVAMTRPDLKHG
RGGLRDFELIKALALGHLCNLPQLDAQHQLLLDARTLLHVHARRSRDVLDPEFAVDVAMDLGFVDRYHLGREIADAARAI
DDGLTTALATARGILPRRTGFAFRNASRRPLDLDVVDANGTIELSKKPDLNDPALPLRVAAAAATTGLPVAESTWVRLNE
CPPLPEPWPANAAGDFFRILSSPKNSRRVVKNMDRHGLWSRFVPEWDRIKGLMPREPSHISTIDEHSLNTVAGCALETVT
VARPDLLVLGALYHDIGKGFPRPHEQVGAEMVARAASRMGLNLRDRASVQTLVAEHTAVAKIAARLDPSSEGAVDKLLDA
VRYDLVTLNLLEVLTEADAKATGPGVWTARLEHALRIVCKRARDRLTDIRPVAPMIAPRSEIGLVERDGVFTVQWHGEDL
HRILGVIYAKGWTITAARMLANGQWSAEFDVRANGPQDFDPQHFLQAYQSGVFSEVPIPALGITATFWHGNTLEVRTELR
TGAIFALLRTLPDALWINAVTRGATLIIQAALKPGFDRATVERSVVRSLAGS

Sequences:

>Translated_692_residues
MNNPAQLRQDTEKEVLALLGSLVLPAGTALAATGSLARSELTPYSDLDLILIHPPGATPDGVEDLWYPIWDAKKRLDYSV
RTPDECVAMISADSTAALAMLDLRFVAGDEDLCAKTRRRIVEKWRQELNKNFDAVVDTAIARWRRSGPVVAMTRPDLKHG
RGGLRDFELIKALALGHLCNLPQLDAQHQLLLDARTLLHVHARRSRDVLDPEFAVDVAMDLGFVDRYHLGREIADAARAI
DDGLTTALATARGILPRRTGFAFRNASRRPLDLDVVDANGTIELSKKPDLNDPALPLRVAAAAATTGLPVAESTWVRLNE
CPPLPEPWPANAAGDFFRILSSPKNSRRVVKNMDRHGLWSRFVPEWDRIKGLMPREPSHISTIDEHSLNTVAGCALETVT
VARPDLLVLGALYHDIGKGFPRPHEQVGAEMVARAASRMGLNLRDRASVQTLVAEHTAVAKIAARLDPSSEGAVDKLLDA
VRYDLVTLNLLEVLTEADAKATGPGVWTARLEHALRIVCKRARDRLTDIRPVAPMIAPRSEIGLVERDGVFTVQWHGEDL
HRILGVIYAKGWTITAARMLANGQWSAEFDVRANGPQDFDPQHFLQAYQSGVFSEVPIPALGITATFWHGNTLEVRTELR
TGAIFALLRTLPDALWINAVTRGATLIIQAALKPGFDRATVERSVVRSLAGS
>Mature_692_residues
MNNPAQLRQDTEKEVLALLGSLVLPAGTALAATGSLARSELTPYSDLDLILIHPPGATPDGVEDLWYPIWDAKKRLDYSV
RTPDECVAMISADSTAALAMLDLRFVAGDEDLCAKTRRRIVEKWRQELNKNFDAVVDTAIARWRRSGPVVAMTRPDLKHG
RGGLRDFELIKALALGHLCNLPQLDAQHQLLLDARTLLHVHARRSRDVLDPEFAVDVAMDLGFVDRYHLGREIADAARAI
DDGLTTALATARGILPRRTGFAFRNASRRPLDLDVVDANGTIELSKKPDLNDPALPLRVAAAAATTGLPVAESTWVRLNE
CPPLPEPWPANAAGDFFRILSSPKNSRRVVKNMDRHGLWSRFVPEWDRIKGLMPREPSHISTIDEHSLNTVAGCALETVT
VARPDLLVLGALYHDIGKGFPRPHEQVGAEMVARAASRMGLNLRDRASVQTLVAEHTAVAKIAARLDPSSEGAVDKLLDA
VRYDLVTLNLLEVLTEADAKATGPGVWTARLEHALRIVCKRARDRLTDIRPVAPMIAPRSEIGLVERDGVFTVQWHGEDL
HRILGVIYAKGWTITAARMLANGQWSAEFDVRANGPQDFDPQHFLQAYQSGVFSEVPIPALGITATFWHGNTLEVRTELR
TGAIFALLRTLPDALWINAVTRGATLIIQAALKPGFDRATVERSVVRSLAGS

Specific function: Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein

COG id: COG2844

COG function: function code O; UTP:GlnB (protein PII) uridylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glnD family

Homologues:

Organism=Escherichia coli, GI1786363, Length=551, Percent_Identity=25.7713248638838, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLND_CORGL (Q9X706)

Other databases:

- EMBL:   AJ010319
- EMBL:   BA000036
- EMBL:   BX927154
- RefSeq:   NP_601262.1
- RefSeq:   YP_226298.1
- ProteinModelPortal:   Q9X706
- GeneID:   1020013
- GeneID:   3343788
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2258
- KEGG:   cgl:NCgl1981
- HOGENOM:   HBG428777
- OMA:   DTAIARW
- PhylomeDB:   Q9X706
- ProtClustDB:   PRK00227
- BioCyc:   CGLU196627:CG2258-MONOMER
- BRENDA:   2.7.7.59
- HAMAP:   MF_00277
- InterPro:   IPR010043
- InterPro:   IPR003607
- InterPro:   IPR002934
- InterPro:   IPR013546
- PANTHER:   PTHR13734:SF1
- SMART:   SM00471

Pfam domain/function: PF08335 GlnD_UR_UTase; PF01909 NTP_transf_2

EC number: =2.7.7.59

Molecular weight: Translated: 75971; Mature: 75971

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPAQLRQDTEKEVLALLGSLVLPAGTALAATGSLARSELTPYSDLDLILIHPPGATPD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
GVEDLWYPIWDAKKRLDYSVRTPDECVAMISADSTAALAMLDLRFVAGDEDLCAKTRRRI
CHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCHHHHHHHHHHEECCCHHHHHHHHHHH
VEKWRQELNKNFDAVVDTAIARWRRSGPVVAMTRPDLKHGRGGLRDFELIKALALGHLCN
HHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHHHHCC
LPQLDAQHQLLLDARTLLHVHARRSRDVLDPEFAVDVAMDLGFVDRYHLGREIADAARAI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DDGLTTALATARGILPRRTGFAFRNASRRPLDLDVVDANGTIELSKKPDLNDPALPLRVA
HHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHH
AAAATTGLPVAESTWVRLNECPPLPEPWPANAAGDFFRILSSPKNSRRVVKNMDRHGLWS
HHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHH
RFVPEWDRIKGLMPREPSHISTIDEHSLNTVAGCALETVTVARPDLLVLGALYHDIGKGF
HHCCCHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCC
PRPHEQVGAEMVARAASRMGLNLRDRASVQTLVAEHTAVAKIAARLDPSSEGAVDKLLDA
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VRYDLVTLNLLEVLTEADAKATGPGVWTARLEHALRIVCKRARDRLTDIRPVAPMIAPRS
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHH
EIGLVERDGVFTVQWHGEDLHRILGVIYAKGWTITAARMLANGQWSAEFDVRANGPQDFD
HCCEEECCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
PQHFLQAYQSGVFSEVPIPALGITATFWHGNTLEVRTELRTGAIFALLRTLPDALWINAV
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHH
TRGATLIIQAALKPGFDRATVERSVVRSLAGS
HCCHHEEEEEHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNPAQLRQDTEKEVLALLGSLVLPAGTALAATGSLARSELTPYSDLDLILIHPPGATPD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
GVEDLWYPIWDAKKRLDYSVRTPDECVAMISADSTAALAMLDLRFVAGDEDLCAKTRRRI
CHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCHHHHHHHHHHEECCCHHHHHHHHHHH
VEKWRQELNKNFDAVVDTAIARWRRSGPVVAMTRPDLKHGRGGLRDFELIKALALGHLCN
HHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHHHHCC
LPQLDAQHQLLLDARTLLHVHARRSRDVLDPEFAVDVAMDLGFVDRYHLGREIADAARAI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DDGLTTALATARGILPRRTGFAFRNASRRPLDLDVVDANGTIELSKKPDLNDPALPLRVA
HHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHH
AAAATTGLPVAESTWVRLNECPPLPEPWPANAAGDFFRILSSPKNSRRVVKNMDRHGLWS
HHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHH
RFVPEWDRIKGLMPREPSHISTIDEHSLNTVAGCALETVTVARPDLLVLGALYHDIGKGF
HHCCCHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCC
PRPHEQVGAEMVARAASRMGLNLRDRASVQTLVAEHTAVAKIAARLDPSSEGAVDKLLDA
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VRYDLVTLNLLEVLTEADAKATGPGVWTARLEHALRIVCKRARDRLTDIRPVAPMIAPRS
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHH
EIGLVERDGVFTVQWHGEDLHRILGVIYAKGWTITAARMLANGQWSAEFDVRANGPQDFD
HCCEEECCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
PQHFLQAYQSGVFSEVPIPALGITATFWHGNTLEVRTELRTGAIFALLRTLPDALWINAV
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHH
TRGATLIIQAALKPGFDRATVERSVVRSLAGS
HCCHHEEEEEHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10227160; 12948626