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The map label for this gene is lepB [H]

Identifier: 62390873

GI number: 62390873

Start: 2117308

End: 2118096

Strand: Reverse

Name: lepB [H]

Synonym: cg2232

Alternate gene names: 62390873

Gene position: 2118096-2117308 (Counterclockwise)

Preceding gene: 62390875

Following gene: 62390872

Centisome position: 64.52

GC content: 54.12

Gene sequence:

>789_bases
GTGACTGATTTTTCTAGTGCTTCAAATGCTGACGATTCCACGCAGGACGGTCGTCCTGGTCGACGTGCTGGAAAGTCTAA
GAAGGAATCGAAGCCAACTCCGTGGTACATCGAAATTCCAGTGGTTGTGGTTTTGACCCTCGCGCTGATTTTCGTGCTCC
AGACGTTTGTCGGACGCATGTACATGATTCCGAGTGGTTCGATGGAACCTACTTTGCACGGATGTGAGGGCTGCACGGGT
GACCGCATCCTGGTGGAGAAGGTTTCTTACTACTTCACGGATCCAGAGCCGGGCGATGTTGTGGTGTTCAAGGGTACTGA
TTCCTGGAACGTTGGATTCACTACGCAGCGTTCCGATAATTCGGTGATCCGCGGCCTGCAGAACCTGGGTTCTTACGTGG
GTCTTGTCGCACCTGATGAAAATGACCTGGTCAAGCGCATTATCGCCACCGGCGGTCAGACTGTTTCGTGCCAAGCCGGT
GATCCTGGAATCATGGTTGACGGCAAGGAAGTCGATGACAGCTACACGCTGCAACCTGCGCAATTCCCCATCGATGAGAC
CTCCGGTTCCACCGAATGCGGCGGCAACTATTTCGGCCCCATCACCGTGCCTGGCGGCAACTACTTCATGATGGGTGACA
ACCGCACCAACTCCATGGATTCCCGCTACCACCTGGGCGATCAGTACCAAGGAACCATCCCTGAGGAAAACATCAAGGGC
AAAGTTCAAGCAATTATCCTGCCATTTAGCCGAATCGGTGGCGTCGACGACCCTGCCATCAAAGGCTAG

Upstream 100 bases:

>100_bases
AGGCGCATGGCGCCGAGGTGCAGCTTTGGGCGAAGAAGTATTTTTCGGCACACGTGTGATTCAGGTCAGCCTTAATGTAA
TGCTGCTAGAGTGAACTCCC

Downstream 100 bases:

>100_bases
TAATTCGCTTTTCGACGCCCCCCTCAATGCGACGCTTAAAGCATCTACGGACCTTTGAGGTCACCTTGTCACGCAACGGG
CTAGGGCCCGTTGCAGGAGT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTDFSSASNADDSTQDGRPGRRAGKSKKESKPTPWYIEIPVVVVLTLALIFVLQTFVGRMYMIPSGSMEPTLHGCEGCTG
DRILVEKVSYYFTDPEPGDVVVFKGTDSWNVGFTTQRSDNSVIRGLQNLGSYVGLVAPDENDLVKRIIATGGQTVSCQAG
DPGIMVDGKEVDDSYTLQPAQFPIDETSGSTECGGNYFGPITVPGGNYFMMGDNRTNSMDSRYHLGDQYQGTIPEENIKG
KVQAIILPFSRIGGVDDPAIKG

Sequences:

>Translated_262_residues
MTDFSSASNADDSTQDGRPGRRAGKSKKESKPTPWYIEIPVVVVLTLALIFVLQTFVGRMYMIPSGSMEPTLHGCEGCTG
DRILVEKVSYYFTDPEPGDVVVFKGTDSWNVGFTTQRSDNSVIRGLQNLGSYVGLVAPDENDLVKRIIATGGQTVSCQAG
DPGIMVDGKEVDDSYTLQPAQFPIDETSGSTECGGNYFGPITVPGGNYFMMGDNRTNSMDSRYHLGDQYQGTIPEENIKG
KVQAIILPFSRIGGVDDPAIKG
>Mature_261_residues
TDFSSASNADDSTQDGRPGRRAGKSKKESKPTPWYIEIPVVVVLTLALIFVLQTFVGRMYMIPSGSMEPTLHGCEGCTGD
RILVEKVSYYFTDPEPGDVVVFKGTDSWNVGFTTQRSDNSVIRGLQNLGSYVGLVAPDENDLVKRIIATGGQTVSCQAGD
PGIMVDGKEVDDSYTLQPAQFPIDETSGSTECGGNYFGPITVPGGNYFMMGDNRTNSMDSRYHLGDQYQGTIPEENIKGK
VQAIILPFSRIGGVDDPAIKG

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28301; Mature: 28170

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00501 SPASE_I_1 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFSSASNADDSTQDGRPGRRAGKSKKESKPTPWYIEIPVVVVLTLALIFVLQTFVGRM
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCEE
YMIPSGSMEPTLHGCEGCTGDRILVEKVSYYFTDPEPGDVVVFKGTDSWNVGFTTQRSDN
EECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCEEECCCCH
SVIRGLQNLGSYVGLVAPDENDLVKRIIATGGQTVSCQAGDPGIMVDGKEVDDSYTLQPA
HHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCEEECCC
QFPIDETSGSTECGGNYFGPITVPGGNYFMMGDNRTNSMDSRYHLGDQYQGTIPEENIKG
CCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCC
KVQAIILPFSRIGGVDDPAIKG
EEEEEEEEHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDFSSASNADDSTQDGRPGRRAGKSKKESKPTPWYIEIPVVVVLTLALIFVLQTFVGRM
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCEE
YMIPSGSMEPTLHGCEGCTGDRILVEKVSYYFTDPEPGDVVVFKGTDSWNVGFTTQRSDN
EECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCEEECCCCH
SVIRGLQNLGSYVGLVAPDENDLVKRIIATGGQTVSCQAGDPGIMVDGKEVDDSYTLQPA
HHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCEEECCCCCCCCEEECCC
QFPIDETSGSTECGGNYFGPITVPGGNYFMMGDNRTNSMDSRYHLGDQYQGTIPEENIKG
CCCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCC
KVQAIILPFSRIGGVDDPAIKG
EEEEEEEEHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]