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The map label for this gene is rnhB [H]

Identifier: 62390872

GI number: 62390872

Start: 2116613

End: 2117281

Strand: Reverse

Name: rnhB [H]

Synonym: cg2230

Alternate gene names: 62390872

Gene position: 2117281-2116613 (Counterclockwise)

Preceding gene: 62390873

Following gene: 62390871

Centisome position: 64.5

GC content: 56.65

Gene sequence:

>669_bases
ATGCGACGCTTAAAGCATCTACGGACCTTTGAGGTCACCTTGTCACGCAACGGGCTAGGGCCCGTTGCAGGAGTAGACGA
AGCTGGACGCGGTGCCTGCTGCGGACCCATTTCAATTGCCGCATGCATACTCCCGGACAAACCCATCCAGGAGCTAGCCG
CACTGACAGACTCCAAAAAGCTCAGTGCCAGCACCCGCGAAAAACTCATGCCACTGATCAAAAAACACGCACTCGCTTGG
TCAGTCATCGTGATCTCCGCCCAAGACATCGACCGATTTGGCATCCAACACGCAAACATCTCCGGCATGCGACGAGCCGT
AGCCGCCCTAGGCACCCAACCCGGCTACGTACTTACCGACGCCATGAAAGTCCCCGGCTTCACAGTCCCATACCTACCCA
TCATCGGCGGAGACGCCTCCGCCCGATGCATCGCCGCCGCAAGTGTATTAGCCAAACAAACCCGCGACGACATCATGACC
GACATGGCCAACGACTACCCGCACTACGGTCTCGAAATTCACAAAGGCTACAGTACGAAGATCCACATGGATGCGGTGCG
CCACCACGGCGCAAGTCCCGAGCACAGATATAGTTATGCAAATGTGGCCAAGGCACACCAAGAATGGCTACACGCTGCAG
ATAATGACACGACGGAAGGTGGAGCATGA

Upstream 100 bases:

>100_bases
AGGGCAAAGTTCAAGCAATTATCCTGCCATTTAGCCGAATCGGTGGCGTCGACGACCCTGCCATCAAAGGCTAGTAATTC
GCTTTTCGACGCCCCCCTCA

Downstream 100 bases:

>100_bases
GCGCTGAAGAACTCGACAACTACGAAGCAGAGGTTGAACTCTCTCTTTACCGCGAATACCGCGACGTAGTCAGCCAGTTT
TCCTATGTTGTAGAAACTGA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRRLKHLRTFEVTLSRNGLGPVAGVDEAGRGACCGPISIAACILPDKPIQELAALTDSKKLSASTREKLMPLIKKHALAW
SVIVISAQDIDRFGIQHANISGMRRAVAALGTQPGYVLTDAMKVPGFTVPYLPIIGGDASARCIAAASVLAKQTRDDIMT
DMANDYPHYGLEIHKGYSTKIHMDAVRHHGASPEHRYSYANVAKAHQEWLHAADNDTTEGGA

Sequences:

>Translated_222_residues
MRRLKHLRTFEVTLSRNGLGPVAGVDEAGRGACCGPISIAACILPDKPIQELAALTDSKKLSASTREKLMPLIKKHALAW
SVIVISAQDIDRFGIQHANISGMRRAVAALGTQPGYVLTDAMKVPGFTVPYLPIIGGDASARCIAAASVLAKQTRDDIMT
DMANDYPHYGLEIHKGYSTKIHMDAVRHHGASPEHRYSYANVAKAHQEWLHAADNDTTEGGA
>Mature_222_residues
MRRLKHLRTFEVTLSRNGLGPVAGVDEAGRGACCGPISIAACILPDKPIQELAALTDSKKLSASTREKLMPLIKKHALAW
SVIVISAQDIDRFGIQHANISGMRRAVAALGTQPGYVLTDAMKVPGFTVPYLPIIGGDASARCIAAASVLAKQTRDDIMT
DMANDYPHYGLEIHKGYSTKIHMDAVRHHGASPEHRYSYANVAKAHQEWLHAADNDTTEGGA

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=185, Percent_Identity=43.7837837837838, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 23934; Mature: 23934

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLKHLRTFEVTLSRNGLGPVAGVDEAGRGACCGPISIAACILPDKPIQELAALTDSKK
CCHHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHHHHCCHH
LSASTREKLMPLIKKHALAWSVIVISAQDIDRFGIQHANISGMRRAVAALGTQPGYVLTD
HHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEC
AMKVPGFTVPYLPIIGGDASARCIAAASVLAKQTRDDIMTDMANDYPHYGLEIHKGYSTK
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCE
IHMDAVRHHGASPEHRYSYANVAKAHQEWLHAADNDTTEGGA
EEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRRLKHLRTFEVTLSRNGLGPVAGVDEAGRGACCGPISIAACILPDKPIQELAALTDSKK
CCHHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHHHHCCHH
LSASTREKLMPLIKKHALAWSVIVISAQDIDRFGIQHANISGMRRAVAALGTQPGYVLTD
HHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEC
AMKVPGFTVPYLPIIGGDASARCIAAASVLAKQTRDDIMTDMANDYPHYGLEIHKGYSTK
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCE
IHMDAVRHHGASPEHRYSYANVAKAHQEWLHAADNDTTEGGA
EEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA