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The map label for this gene is dinF [H]

Identifier: 62390822

GI number: 62390822

Start: 2060798

End: 2062111

Strand: Reverse

Name: dinF [H]

Synonym: cg2173

Alternate gene names: 62390822

Gene position: 2062111-2060798 (Counterclockwise)

Preceding gene: 62390823

Following gene: 62390821

Centisome position: 62.82

GC content: 52.59

Gene sequence:

>1314_bases
ATGTCGATGTCTAACAACGACTTTGAGCATGAGTCCCATGATGTTTCTGCAAAGCAGATCTTCGGGCTCGCGTTCCCCGC
ACTGGGTGTTCTAGCTGCGATGCCGCTGTATCTCTTGTTGGATACAGCGGTTGTTGGCACTTTGGGTGGCTTCGAATTGG
CTGCGTTGGGCGCAGCAACAACAATTCAAGCTCAAGTGACAACACAGCTGACATTCTTGTCCTATGGAACTACCGCGAGA
TCATCGAGAATTTTCGGAATGGGTGATCGCCGGGGAGCAATTGCCGAAGGTGTGCAAGCAACCTGGGTGGCACTCTTTGT
AGGCTTGGGCATCTTAACGCTGATGCTCATTGGAGCCCCGACTTTCGCGTTGTGGCTCAGTGGTGATGAAGCTCTAGCCC
AAGAAGCAGGGCATTGGCTCCGGGTCGCTGCTTTTGCGGTGCCACTAATTCTCATGATCATGGCTGGCAACGGTTGGTTA
AGAGGTATTCAAAACACCAAGCTGCCACTCTATTTCACCTTGGCGGGAGTCATCCCCGGCGCGATCTTGATTCCGATATT
CGTGGCTAAGTTTGGACTTGTGGGCTCTGCCTGGGCAAACCTCATTGCAGAAGCAATTACTGCTTCGCTGTTTTTGGGTG
CATTGATCAAGCACCACGAAGGTTCGTGGAAGCCGAGCTGGACGGTGATGAAAAATCAGTTGGTTCTTGGACGTGATTTG
ATCATGCGGTCAATGTCGTTCCAGGTTGCTTTTCTTTCCGCGGCCGCTGTGGCTGCACGATTTGGCACGGCATCCTTGGC
GGCCCACCAGGTGTTGCTTCAGCTGTGGAATTTCATCACATTGGTGCTGGATTCTCTAGCTATCGCGGCGCAGACCTTAA
CTGGTGCAGCCCTGGGCGCTGGAACTGCGAAGGTCGCCCGCAGGGTGGGTAATCAGGTGATTAAGTACTCTCTGATTTTC
GCTGGTGGCTTAGGTTTGGTGTTCGTGGTCTTACACTCGTGGATTCCGCGTATTTTCACTCAGGACGCCGACGTTTTAGA
TGCGATTGCTTCCCCGTGGTGGATCATGGTCGCGATGATCATTTTGGGTGGCATTGTCTTTGCTATTGATGGTGTGCTGT
TGGGTGCTGCTGACGCGGTGTTCCTCCGAAATGCCTCTATCTTGGCGGTTGTGGTCGGATTCTTACCAGGCGTCTGGATT
TCCTATGCATTAGATGCAGGGCTGACAGGCGTGTGGTGTGGTTTGCTGGCGTTTATTCTGATCCGACTATTTGCGGTGAT
TTGGCGGTTTAAGTCTATGAAGTGGGCGCGTTAG

Upstream 100 bases:

>100_bases
CCTGCTGCAGGCTATACCGCTCGTGGTACGGAAATCGAAGCCCTCGATACGTTGATTGAAGCAACCGTTACCTTGGGGGA
GTCTTTGCGAAGCTCGGCGC

Downstream 100 bases:

>100_bases
CTTCGGCGCGTGGCAAACCACATTTGCTGGACTGCAGGCATAATGGACAAAGACTTTTAGCAACAACTATGTGGAGGTGA
CAGGTGACCACAACTCTGTG

Product: DNA-damage-inducible membrane protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSMSNNDFEHESHDVSAKQIFGLAFPALGVLAAMPLYLLLDTAVVGTLGGFELAALGAATTIQAQVTTQLTFLSYGTTAR
SSRIFGMGDRRGAIAEGVQATWVALFVGLGILTLMLIGAPTFALWLSGDEALAQEAGHWLRVAAFAVPLILMIMAGNGWL
RGIQNTKLPLYFTLAGVIPGAILIPIFVAKFGLVGSAWANLIAEAITASLFLGALIKHHEGSWKPSWTVMKNQLVLGRDL
IMRSMSFQVAFLSAAAVAARFGTASLAAHQVLLQLWNFITLVLDSLAIAAQTLTGAALGAGTAKVARRVGNQVIKYSLIF
AGGLGLVFVVLHSWIPRIFTQDADVLDAIASPWWIMVAMIILGGIVFAIDGVLLGAADAVFLRNASILAVVVGFLPGVWI
SYALDAGLTGVWCGLLAFILIRLFAVIWRFKSMKWAR

Sequences:

>Translated_437_residues
MSMSNNDFEHESHDVSAKQIFGLAFPALGVLAAMPLYLLLDTAVVGTLGGFELAALGAATTIQAQVTTQLTFLSYGTTAR
SSRIFGMGDRRGAIAEGVQATWVALFVGLGILTLMLIGAPTFALWLSGDEALAQEAGHWLRVAAFAVPLILMIMAGNGWL
RGIQNTKLPLYFTLAGVIPGAILIPIFVAKFGLVGSAWANLIAEAITASLFLGALIKHHEGSWKPSWTVMKNQLVLGRDL
IMRSMSFQVAFLSAAAVAARFGTASLAAHQVLLQLWNFITLVLDSLAIAAQTLTGAALGAGTAKVARRVGNQVIKYSLIF
AGGLGLVFVVLHSWIPRIFTQDADVLDAIASPWWIMVAMIILGGIVFAIDGVLLGAADAVFLRNASILAVVVGFLPGVWI
SYALDAGLTGVWCGLLAFILIRLFAVIWRFKSMKWAR
>Mature_436_residues
SMSNNDFEHESHDVSAKQIFGLAFPALGVLAAMPLYLLLDTAVVGTLGGFELAALGAATTIQAQVTTQLTFLSYGTTARS
SRIFGMGDRRGAIAEGVQATWVALFVGLGILTLMLIGAPTFALWLSGDEALAQEAGHWLRVAAFAVPLILMIMAGNGWLR
GIQNTKLPLYFTLAGVIPGAILIPIFVAKFGLVGSAWANLIAEAITASLFLGALIKHHEGSWKPSWTVMKNQLVLGRDLI
MRSMSFQVAFLSAAAVAARFGTASLAAHQVLLQLWNFITLVLDSLAIAAQTLTGAALGAGTAKVARRVGNQVIKYSLIFA
GGLGLVFVVLHSWIPRIFTQDADVLDAIASPWWIMVAMIILGGIVFAIDGVLLGAADAVFLRNASILAVVVGFLPGVWIS
YALDAGLTGVWCGLLAFILIRLFAVIWRFKSMKWAR

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=441, Percent_Identity=26.0770975056689, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46511; Mature: 46380

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSNNDFEHESHDVSAKQIFGLAFPALGVLAAMPLYLLLDTAVVGTLGGFELAALGAAT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHH
TIQAQVTTQLTFLSYGTTARSSRIFGMGDRRGAIAEGVQATWVALFVGLGILTLMLIGAP
EEEEHHHHEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TFALWLSGDEALAQEAGHWLRVAAFAVPLILMIMAGNGWLRGIQNTKLPLYFTLAGVIPG
CEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHCCH
AILIPIFVAKFGLVGSAWANLIAEAITASLFLGALIKHHEGSWKPSWTVMKNQLVLGRDL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHH
IMRSMSFQVAFLSAAAVAARFGTASLAAHQVLLQLWNFITLVLDSLAIAAQTLTGAALGA
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTAKVARRVGNQVIKYSLIFAGGLGLVFVVLHSWIPRIFTQDADVLDAIASPWWIMVAMI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHH
ILGGIVFAIDGVLLGAADAVFLRNASILAVVVGFLPGVWISYALDAGLTGVWCGLLAFIL
HHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRLFAVIWRFKSMKWAR
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SMSNNDFEHESHDVSAKQIFGLAFPALGVLAAMPLYLLLDTAVVGTLGGFELAALGAAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHH
TIQAQVTTQLTFLSYGTTARSSRIFGMGDRRGAIAEGVQATWVALFVGLGILTLMLIGAP
EEEEHHHHEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TFALWLSGDEALAQEAGHWLRVAAFAVPLILMIMAGNGWLRGIQNTKLPLYFTLAGVIPG
CEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHCCH
AILIPIFVAKFGLVGSAWANLIAEAITASLFLGALIKHHEGSWKPSWTVMKNQLVLGRDL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHH
IMRSMSFQVAFLSAAAVAARFGTASLAAHQVLLQLWNFITLVLDSLAIAAQTLTGAALGA
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTAKVARRVGNQVIKYSLIFAGGLGLVFVVLHSWIPRIFTQDADVLDAIASPWWIMVAMI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHH
ILGGIVFAIDGVLLGAADAVFLRNASILAVVVGFLPGVWISYALDAGLTGVWCGLLAFIL
HHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRLFAVIWRFKSMKWAR
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA