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The map label for this gene is gpsI [H]

Identifier: 62390815

GI number: 62390815

Start: 2052979

End: 2055240

Strand: Reverse

Name: gpsI [H]

Synonym: cg2166

Alternate gene names: 62390815

Gene position: 2055240-2052979 (Counterclockwise)

Preceding gene: 62390816

Following gene: 62390813

Centisome position: 62.61

GC content: 57.16

Gene sequence:

>2262_bases
ATGAGCGATGTAAAGTACTTCGAAGACACCGAATTTGGCCTGATCGAGGCCGTCGCAACCATCGACAACGGTGACTTCGG
AACCCGCACCATCCGTTTTGAAACCGGCCAACTTGCCCGCCAGGCAGATGGTGCAGTGACCACCTACCTCGACGATGACA
CGATGCTGCTGGCAACCACCACCGCATCCAACCAGCCACGCGAGGGCTTTGACTTCTTCCCACTGACCGTGGACGTTGAA
GAGCGTATGTACGCAGCTGGTCGCATCCCTGGCTCTTTCTTCCGTCGGGAGGGTCGCCCATCCACCGAAGCTATCCTGGC
TTGCCGTCTCATCGACCGCCCACTGCGCCCAACCTTTGTTAAGGGCCTGCGCAATGAGGTTCAGATCGTTGTCACCGTCA
TGTCCATGAACCCTGAGGATTACTACGATGTCGTAGCAATCAACGGAGCTTCCGCAGCAACCCGCATCTCCGGACTTCCT
GTCTCCGGCGCTGTCGGTGGCGTTCGCATGGCACTGGTTGTTGATGAAAAGCACCCAGAAGGCCAATGGGTTGCATTCCC
AACCCACGCTCAACATGAGCAGTCCGTATTTGAAATCGTTGTGGCTGGTCGCCTCGTCGAGCGCAAGCGCGGCAACAAGA
CCTTCTCCGACGTCGCAGTGATGATGGTGGAAGCTGGCGCTTCCGAAAACGTTGTCAACCGCGTCAAGGACGGTGCACCA
GCACCAACCGAAAAGATCGTCTCCGACGGCCTTGAAGCAGCTAAGCCATTCATCGACATCCTGTGCCGCGCACAGGAAGG
TCTGGCACAGCGCGTTGGAAACGCAGCCAAGGAATTCCCACTGTTCCCTCCATACACCGACGAGGTGTACTCCGCAGTGG
AGCGCAAGGTATCCAAGAAGCTAGCTTCTTTGCTGACCCTGAAGGCAAAGCAAGAGCGCGACGACGCTACCAACGCCTAC
ATGGAAGAAATCGAAGCCGAACTGCTTCCAAAGTTCGAGGCTTCCTACAGCTCAGCAGCTGAAGCGTCCAAGGAAATCCG
TGCAGGATACAACGCTGTCATGAAGGCCATCGTGCGCCGCATGATCCTCACCGATCACTTCCGCATCGACGGCCGCGGAG
TCACCGACATCCGTGACCTGGCAGTAGAAGTTGAGCTCATCCCACGTGCGCACGGTTCCTCCCTCTTCGAGCGTGGCGAG
ACCCAGATCCTTGGTGTCACCACCCTGGACATGCTCAAGATGGAACAGCAAATCGACTCCCTGGCACCAGGCGATGCGAA
GCGCTACATGCACCACTACAACTTCCCTCCATACTCCACCGGTGAAACCGGTCGTGTGGGCTCACCAAAGCGCCGCGAAA
TCGGCCACGGTGCACTTGCAGAACGCGCAGTTTTGCCAGTAATCCCATCCCGTGAGGAATTCCCATACGCAATCCGTCAG
GTCTCTGAAGCTCTGGGCTCCAACGGCTCCACCTCCATGGGCTCTGTCTGTGCATCCACTCTGTCCCTGTACAACGCTGG
TGTTCCACTGAAGGCACCTGTTGCAGGTATCGCCATGGGACTTGTTTCCGGTGAAATCGACGGCAAGACCGAGTACGTTG
CACTGACCGACATCCTCGGCGCAGAAGACGCATTCGGCGACATGGACTTCAAGGTTGCCGGCACCGCAGACTTCATCACC
GCACTTCAGCTGGACACCAAGCTGGACGGCATTCCTTCCAAGGTGCTCTCCGATGCGCTTGAGCAGGCACGCGATGCCCG
ACTGACCATCCTGAACACCATGGCTGATGTCATCAACGGACCTGATGAGATGAGCAAGTTCGCTCCTCGCATCACCACCG
TGAAGATCCCAGTGGCAAAGATCGGTGAGCTGATCGGACCAAAGGGTAAGAACATCAACGCTCTTACCGAAGAGACCGGC
GCAAACATCTCCATCGAAGATGACGGCACCGTGTTCATCTCTGCAGCTGACGGCGCATCTGCTGAAGCGGCGATCGAAAA
GATCAACGCTCTGGCGAACCCACAGCTGCCAAAGGTTGGCGAGCGCTTCCTCGGAACCGTCGTCAAGACCACCGCATTCG
GAGCATTCGTTTCCTTGCTCCCAGGCCGCGACGGCCTTGTTCACATCTCCAAGCTGGGTAACGGCAAGCGAGTAGAAAAG
GTCGACGATGTGGTGAAGGTTGGCGAGAAGATTCAGGTCGAAATCGCTGACATCGACAACCGCGGCAAGATCTCCTTGGT
CCCAGTTGTTGAAGAGGACTAA

Upstream 100 bases:

>100_bases
AGAGAACTGGTAAGGTTTTTACCGTTCTAGACCGCAGAAATCTTCGCGGCGACACCGATGATCGCCGAGCAGAACTAAAC
ATGAGGAGACCTACTCGCAT

Downstream 100 bases:

>100_bases
TTAGTTCTGGCTAGATCGGGCTAGATCGGGCTAAAAATAAATGTGGCGCTAAAACCTTATTGCGAGGTTTTAGCGCCACA
TTTTTCTATCTGTAGTTGAC

Product: polynucleotide phosphorylase/polyadenylase

Products: NA

Alternate protein names: Polynucleotide phosphorylase; PNPase [H]

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MSDVKYFEDTEFGLIEAVATIDNGDFGTRTIRFETGQLARQADGAVTTYLDDDTMLLATTTASNQPREGFDFFPLTVDVE
ERMYAAGRIPGSFFRREGRPSTEAILACRLIDRPLRPTFVKGLRNEVQIVVTVMSMNPEDYYDVVAINGASAATRISGLP
VSGAVGGVRMALVVDEKHPEGQWVAFPTHAQHEQSVFEIVVAGRLVERKRGNKTFSDVAVMMVEAGASENVVNRVKDGAP
APTEKIVSDGLEAAKPFIDILCRAQEGLAQRVGNAAKEFPLFPPYTDEVYSAVERKVSKKLASLLTLKAKQERDDATNAY
MEEIEAELLPKFEASYSSAAEASKEIRAGYNAVMKAIVRRMILTDHFRIDGRGVTDIRDLAVEVELIPRAHGSSLFERGE
TQILGVTTLDMLKMEQQIDSLAPGDAKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERAVLPVIPSREEFPYAIRQ
VSEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGEIDGKTEYVALTDILGAEDAFGDMDFKVAGTADFIT
ALQLDTKLDGIPSKVLSDALEQARDARLTILNTMADVINGPDEMSKFAPRITTVKIPVAKIGELIGPKGKNINALTEETG
ANISIEDDGTVFISAADGASAEAAIEKINALANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVEK
VDDVVKVGEKIQVEIADIDNRGKISLVPVVEED

Sequences:

>Translated_753_residues
MSDVKYFEDTEFGLIEAVATIDNGDFGTRTIRFETGQLARQADGAVTTYLDDDTMLLATTTASNQPREGFDFFPLTVDVE
ERMYAAGRIPGSFFRREGRPSTEAILACRLIDRPLRPTFVKGLRNEVQIVVTVMSMNPEDYYDVVAINGASAATRISGLP
VSGAVGGVRMALVVDEKHPEGQWVAFPTHAQHEQSVFEIVVAGRLVERKRGNKTFSDVAVMMVEAGASENVVNRVKDGAP
APTEKIVSDGLEAAKPFIDILCRAQEGLAQRVGNAAKEFPLFPPYTDEVYSAVERKVSKKLASLLTLKAKQERDDATNAY
MEEIEAELLPKFEASYSSAAEASKEIRAGYNAVMKAIVRRMILTDHFRIDGRGVTDIRDLAVEVELIPRAHGSSLFERGE
TQILGVTTLDMLKMEQQIDSLAPGDAKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERAVLPVIPSREEFPYAIRQ
VSEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGEIDGKTEYVALTDILGAEDAFGDMDFKVAGTADFIT
ALQLDTKLDGIPSKVLSDALEQARDARLTILNTMADVINGPDEMSKFAPRITTVKIPVAKIGELIGPKGKNINALTEETG
ANISIEDDGTVFISAADGASAEAAIEKINALANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVEK
VDDVVKVGEKIQVEIADIDNRGKISLVPVVEED
>Mature_752_residues
SDVKYFEDTEFGLIEAVATIDNGDFGTRTIRFETGQLARQADGAVTTYLDDDTMLLATTTASNQPREGFDFFPLTVDVEE
RMYAAGRIPGSFFRREGRPSTEAILACRLIDRPLRPTFVKGLRNEVQIVVTVMSMNPEDYYDVVAINGASAATRISGLPV
SGAVGGVRMALVVDEKHPEGQWVAFPTHAQHEQSVFEIVVAGRLVERKRGNKTFSDVAVMMVEAGASENVVNRVKDGAPA
PTEKIVSDGLEAAKPFIDILCRAQEGLAQRVGNAAKEFPLFPPYTDEVYSAVERKVSKKLASLLTLKAKQERDDATNAYM
EEIEAELLPKFEASYSSAAEASKEIRAGYNAVMKAIVRRMILTDHFRIDGRGVTDIRDLAVEVELIPRAHGSSLFERGET
QILGVTTLDMLKMEQQIDSLAPGDAKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERAVLPVIPSREEFPYAIRQV
SEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGEIDGKTEYVALTDILGAEDAFGDMDFKVAGTADFITA
LQLDTKLDGIPSKVLSDALEQARDARLTILNTMADVINGPDEMSKFAPRITTVKIPVAKIGELIGPKGKNINALTEETGA
NISIEDDGTVFISAADGASAEAAIEKINALANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVEKV
DDVVKVGEKIQVEIADIDNRGKISLVPVVEED

Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction [H]

COG id: COG1185

COG function: function code J; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI188528628, Length=729, Percent_Identity=34.8422496570645, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI145693187, Length=728, Percent_Identity=43.8186813186813, Blast_Score=532, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI115534063, Length=747, Percent_Identity=30.1204819277108, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI281362905, Length=722, Percent_Identity=34.6260387811634, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24651641, Length=722, Percent_Identity=34.6260387811634, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24651643, Length=722, Percent_Identity=34.6260387811634, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI161079377, Length=667, Percent_Identity=34.4827586206897, Blast_Score=344, Evalue=1e-94,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1000 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 3328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001247
- InterPro:   IPR015847
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR012162
- InterPro:   IPR015848
- InterPro:   IPR014069
- InterPro:   IPR003029
- InterPro:   IPR020568
- InterPro:   IPR022967 [H]

Pfam domain/function: PF00013 KH_1; PF03726 PNPase; PF01138 RNase_PH; PF03725 RNase_PH_C; PF00575 S1 [H]

EC number: =2.7.7.8 [H]

Molecular weight: Translated: 81272; Mature: 81141

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVKYFEDTEFGLIEAVATIDNGDFGTRTIRFETGQLARQADGAVTTYLDDDTMLLATT
CCCCCCCCCCCCHHHHHHEECCCCCCCCEEEEEECHHHHHHCCCCEEEEECCCEEEEEEE
TASNQPREGFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTEAILACRLIDRPLRPTFV
CCCCCCCCCCCEEEEEEEHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
KGLRNEVQIVVTVMSMNPEDYYDVVAINGASAATRISGLPVSGAVGGVRMALVVDEKHPE
HHHCCCEEEEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCCCCCCCEEEEEEEECCCCC
GQWVAFPTHAQHEQSVFEIVVAGRLVERKRGNKTFSDVAVMMVEAGASENVVNRVKDGAP
CCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCC
APTEKIVSDGLEAAKPFIDILCRAQEGLAQRVGNAAKEFPLFPPYTDEVYSAVERKVSKK
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LASLLTLKAKQERDDATNAYMEEIEAELLPKFEASYSSAAEASKEIRAGYNAVMKAIVRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MILTDHFRIDGRGVTDIRDLAVEVELIPRAHGSSLFERGETQILGVTTLDMLKMEQQIDS
HHHHHCEEECCCCCCHHHHHEEEEEEECCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHH
LAPGDAKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERAVLPVIPSREEFPYAIRQ
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHH
VSEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGEIDGKTEYVALTDILG
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHHC
AEDAFGDMDFKVAGTADFITALQLDTKLDGIPSKVLSDALEQARDARLTILNTMADVING
CCCCCCCCCEEEECCHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDEMSKFAPRITTVKIPVAKIGELIGPKGKNINALTEETGANISIEDDGTVFISAADGAS
HHHHHHHCCCEEEEEECHHHHHHHHCCCCCCCCHHHHCCCCEEEEECCCEEEEEECCCCC
AEAAIEKINALANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVEK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
VDDVVKVGEKIQVEIADIDNRGKISLVPVVEED
HHHHHHCCCEEEEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure 
SDVKYFEDTEFGLIEAVATIDNGDFGTRTIRFETGQLARQADGAVTTYLDDDTMLLATT
CCCCCCCCCCCHHHHHHEECCCCCCCCEEEEEECHHHHHHCCCCEEEEECCCEEEEEEE
TASNQPREGFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTEAILACRLIDRPLRPTFV
CCCCCCCCCCCEEEEEEEHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
KGLRNEVQIVVTVMSMNPEDYYDVVAINGASAATRISGLPVSGAVGGVRMALVVDEKHPE
HHHCCCEEEEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCCCCCCCEEEEEEEECCCCC
GQWVAFPTHAQHEQSVFEIVVAGRLVERKRGNKTFSDVAVMMVEAGASENVVNRVKDGAP
CCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCC
APTEKIVSDGLEAAKPFIDILCRAQEGLAQRVGNAAKEFPLFPPYTDEVYSAVERKVSKK
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LASLLTLKAKQERDDATNAYMEEIEAELLPKFEASYSSAAEASKEIRAGYNAVMKAIVRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MILTDHFRIDGRGVTDIRDLAVEVELIPRAHGSSLFERGETQILGVTTLDMLKMEQQIDS
HHHHHCEEECCCCCCHHHHHEEEEEEECCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHH
LAPGDAKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERAVLPVIPSREEFPYAIRQ
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHH
VSEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGEIDGKTEYVALTDILG
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHHC
AEDAFGDMDFKVAGTADFITALQLDTKLDGIPSKVLSDALEQARDARLTILNTMADVING
CCCCCCCCCEEEECCHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDEMSKFAPRITTVKIPVAKIGELIGPKGKNINALTEETGANISIEDDGTVFISAADGAS
HHHHHHHCCCEEEEEECHHHHHHHHCCCCCCCCHHHHCCCCEEEEECCCEEEEEECCCCC
AEAAIEKINALANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVEK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
VDDVVKVGEKIQVEIADIDNRGKISLVPVVEED
HHHHHHCCCEEEEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA