Click here to switch to the map view.

The map label for this gene is pgsA2 [H]

Identifier: 62390804

GI number: 62390804

Start: 2040565

End: 2041191

Strand: Reverse

Name: pgsA2 [H]

Synonym: cg2154

Alternate gene names: 62390804

Gene position: 2041191-2040565 (Counterclockwise)

Preceding gene: 62390807

Following gene: 62390803

Centisome position: 62.18

GC content: 51.67

Gene sequence:

>627_bases
GTGCAGGTAGGGTGGAACACCGTGAGTGATGTATCAGCAGGCGTAAATGGCGCACAAGATCCAAGCAATCAAGCGGTCAA
GCCTTCCAACTGGAACCTTCCGAACTTCTTGACCAGCTTGCGTATCATTGTCATCCCTTTGTTTGCGTGGCTTACGCTTA
AAGGTGAGACGGAAAACAATGCTTTTGCCTGGTGGGCGTTGGTTGTTTTCATTTTGCTCATGATCACCGACAAGCTTGAC
GGCGATATTGCGCGAGCACGTGGCCTGGTCACTGACTTTGGCAAGATCGCGGATCCGATTGCCGATAAGGCGTTGATGAC
CACAGCATTTGTCTGTTTCAACATCATCGGCATTTTGCCCTGGTGGGTCACTGCGTTGATTGTGCTTCGAGAGTTCGGCA
TTACCATCTGGCGTTTCTTCCAACTGCGCGCTGGAAATGTTGTGCCTGCATCAAAGGGGGGCAAGCTTAAGACTGCTCTG
CAGACTGTTGCCGTTGCTCTGTATCTGTGCCCTTTCCCAAGTTGGATGGATATTCCAAGCCAGATCGTCATGTATGCAGC
GCTGATCGTCACCGTGGTCACGGGTCTGCAGTACCTGTGGGATTCACGAAAGTCCGCAGAAAGCTAG

Upstream 100 bases:

>100_bases
TGGCGCTTCGTCCGTCGAGAGGTTTTTAGGAATAGAGTGGGCTCAAGCTTTGTGACAAGTTTTTTGGAGAAATCATTACT
AGTCGTAGTCTTCAATTTGG

Downstream 100 bases:

>100_bases
ACCATGTCGGAGAATCTGGCGGGGCGAGTGGTGGAGCTGTTGAAATCGCGCGGTGAAACGCTGGCGTTTTGTGAATCCCT
CACCGCCGGCCTTGCCAGTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MQVGWNTVSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWALVVFILLMITDKLD
GDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTAL
QTVAVALYLCPFPSWMDIPSQIVMYAALIVTVVTGLQYLWDSRKSAES

Sequences:

>Translated_208_residues
MQVGWNTVSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWALVVFILLMITDKLD
GDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTAL
QTVAVALYLCPFPSWMDIPSQIVMYAALIVTVVTGLQYLWDSRKSAES
>Mature_208_residues
MQVGWNTVSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWALVVFILLMITDKLD
GDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTAL
QTVAVALYLCPFPSWMDIPSQIVMYAALIVTVVTGLQYLWDSRKSAES

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=177, Percent_Identity=33.8983050847458, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984838, Length=209, Percent_Identity=27.7511961722488, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71984834, Length=176, Percent_Identity=28.9772727272727, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22962; Mature: 22962

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVGWNTVSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENN
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AFAWWALVVFILLMITDKLDGDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVALYLCPFPSWMDIPS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCHH
QIVMYAALIVTVVTGLQYLWDSRKSAES
HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQVGWNTVSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENN
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AFAWWALVVFILLMITDKLDGDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVALYLCPFPSWMDIPS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCHH
QIVMYAALIVTVVTGLQYLWDSRKSAES
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]