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The map label for this gene is nrdR [H]

Identifier: 62390768

GI number: 62390768

Start: 2005476

End: 2005928

Strand: Reverse

Name: nrdR [H]

Synonym: cg2112

Alternate gene names: 62390768

Gene position: 2005928-2005476 (Counterclockwise)

Preceding gene: 62390769

Following gene: 62390766

Centisome position: 61.11

GC content: 51.88

Gene sequence:

>453_bases
GTGTACTGCCCATTTTGCCAACATGATCATTCAAAAGTCATTGACTCCCGCGTCATTGACGCCGGAAGCGCCATTCGCAG
GCGCCGCGAGTGCAGCAAATGCGAAGGCCGTTTCACCACCATCGAAAAAGCTGTTCTCCTCGTTGTTAAAAGAAACGGCG
TCACTGAACCGTTCAGTCGAGAAAAAGTAGTCACCGGTGTCCGTCGTGCATGCCAAGGCCGCGACGTATCAGATGACGCG
TTGAAACGCCTAGCTCAGCAAGTGGAAGAAACAGTCCGCAGCAACGGAAGCTCTCAAGTACGCGCTAACGATATTGGTTT
AGCCATTCTCGATCCACTGAGAGAACTCGACGAGGTAGCGTACCTACGCTTTGCCTCTGTGTATAAGTCTTTTGACAGTG
CTGACGACTTTGAAAAAGAAATCCGCCTCATGCGCAGACGCGGAAGGGACTAG

Upstream 100 bases:

>100_bases
TAGATCAATGCTGGCATAAACTAAAGGCACAACAGCCGATTCACTTATTTTTAGGCGAATGCTTGAAGTCGAAGTAAGTG
AGGGGGAGAGGATCCGGTTA

Downstream 100 bases:

>100_bases
CAGACACAAAGTCTTAACTAGTCCCTCATCTCAAGCAGTGCTTATCGAAGCTTGGCAATAGCCTTCTGGATTCTCTGCGC
CGATACAGGTCGGGGAGTGC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MYCPFCQHDHSKVIDSRVIDAGSAIRRRRECSKCEGRFTTIEKAVLLVVKRNGVTEPFSREKVVTGVRRACQGRDVSDDA
LKRLAQQVEETVRSNGSSQVRANDIGLAILDPLRELDEVAYLRFASVYKSFDSADDFEKEIRLMRRRGRD

Sequences:

>Translated_150_residues
MYCPFCQHDHSKVIDSRVIDAGSAIRRRRECSKCEGRFTTIEKAVLLVVKRNGVTEPFSREKVVTGVRRACQGRDVSDDA
LKRLAQQVEETVRSNGSSQVRANDIGLAILDPLRELDEVAYLRFASVYKSFDSADDFEKEIRLMRRRGRD
>Mature_150_residues
MYCPFCQHDHSKVIDSRVIDAGSAIRRRRECSKCEGRFTTIEKAVLLVVKRNGVTEPFSREKVVTGVRRACQGRDVSDDA
LKRLAQQVEETVRSNGSSQVRANDIGLAILDPLRELDEVAYLRFASVYKSFDSADDFEKEIRLMRRRGRD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=45.1388888888889, Blast_Score=127, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17139; Mature: 17139

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCPFCQHDHSKVIDSRVIDAGSAIRRRRECSKCEGRFTTIEKAVLLVVKRNGVTEPFSR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHH
EKVVTGVRRACQGRDVSDDALKRLAQQVEETVRSNGSSQVRANDIGLAILDPLRELDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHCCHHHHHHHHHHHHHH
YLRFASVYKSFDSADDFEKEIRLMRRRGRD
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYCPFCQHDHSKVIDSRVIDAGSAIRRRRECSKCEGRFTTIEKAVLLVVKRNGVTEPFSR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHH
EKVVTGVRRACQGRDVSDDALKRLAQQVEETVRSNGSSQVRANDIGLAILDPLRELDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHCCHHHHHHHHHHHHHH
YLRFASVYKSFDSADDFEKEIRLMRRRGRD
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]