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The map label for this gene is pimA [H]

Identifier: 62390548

GI number: 62390548

Start: 1768417

End: 1769502

Strand: Reverse

Name: pimA [H]

Synonym: cg1876

Alternate gene names: 62390548

Gene position: 1769502-1768417 (Counterclockwise)

Preceding gene: 62390549

Following gene: 62390547

Centisome position: 53.9

GC content: 58.84

Gene sequence:

>1086_bases
GTGCGAATTGGAATGGTCTGCCCGTACTCCTTCGATGAGCCGGGCGGTGTTCAAGCGCATATCCTTGACTTAGCGCGAAC
CTTCATTGCCCAAGGCCATGAGGTTCAGGTGCTTGGTCCGTGTAGTGCGGATACGCAGGTGCCCGATTTCGTGGTGCGCG
GTGGTGGCAGCATCCCGATTCCGTACAATGGCTCGGTTGCCCGCTTGAGCTTTGGGCCGAAAATGTTCAAGGCCGTGCGC
ACGTTCCTCCGCGAAGGCAACTTCGATGTGCTGCATATCCATGAACCGAATTCACCAAGTTTTTCCATGGCGGCGCTACG
CTTTGCGGAAGGCCCCATCGTTGCTACTTACCACGCCTCCAGTAGCGGATCGAAGCTGCTCAAGGCTTTCTTACCAGTGC
TTTCGCCCATGCTGGAGAAAGTGCGCGCAGGCATCGCCGTGTCTGAAATGGCTCGGCGCTGGCAGGTGGAGCAAGTCGGC
GGCGATCCCGTGCTGATCCCCAACGGGGTAGAGACCTCCATGTTCAAAGCCGCGCGCCAAATCGAACCGAATGATCCTGT
AGAGATCGTCTTTTTGGGTCGCCTCGATGAGTCCCGCAAAGGCCTCGACATCCTCCTGCGCGCTCTGACCAGGCTGGATC
GCCCGTTTACCTGCACCGTCATTGGCGGCGGCACCCCGCGAGAAGTCGCCGGCATCAACTTTGTGGGCCGCGTCAGCGAT
GAGGAAAAGGCAGCAATCTTAGGTCGCGCAGACATCTATGTCGCACCCAACACCGGCGGCGAAAGCTTCGGCATCGTGCT
AGTTGAAGCGATGGCCGCGGGATGCGCTGTCGTCGCCAGCGACCTAGAAGCGTTCTCCCTGGTCACCGATTCTGAAGCCG
CACAGCCAGCGGGCGTGCTATTTAAAACCGGCTCAGACGCCGACCTAGCCAAAAAACTTCAAGCGCTTATCGACGACCCC
TCCTCCCGTTCCACGCTTATCGCCGCGGGGCTAAAGCGCGCAAACGCCTACGACTGGTCGACAGTATCCACCCAGGTCAT
GGCAGTCTATGAAACCATTGCGATCGACAAAGTGAGGCTTGGATGA

Upstream 100 bases:

>100_bases
CCAACCCCTGTGGTTTGGTGATTTGGATCCGGAGCGTCTCAAGCGCTCTAGGGAGCAGACAAATGTTCACAAACCGGTGG
CATTACAGGAGGACAATTAG

Downstream 100 bases:

>100_bases
CCCTTGTTTACCTCCTCATCGCTGTCGTTGTCACCGCAACTGTTCTGTGGGCGTATTTCACAGCACAACGCCTCAACCGG
CTCCACATCCGCACCGACTC

Product: glycosyl transferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MRIGMVCPYSFDEPGGVQAHILDLARTFIAQGHEVQVLGPCSADTQVPDFVVRGGGSIPIPYNGSVARLSFGPKMFKAVR
TFLREGNFDVLHIHEPNSPSFSMAALRFAEGPIVATYHASSSGSKLLKAFLPVLSPMLEKVRAGIAVSEMARRWQVEQVG
GDPVLIPNGVETSMFKAARQIEPNDPVEIVFLGRLDESRKGLDILLRALTRLDRPFTCTVIGGGTPREVAGINFVGRVSD
EEKAAILGRADIYVAPNTGGESFGIVLVEAMAAGCAVVASDLEAFSLVTDSEAAQPAGVLFKTGSDADLAKKLQALIDDP
SSRSTLIAAGLKRANAYDWSTVSTQVMAVYETIAIDKVRLG

Sequences:

>Translated_361_residues
MRIGMVCPYSFDEPGGVQAHILDLARTFIAQGHEVQVLGPCSADTQVPDFVVRGGGSIPIPYNGSVARLSFGPKMFKAVR
TFLREGNFDVLHIHEPNSPSFSMAALRFAEGPIVATYHASSSGSKLLKAFLPVLSPMLEKVRAGIAVSEMARRWQVEQVG
GDPVLIPNGVETSMFKAARQIEPNDPVEIVFLGRLDESRKGLDILLRALTRLDRPFTCTVIGGGTPREVAGINFVGRVSD
EEKAAILGRADIYVAPNTGGESFGIVLVEAMAAGCAVVASDLEAFSLVTDSEAAQPAGVLFKTGSDADLAKKLQALIDDP
SSRSTLIAAGLKRANAYDWSTVSTQVMAVYETIAIDKVRLG
>Mature_361_residues
MRIGMVCPYSFDEPGGVQAHILDLARTFIAQGHEVQVLGPCSADTQVPDFVVRGGGSIPIPYNGSVARLSFGPKMFKAVR
TFLREGNFDVLHIHEPNSPSFSMAALRFAEGPIVATYHASSSGSKLLKAFLPVLSPMLEKVRAGIAVSEMARRWQVEQVG
GDPVLIPNGVETSMFKAARQIEPNDPVEIVFLGRLDESRKGLDILLRALTRLDRPFTCTVIGGGTPREVAGINFVGRVSD
EEKAAILGRADIYVAPNTGGESFGIVLVEAMAAGCAVVASDLEAFSLVTDSEAAQPAGVLFKTGSDADLAKKLQALIDDP
SSRSTLIAAGLKRANAYDWSTVSTQVMAVYETIAIDKVRLG

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to pimB, the mannosyltransferase pim

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 38491; Mature: 38491

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGMVCPYSFDEPGGVQAHILDLARTFIAQGHEVQVLGPCSADTQVPDFVVRGGGSIPI
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCC
PYNGSVARLSFGPKMFKAVRTFLREGNFDVLHIHEPNSPSFSMAALRFAEGPIVATYHAS
CCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHEEEECCCCEEEEEECC
SSGSKLLKAFLPVLSPMLEKVRAGIAVSEMARRWQVEQVGGDPVLIPNGVETSMFKAARQ
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCEEEECCCCCHHHHHHHHH
IEPNDPVEIVFLGRLDESRKGLDILLRALTRLDRPFTCTVIGGGTPREVAGINFVGRVSD
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCC
EEKAAILGRADIYVAPNTGGESFGIVLVEAMAAGCAVVASDLEAFSLVTDSEAAQPAGVL
CCCEEEEECEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCEE
FKTGSDADLAKKLQALIDDPSSRSTLIAAGLKRANAYDWSTVSTQVMAVYETIAIDKVRL
EECCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEC
G
C
>Mature Secondary Structure
MRIGMVCPYSFDEPGGVQAHILDLARTFIAQGHEVQVLGPCSADTQVPDFVVRGGGSIPI
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCC
PYNGSVARLSFGPKMFKAVRTFLREGNFDVLHIHEPNSPSFSMAALRFAEGPIVATYHAS
CCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHEEEECCCCEEEEEECC
SSGSKLLKAFLPVLSPMLEKVRAGIAVSEMARRWQVEQVGGDPVLIPNGVETSMFKAARQ
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCEEEECCCCCHHHHHHHHH
IEPNDPVEIVFLGRLDESRKGLDILLRALTRLDRPFTCTVIGGGTPREVAGINFVGRVSD
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCC
EEKAAILGRADIYVAPNTGGESFGIVLVEAMAAGCAVVASDLEAFSLVTDSEAAQPAGVL
CCCEEEEECEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCEE
FKTGSDADLAKKLQALIDDPSSRSTLIAAGLKRANAYDWSTVSTQVMAVYETIAIDKVRL
EECCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12068013 [H]