Click here to switch to the map view.

The map label for this gene is ruvA [H]

Identifier: 62390542

GI number: 62390542

Start: 1763986

End: 1764606

Strand: Reverse

Name: ruvA [H]

Synonym: cg1870

Alternate gene names: 62390542

Gene position: 1764606-1763986 (Counterclockwise)

Preceding gene: 62390543

Following gene: 62390541

Centisome position: 53.75

GC content: 53.62

Gene sequence:

>621_bases
ATGATTGCCTCACTTCGTGGCACTGTTATCAACATTGGTCTGAGCTCTGCTGTCATTGAATGCAATGGCGTGGGCTATGA
GGTTGTCACCACACCGAACACCTTGTCACAGTTGGTCCGCGGTGAGGAAGCACTGGTGTTGACCACCATGGTGGTCCGCG
AAGACGCGATGAAACTCTATGGGTTTATTGACAATGAATCACGTGAGATGTTTTCCGTGTTGCAAACAGTATCTGGATTG
GGTCCACGCCTGGCCTTGGCATGTGAATCGGTGTTGAGCCCACTGGAGATTTCTCAGGCGATCACCAATGCCGATGCCAA
AACTTTGCAGCGGGTTCCGGGTGTGGGAAAGCGCATGGCAGATCGTCTCATCGTGGAGCTTAAAGGCAAGGTCGCAGCTT
TTGCTGCCGGTGTCGTGGATGAGGGAGGGGAGCAAATTTCCTTGCCTAACGCGAACATTGCTTCTGAGGTGGTTGTGGAG
CAGGTTTCTCAAGCGCTGGTGGGGTTGGGCTTTAGCGAGAAGCAATCAGATGATGCAGTGAGCTTTGTGCTGGCGGCGGA
TCCATCCTTGGACACCAGTGGCGCGCTTCGTGCCGCATTGGCAAAACTCAGCGGAAAGTAG

Upstream 100 bases:

>100_bases
TGCATCCGATCCTGCTAAAGCGGCTCATCCCAGTCAGTTTCAACGAACTGACACCAATTAGTTTTTAAAAAGTTCTAGTA
CATTTTTCAGGAGTGTCTTC

Downstream 100 bases:

>100_bases
ACCCTCATGTCCGATGTGGAAAGAACAGAGTTTGAAATTCCGGGAGGAATTCCACCTCGTCGAAACGGTGGTCAAGGCCG
TGCAGCTGATACCAACGTAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLYGFIDNESREMFSVLQTVSGL
GPRLALACESVLSPLEISQAITNADAKTLQRVPGVGKRMADRLIVELKGKVAAFAAGVVDEGGEQISLPNANIASEVVVE
QVSQALVGLGFSEKQSDDAVSFVLAADPSLDTSGALRAALAKLSGK

Sequences:

>Translated_206_residues
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLYGFIDNESREMFSVLQTVSGL
GPRLALACESVLSPLEISQAITNADAKTLQRVPGVGKRMADRLIVELKGKVAAFAAGVVDEGGEQISLPNANIASEVVVE
QVSQALVGLGFSEKQSDDAVSFVLAADPSLDTSGALRAALAKLSGK
>Mature_206_residues
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLYGFIDNESREMFSVLQTVSGL
GPRLALACESVLSPLEISQAITNADAKTLQRVPGVGKRMADRLIVELKGKVAAFAAGVVDEGGEQISLPNANIASEVVVE
QVSQALVGLGFSEKQSDDAVSFVLAADPSLDTSGALRAALAKLSGK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=35.9605911330049, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21477; Mature: 21477

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLY
CCCCCCCEEEEECCCCEEEEECCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GFIDNESREMFSVLQTVSGLGPRLALACESVLSPLEISQAITNADAKTLQRVPGVGKRMA
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHCCCCHHHHH
DRLIVELKGKVAAFAAGVVDEGGEQISLPNANIASEVVVEQVSQALVGLGFSEKQSDDAV
HHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
SFVLAADPSLDTSGALRAALAKLSGK
EEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIASLRGTVINIGLSSAVIECNGVGYEVVTTPNTLSQLVRGEEALVLTTMVVREDAMKLY
CCCCCCCEEEEECCCCEEEEECCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GFIDNESREMFSVLQTVSGLGPRLALACESVLSPLEISQAITNADAKTLQRVPGVGKRMA
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHCCCCHHHHH
DRLIVELKGKVAAFAAGVVDEGGEQISLPNANIASEVVVEQVSQALVGLGFSEKQSDDAV
HHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCE
SFVLAADPSLDTSGALRAALAKLSGK
EEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA