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The map label for this gene is aroC

Identifier: 62390506

GI number: 62390506

Start: 1721135

End: 1722367

Strand: Reverse

Name: aroC

Synonym: cg1829

Alternate gene names: 62390506

Gene position: 1722367-1721135 (Counterclockwise)

Preceding gene: 62390507

Following gene: 62390505

Centisome position: 52.47

GC content: 56.61

Gene sequence:

>1233_bases
ATGCTAGGCATGCTTCGATGGACTACAGCAGGTGAATCCCACGGCCAGGCGCTTATCGCCACGGTTGAACACATGCCAGC
AGGCGTGCCCGTGACTAAAGATGAGGTCTCGTATCAATTGGCGCGCCGACGCCTTGGATATGGTCGCGGCGCTCGCATGA
AGTTTGAGCAAGACGCGTTGACCTTCCTCACCGGCATCCGCCACGGCCTCACTTTGGGTAGCCCCATCTCAATCATGATC
GGCAACACTGAGTGGGATAAGTGGACCACCATCATGTCCTCTGACGCTTTGGACATGGAAGACCCAGATAACGTTGCGGC
GATGTCTTCGGGTCGGGGCGCAAAACTGACTCGTCCGCGTCCAGGCCACGCTGATTACGCAGGCATGCTCAAGTACGGAT
TCGATGATGCCCGCAACGTGCTGGAGCGTTCTTCAGCCCGTGAGACGGCAGCACGCGTGGCAGCAGCAACCGTTGCGCGT
TCCTTCCTGCGTGAAACCTTGGGCGTGGAAGTGCTTTCCCACGTAATTTCCATTGGTGCGTCCGAGCCTTACACTGGCGC
GGAGCCAACCTTTGCAGATATTCAAGCAATCGATGATTCCCCAGTTCGTGCATTCGGTAAAGACGCTGAAGAATCCATGA
TCGCGGAAATCGAGGCCGCAAAGAAAGCCGGCGATACCCTCGGTGGCATCGTGGAAGTGATTGTTGAAGGCCTGCCCATC
GGTTTGGGCTCACACATTTCTGGCGAAGATCGCCTCGATGCGCAGATCGCAGCTGCACTCATGGGCATTCAGGCCATCAA
GGGCGTGGAAATCGGTGACGGTTTCGAAGAAGCTCGTCGACGTGGCTCCGAAGCCCACGATGAAGTGTTCCTGGATGACA
ACGGCGTATACCGCAACACCAACCGTGCAGGTGGCCTCGAAGGCGGCATGACCAACGGTGAAACCCTGCGCGTTCGTGCT
GGCATGAAGCCAATTTCTACTGTGCCTCGCGCCCTGAAAACCATTGATATGGAAAACGGCAAGGCAGCAACCGGAATCCA
CCAGCGTTCCGACGTGTGCGCTGTTCCAGCCGCCGGTGTCGTTGCAGAAGCAATGGTCACCCTGGTTCTCGCCCGCGCAG
TCCTGCAGAAATTCGGCGGTGACTCCCTGAGCGAAACCAAGAGCAACATTGACACCTACCTCAAAAACATTGAGGAACGA
ATGAAATTCGAAGGTTTAGAGGATGGAGCGTAA

Upstream 100 bases:

>100_bases
CGCTAGTGCCTGCAGTTATGTCGCTTTTTGACGTCGAAAAGCAATTTTAAAAAGCCCTTGGGGTGGGCTGGATACGTCTT
CTGCGGCCTTTCGTGCGATA

Downstream 100 bases:

>100_bases
TGAAGTGAATGATCAAATTCACTTAGATCATCAATCAGATGACACCTCTGAATGCTCCTGCCCGATCGTGGTTCTTGTGG
GTTTGCCAGGAGCTGGAAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMI
GNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVAR
SFLRETLGVEVLSHVISIGASEPYTGAEPTFADIQAIDDSPVRAFGKDAEESMIAEIEAAKKAGDTLGGIVEVIVEGLPI
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRA
GMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEER
MKFEGLEDGA

Sequences:

>Translated_410_residues
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMI
GNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVAR
SFLRETLGVEVLSHVISIGASEPYTGAEPTFADIQAIDDSPVRAFGKDAEESMIAEIEAAKKAGDTLGGIVEVIVEGLPI
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRA
GMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEER
MKFEGLEDGA
>Mature_410_residues
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMI
GNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVAR
SFLRETLGVEVLSHVISIGASEPYTGAEPTFADIQAIDDSPVRAFGKDAEESMIAEIEAAKKAGDTLGGIVEVIVEGLPI
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRA
GMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEER
MKFEGLEDGA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=374, Percent_Identity=34.4919786096257, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321290, Length=382, Percent_Identity=31.9371727748691, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CORGL (Q9X5D0)

Other databases:

- EMBL:   AF124600
- EMBL:   BA000036
- EMBL:   BX927152
- RefSeq:   NP_600837.1
- RefSeq:   YP_225908.1
- ProteinModelPortal:   Q9X5D0
- SMR:   Q9X5D0
- GeneID:   1019592
- GeneID:   3343477
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg1829
- KEGG:   cgl:NCgl1561
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   CGLU196627:CG1829-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 43734; Mature: 43734

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDAL
CCCCEEECCCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHH
TFLTGIRHGLTLGSPISIMIGNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPR
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCC
PGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVARSFLRETLGVEVLSHVISIGA
CCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEPYTGAEPTFADIQAIDDSPVRAFGKDAEESMIAEIEAAKKAGDTLGGIVEVIVEGLPI
CCCCCCCCCCHHHHEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEECCCCCEECC
NRAGGLEGGMTNGETLRVRAGMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGV
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
VAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEERMKFEGLEDGA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDAL
CCCCEEECCCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHH
TFLTGIRHGLTLGSPISIMIGNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPR
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCC
PGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVARSFLRETLGVEVLSHVISIGA
CCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEPYTGAEPTFADIQAIDDSPVRAFGKDAEESMIAEIEAAKKAGDTLGGIVEVIVEGLPI
CCCCCCCCCCHHHHEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEECCCCCEECC
NRAGGLEGGMTNGETLRVRAGMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGV
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
VAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEERMKFEGLEDGA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626