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The map label for this gene is tkt [H]

Identifier: 62390456

GI number: 62390456

Start: 1665870

End: 1667972

Strand: Direct

Name: tkt [H]

Synonym: cg1774

Alternate gene names: 62390456

Gene position: 1665870-1667972 (Clockwise)

Preceding gene: 62390454

Following gene: 62390457

Centisome position: 50.75

GC content: 58.49

Gene sequence:

>2103_bases
TTGACCACCTTGACGCTGTCACCTGAACTTCAGGCGCTCACTGTACGCAATTACCCCTCTGATTGGTCCGATGTGGACAC
CAAGGCTGTAGACACTGTTCGTGTCCTCGCTGCAGACGCTGTAGAAAACTGTGGCTCCGGCCACCCAGGCACCGCAATGA
GCCTGGCTCCCCTTGCATACACCTTGTACCAGCGGGTTATGAACGTAGATCCACAGGACACCAACTGGGCAGGCCGTGAC
CGCTTCGTTCTTTCTTGTGGCCACTCCTCTTTGACCCAGTACATCCAGCTTTACTTGGGTGGATTCGGCCTTGAGATGGA
TGACCTGAAGGCTCTGCGCACCTGGGATTCCTTGACCCCAGGACACCCTGAGTACCGCCACACCAAGGGCGTTGAGATCA
CCACTGGCCCTCTTGGCCAGGGTCTTGCATCTGCAGTTGGTATGGCCATGGCTGCTCGTCGTGAGCGTGGCCTATTCGAC
CCAACCGCTGCTGAGGGCGAATCCCCATTCGACCACCACATCTACGTCATTGCTTCTGATGGTGACCTGCAGGAAGGTGT
CACCTCTGAGGCATCCTCCATCGCTGGCACCCAGCAGCTGGGCAACCTCATCGTGTTCTGGGATGACAACCGCATCTCCA
TCGAAGACAACACTGAGATCGCTTTCAACGAGGACGTTGTTGCTCGTTACAAGGCTTACGGCTGGCAGACCATTGAGGTT
GAGGCTGGCGAGGACGTTGCAGCAATCGAAGCTGCAGTGGCTGAGGCTAAGAAGGACACCAAGCGACCTACCTTCATCCG
CGTTCGCACCATCATCGGCTTCCCAGCTCCAACTATGATGAACACCGGTGCTGTGCACGGTGCTGCTCTTGGCGCAGCTG
AGGTTGCAGCAACCAAGACTGAGCTTGGATTCGATCCTGAGGCTCACTTCGCGATCGACGATGAGGTTATCGCTCACACC
CGCTCCCTCGCAGAGCGCGCTGCACAGAAGAAGGCTGCATGGCAGGTCAAGTTCGATGAGTGGGCAGCTGCCAACCCTGA
GAACAAGGCTCTGTTCGATCGCCTGAACTCCCGTGAGCTTCCAGCGGGCTACGCTGACGAGCTCCCAACATGGGATGCAG
ATGAGAAGGGCGTCGCAACTCGTAAGGCTTCCGAGGCTGCACTTCAGGCACTGGGCAAGACCCTTCCTGAGCTGTGGGGC
GGTTCCGCTGACCTCGCAGGTTCCAACAACACCGTGATCAAGGGCTCCCCTTCCTTCGGCCCTGAGTCCATCTCCACCGA
GACCTGGTCTGCTGAGCCTTACGGCCGTAACCTGCACTTCGGTATCCGTGAGCACGCTATGGGATCCATCCTCAACGGCA
TTTCCCTCCACGGTGGCACCCGCCCATACGGCGGAACCTTCCTCATCTTCTCCGACTACATGCGTCCTGCAGTTCGTCTT
GCAGCTCTCATGGAGACCGACGCTTACTACGTCTGGACCCACGACTCCATCGGTCTGGGCGAAGATGGCCCAACCCACCA
GCCTGTTGAAACCTTGGCTGCACTGCGCGCCATCCCAGGTCTGTCCGTCCTGCGTCCTGCAGATGCGAACGAGACCGCCC
AGGCTTGGGCTGCAGCACTTGAGTACAAGGAAGGCCCTAAGGGTCTTGCACTGACCCGCCAGAACGTTCCTGTTCTGGAA
GGCACCAAGGAGAAGGCTGCTGAAGGCGTTCGCCGCGGTGGCTACGTCCTGGTTGAGGGTTCCAAGGAAACCCCAGATGT
GATCCTCATGGGCTCCGGCTCCGAGGTTCAGCTTGCAGTTAACGCTGCGAAGGCTCTGGAAGCTGAGGGCGTTGCAGCTC
GCGTTGTTTCCGTTCCTTGCATGGATTGGTTCCAGGAGCAGGACGCAGAGTACATCGAGTCCGTTCTGCCTGCAGCTGTG
ACCGCTCGTGTGTCTGTTGAAGCTGGCATCGCAATGCCTTGGTACCGCTTCTTGGGCACCCAGGGCCGTGCTGTCTCCCT
TGAGCACTTCGGTGCTTCTGCGGATTACCAGACCCTGTTTGAGAAGTTCGGCATCACCACCGATGCAGTCGTGGCAGCGG
CCAAGGACTCCATTAACGGTTAA

Upstream 100 bases:

>100_bases
CCTTTGCCAAATTTGAACCAATTAACCTAAGTCGTAGATCTGATCATCGGATCTAACGAAAACGAACCAAAACTTTGGTC
CCGGTTTAACCCAGGAAGGA

Downstream 100 bases:

>100_bases
TTGCCCTGCTGTTTTTAGCTTCAACCCGGGGCAATATGATTCTCCGGAATTTTATTGCCCCGGGTTGTTGTTGTTAATCG
GTACAAAGGGTCTTAAGCAC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MTTLTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVMNVDPQDTNWAGRD
RFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFD
PTAAEGESPFDHHIYVIASDGDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEV
EAGEDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELGFDPEAHFAIDDEVIAHT
RSLAERAAQKKAAWQVKFDEWAAANPENKALFDRLNSRELPAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWG
GSADLAGSNNTVIKGSPSFGPESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRL
AALMETDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYKEGPKGLALTRQNVPVLE
GTKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAV
TARVSVEAGIAMPWYRFLGTQGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING

Sequences:

>Translated_700_residues
MTTLTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVMNVDPQDTNWAGRD
RFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFD
PTAAEGESPFDHHIYVIASDGDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEV
EAGEDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELGFDPEAHFAIDDEVIAHT
RSLAERAAQKKAAWQVKFDEWAAANPENKALFDRLNSRELPAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWG
GSADLAGSNNTVIKGSPSFGPESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRL
AALMETDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYKEGPKGLALTRQNVPVLE
GTKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAV
TARVSVEAGIAMPWYRFLGTQGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING
>Mature_699_residues
TTLTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVMNVDPQDTNWAGRDR
FVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDP
TAAEGESPFDHHIYVIASDGDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEVE
AGEDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELGFDPEAHFAIDDEVIAHTR
SLAERAAQKKAAWQVKFDEWAAANPENKALFDRLNSRELPAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWGG
SADLAGSNNTVIKGSPSFGPESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRLA
ALMETDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYKEGPKGLALTRQNVPVLEG
TKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVT
ARVSVEAGIAMPWYRFLGTQGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=589, Percent_Identity=27.1646859083192, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI4507521, Length=589, Percent_Identity=27.1646859083192, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI133778974, Length=683, Percent_Identity=24.1581259150805, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI48994911, Length=670, Percent_Identity=46.5671641791045, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1788808, Length=671, Percent_Identity=44.4113263785395, Blast_Score=519, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17539652, Length=679, Percent_Identity=25.920471281296, Blast_Score=149, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=682, Percent_Identity=44.2815249266862, Blast_Score=536, Evalue=1e-153,
Organism=Saccharomyces cerevisiae, GI6319593, Length=684, Percent_Identity=44.0058479532164, Blast_Score=523, Evalue=1e-149,
Organism=Drosophila melanogaster, GI45551847, Length=588, Percent_Identity=26.1904761904762, Blast_Score=152, Evalue=8e-37,
Organism=Drosophila melanogaster, GI45550715, Length=588, Percent_Identity=26.1904761904762, Blast_Score=152, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24645119, Length=541, Percent_Identity=26.9870609981516, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24666278, Length=590, Percent_Identity=25.4237288135593, Blast_Score=136, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 75096; Mature: 74964

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAY
CCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TLYQRVMNVDPQDTNWAGRDRFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTP
HHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
GHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAAEGESPFDHHIYVIASD
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
GDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEV
CCCHHCCHHHHHHHHCHHHHCCEEEEECCCEEEECCCCEEEECCHHHHHHHHCCCEEEEE
EAGEDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKT
ECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHCCCCCCCHHHHCHHHHHHHHH
ELGFDPEAHFAIDDEVIAHTRSLAERAAQKKAAWQVKFDEWAAANPENKALFDRLNSREL
HCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCHHHHHHCCCCCC
PAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSADLAGSNNTVIKGSPSFG
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
PESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCEEEEEHHHHHHHHHH
AALMETDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAAL
HHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHH
EYKEGPKGLALTRQNVPVLEGTKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAV
HHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCEEEEEE
NAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTARVSVEAGIAMPWYRFLGT
EHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCC
QGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING
CCCEEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTLTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAY
CEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TLYQRVMNVDPQDTNWAGRDRFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTP
HHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
GHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAAEGESPFDHHIYVIASD
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
GDLQEGVTSEASSIAGTQQLGNLIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEV
CCCHHCCHHHHHHHHCHHHHCCEEEEECCCEEEECCCCEEEECCHHHHHHHHCCCEEEEE
EAGEDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKT
ECCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHCCCCCCCHHHHCHHHHHHHHH
ELGFDPEAHFAIDDEVIAHTRSLAERAAQKKAAWQVKFDEWAAANPENKALFDRLNSREL
HCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCHHHHHHCCCCCC
PAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSADLAGSNNTVIKGSPSFG
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCC
PESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCEEEEEHHHHHHHHHH
AALMETDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAAL
HHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHH
EYKEGPKGLALTRQNVPVLEGTKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAV
HHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCEEEEEE
NAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTARVSVEAGIAMPWYRFLGT
EHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCC
QGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING
CCCEEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]