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The map label for this gene is tetA [H]

Identifier: 62390408

GI number: 62390408

Start: 1609125

End: 1610714

Strand: Reverse

Name: tetA [H]

Synonym: cg1720

Alternate gene names: 62390408

Gene position: 1610714-1609125 (Counterclockwise)

Preceding gene: 62390410

Following gene: 62390407

Centisome position: 49.07

GC content: 54.21

Gene sequence:

>1590_bases
ATGCGCACATGGTCCTGGTTTGTTCCGGATTCTCCAGATGAGGGCACACCCTTGCTTCCCAAGTTGGAGAACTCCACGCC
AGTTAAAAGTGCTTGGGCGTTACTGTGGGCGTTTCCTGCTGCTACGTGGCTGTTGGTATTCGGCATGTTGGTGTCCAGCA
TGTTTGGTGCTGTGGTGTCGCTGGTGGTTGGGCGTGGCTCGGAATGGGCGTTTGGCTCAGGTGAGTTGATGCCAGTACTG
GTGGTATCGGTGGCGCTGGCTGTGCTGTTGTGGGTGATCTACATCCTGGAGGGCTCGGCTGATGCATTGACTGATTTAGC
GAGTGCCAGGGTAGTGCACAACTTGCGCCTTGAGCTTTCGGGCAAGTTGGTTACTACGCCACGTAATTCGCTGACTCCTG
GTGAGATGTTGAATACGGTCGATCAGGACTCGGTTCAAATTGGTGGGTTGAAGCAGGTGCTGAACTTTCCCATCATGATG
GTGGGCTATTTGTTGGGTTCCACTATTTCTATTGCGCCGATTTCTCCGCTGATTGCGGTGTTACTCGTGGTGGGTGGAGT
GTTTACCGCGTTGGCTTCCTATTTCACGGCAACTCCGTTGACTAAGATTTCCGCGAAACGCCGTGAGGCGGAATCGAAGT
CGGTGTCTTTGGCTACCGATGTGGCGCAGGGATCCAGGGTGGTGAAAGGTTTGGGCGCTGTTTCTCAAACTGAGGAGCGC
TTTGGCGCAGCGGCTGATGAAGCCTTGGCAATCATGTTGAAGGAAGTTCGTCTGCAGTCGTTGCTGACTTTTGTGCGCCA
ACTTGTCCCAGCGGTGTTTTCTGTGGGTCTTTTGGCTTATGCGTCACTGTTGGCTTTTGACGGTGACATAACTGGTGGTG
AGATGATCTCGGTGACGTTGCTGGTGCCACCTTCGTTGACTGTGTTGGGTGTGTCGCTTGGCATGATGACAGAGATTTGG
GCTAGGGGACAGGCTTCGACAAAAAGGGTCCAAAACTTAGTCACTGAACTGGATAAGGCGGCCGCTGAGCCACGACCTCA
GCCTGCCACCTTTGAATTTGAAGAGGGGATCACGGTGTGGGATCCTTCGACACCTGAGGCACGCGATGTGATTGATCGGG
AGTTGGAGGCGCTTCAGGTTCGTGAAGATGTCATTGTGGCTCCTCACCGCGTCAGCGTGTTTGAAGGTGTGCTGAAGGAT
AATTTGAATCCGATGGGCACTATCGCACCGGAGATGCTGCGCGCTGCTCTTCATGCTGCAAGTTGTGAGGACATCTTGAG
CCGATTGGGTGCTGATCTGAACATGCCGGGGGAGTTTGAGCTTCCAGATACCTTGATCGGCGAGGCCGGATTGAATCTCT
CCGGTGGCCAACGCCAGAGGATTGCTTTGGCACGATTCTTGGCTGTTGATCCTGAGGTGCTCATTTTGGATGAACCGACC
ACGGGGTTGGATGCGGTGACCCTGGATGAAGTGGCACATCGCGTCGAAAAGCTTCGTCGAGGCCGGAAAACCGTCGTCAT
TACGTCGAACCCGACGTGGCACGGCGTCGCAAAGCAGATGCAATCTGATTTTTCGGAAGGGGTGAAGTAG

Upstream 100 bases:

>100_bases
GGTCATTAGCTAAAAAGACAAAGTTGTACTTACAGCTTTGTAAGTACTGTCCGTATAAAGCTGCGGTAGTGTTTTCGCCA
TGACAAATGAATTCCCCAGG

Downstream 100 bases:

>100_bases
ATGGCGCAGCATGAGCGCGTTGCGGATGCGCTGCAGCCGGCGTCGTTGGCGGAGTCGTGGCGTGAGCTGAAAACGATGCC
TTCGGGGCCCAAGGCCTGGT

Product: ABC-type multidrug/protein/lipid transport system, ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MRTWSWFVPDSPDEGTPLLPKLENSTPVKSAWALLWAFPAATWLLVFGMLVSSMFGAVVSLVVGRGSEWAFGSGELMPVL
VVSVALAVLLWVIYILEGSADALTDLASARVVHNLRLELSGKLVTTPRNSLTPGEMLNTVDQDSVQIGGLKQVLNFPIMM
VGYLLGSTISIAPISPLIAVLLVVGGVFTALASYFTATPLTKISAKRREAESKSVSLATDVAQGSRVVKGLGAVSQTEER
FGAAADEALAIMLKEVRLQSLLTFVRQLVPAVFSVGLLAYASLLAFDGDITGGEMISVTLLVPPSLTVLGVSLGMMTEIW
ARGQASTKRVQNLVTELDKAAAEPRPQPATFEFEEGITVWDPSTPEARDVIDRELEALQVREDVIVAPHRVSVFEGVLKD
NLNPMGTIAPEMLRAALHAASCEDILSRLGADLNMPGEFELPDTLIGEAGLNLSGGQRQRIALARFLAVDPEVLILDEPT
TGLDAVTLDEVAHRVEKLRRGRKTVVITSNPTWHGVAKQMQSDFSEGVK

Sequences:

>Translated_529_residues
MRTWSWFVPDSPDEGTPLLPKLENSTPVKSAWALLWAFPAATWLLVFGMLVSSMFGAVVSLVVGRGSEWAFGSGELMPVL
VVSVALAVLLWVIYILEGSADALTDLASARVVHNLRLELSGKLVTTPRNSLTPGEMLNTVDQDSVQIGGLKQVLNFPIMM
VGYLLGSTISIAPISPLIAVLLVVGGVFTALASYFTATPLTKISAKRREAESKSVSLATDVAQGSRVVKGLGAVSQTEER
FGAAADEALAIMLKEVRLQSLLTFVRQLVPAVFSVGLLAYASLLAFDGDITGGEMISVTLLVPPSLTVLGVSLGMMTEIW
ARGQASTKRVQNLVTELDKAAAEPRPQPATFEFEEGITVWDPSTPEARDVIDRELEALQVREDVIVAPHRVSVFEGVLKD
NLNPMGTIAPEMLRAALHAASCEDILSRLGADLNMPGEFELPDTLIGEAGLNLSGGQRQRIALARFLAVDPEVLILDEPT
TGLDAVTLDEVAHRVEKLRRGRKTVVITSNPTWHGVAKQMQSDFSEGVK
>Mature_529_residues
MRTWSWFVPDSPDEGTPLLPKLENSTPVKSAWALLWAFPAATWLLVFGMLVSSMFGAVVSLVVGRGSEWAFGSGELMPVL
VVSVALAVLLWVIYILEGSADALTDLASARVVHNLRLELSGKLVTTPRNSLTPGEMLNTVDQDSVQIGGLKQVLNFPIMM
VGYLLGSTISIAPISPLIAVLLVVGGVFTALASYFTATPLTKISAKRREAESKSVSLATDVAQGSRVVKGLGAVSQTEER
FGAAADEALAIMLKEVRLQSLLTFVRQLVPAVFSVGLLAYASLLAFDGDITGGEMISVTLLVPPSLTVLGVSLGMMTEIW
ARGQASTKRVQNLVTELDKAAAEPRPQPATFEFEEGITVWDPSTPEARDVIDRELEALQVREDVIVAPHRVSVFEGVLKD
NLNPMGTIAPEMLRAALHAASCEDILSRLGADLNMPGEFELPDTLIGEAGLNLSGGQRQRIALARFLAVDPEVLILDEPT
TGLDAVTLDEVAHRVEKLRRGRKTVVITSNPTWHGVAKQMQSDFSEGVK

Specific function: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI4505771, Length=154, Percent_Identity=32.4675324675325, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI9961252, Length=154, Percent_Identity=32.4675324675325, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI9961250, Length=154, Percent_Identity=32.4675324675325, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI42741659, Length=489, Percent_Identity=24.5398773006135, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI255708477, Length=137, Percent_Identity=34.3065693430657, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI148612844, Length=137, Percent_Identity=34.3065693430657, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787143, Length=487, Percent_Identity=22.5872689938398, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787112, Length=156, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=146, Percent_Identity=36.3013698630137, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=157, Percent_Identity=31.8471337579618, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17567269, Length=151, Percent_Identity=36.4238410596026, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567265, Length=136, Percent_Identity=32.3529411764706, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=129, Percent_Identity=34.1085271317829, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=142, Percent_Identity=36.6197183098592, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=138, Percent_Identity=31.1594202898551, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=133, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=136, Percent_Identity=30.1470588235294, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=136, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=122, Percent_Identity=37.7049180327869, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324985, Length=154, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI23397593, Length=542, Percent_Identity=23.2472324723247, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI85726357, Length=65, Percent_Identity=52.3076923076923, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24653245, Length=151, Percent_Identity=35.7615894039735, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641565, Length=108, Percent_Identity=42.5925925925926, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI281363262, Length=151, Percent_Identity=35.7615894039735, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17136662, Length=142, Percent_Identity=31.6901408450704, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011917
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56796; Mature: 56796

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTWSWFVPDSPDEGTPLLPKLENSTPVKSAWALLWAFPAATWLLVFGMLVSSMFGAVVS
CCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVGRGSEWAFGSGELMPVLVVSVALAVLLWVIYILEGSADALTDLASARVVHNLRLELS
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEC
GKLVTTPRNSLTPGEMLNTVDQDSVQIGGLKQVLNFPIMMVGYLLGSTISIAPISPLIAV
CEEEECCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LLVVGGVFTALASYFTATPLTKISAKRREAESKSVSLATDVAQGSRVVKGLGAVSQTEER
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAAADEALAIMLKEVRLQSLLTFVRQLVPAVFSVGLLAYASLLAFDGDITGGEMISVTL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
LVPPSLTVLGVSLGMMTEIWARGQASTKRVQNLVTELDKAAAEPRPQPATFEFEEGITVW
EECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEE
DPSTPEARDVIDRELEALQVREDVIVAPHRVSVFEGVLKDNLNPMGTIAPEMLRAALHAA
CCCCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
SCEDILSRLGADLNMPGEFELPDTLIGEAGLNLSGGQRQRIALARFLAVDPEVLILDEPT
CHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
TGLDAVTLDEVAHRVEKLRRGRKTVVITSNPTWHGVAKQMQSDFSEGVK
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTWSWFVPDSPDEGTPLLPKLENSTPVKSAWALLWAFPAATWLLVFGMLVSSMFGAVVS
CCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVGRGSEWAFGSGELMPVLVVSVALAVLLWVIYILEGSADALTDLASARVVHNLRLELS
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEC
GKLVTTPRNSLTPGEMLNTVDQDSVQIGGLKQVLNFPIMMVGYLLGSTISIAPISPLIAV
CEEEECCCCCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LLVVGGVFTALASYFTATPLTKISAKRREAESKSVSLATDVAQGSRVVKGLGAVSQTEER
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAAADEALAIMLKEVRLQSLLTFVRQLVPAVFSVGLLAYASLLAFDGDITGGEMISVTL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
LVPPSLTVLGVSLGMMTEIWARGQASTKRVQNLVTELDKAAAEPRPQPATFEFEEGITVW
EECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEE
DPSTPEARDVIDRELEALQVREDVIVAPHRVSVFEGVLKDNLNPMGTIAPEMLRAALHAA
CCCCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
SCEDILSRLGADLNMPGEFELPDTLIGEAGLNLSGGQRQRIALARFLAVDPEVLILDEPT
CHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
TGLDAVTLDEVAHRVEKLRRGRKTVVITSNPTWHGVAKQMQSDFSEGVK
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA