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The map label for this gene is irtA [H]

Identifier: 62390334

GI number: 62390334

Start: 1530953

End: 1531690

Strand: Direct

Name: irtA [H]

Synonym: cg1642

Alternate gene names: 62390334

Gene position: 1530953-1531690 (Clockwise)

Preceding gene: 62390327

Following gene: 62390336

Centisome position: 46.64

GC content: 56.91

Gene sequence:

>738_bases
ATGGGCAAGGGATTTACCGGCGCTATTTTGACCGTCATGGGCGTGAAATCGCATATCGCCACCACCACGGGAAAAACCGT
GATCAATGACCGCATGGTGACCATTCATTTTCATTCCGAGACGCTGCTCAACACGGAAGGTGAAGTCCCCGGCGATTGGC
TGCGTCTGTGGTTCCCGCACGAGAGCCGACCTGGAAAGCTCTACCAACGCGCCTACACCTTGACCAACGTGGATGCCGAT
GCCGGTACCTTTGACCTGGCTTTTGTGCTGCACGAGCCGCTGGGGCCCGCCTCGGCGTGGGCGACGCGCTGCGAGGCCGG
GGAAAGCCTGGAAGTCATGCGCTACCCAGGAATTCCGTTCGCCATCCCAGATCCAGCGCCGCGTGGCTTCCTTTTCTTAG
GCGATCTCACCTCTTACCCAGCGATCTGCTCGATTCTGGAGACCTTGGACGGTGAAATCCCTGCGACCGCGTATCTTATC
GCCCACGATCCACTTGATTACACCTTCGATTTTCCCCAGGGCGAGCACATCACCGCGCAGTGGATTTCCAACGAACAATC
CTTCATTGATCACATCGCTGACACGGATTACACCGATTTTTATACCTGGATCGGCGCGGAATCCTCCGAAACCCGTGCGG
CCAAGAAGCATCTGCAGACCCACGCCGGCATGCCCAAGACGCACATGAACGCGCAAGGTTATTGGAACAAGGGCAGAGCC
ATGGGTAAAAGCAATTAA

Upstream 100 bases:

>100_bases
GCTGAGCTAGTGCTTTTGCGACACACCTCTTGCGAATGTTGATTAGGTTAGGCAAGCCATATTTACAGGGTGTTGTGAAA
GCATAAGGGAGCAAGGAAAC

Downstream 100 bases:

>100_bases
AAGATTTTTGCTTATCGACGCCCACCTCCGGCGAATCCCTGGCAGCACGCGAAAAACCCCTCACAATCTAAGGTGACTGT
GAGGGGTTTTGGCGTTGTGT

Product: siderophore-interacting protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MGKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWLRLWFPHESRPGKLYQRAYTLTNVDAD
AGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPFAIPDPAPRGFLFLGDLTSYPAICSILETLDGEIPATAYLI
AHDPLDYTFDFPQGEHITAQWISNEQSFIDHIADTDYTDFYTWIGAESSETRAAKKHLQTHAGMPKTHMNAQGYWNKGRA
MGKSN

Sequences:

>Translated_245_residues
MGKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWLRLWFPHESRPGKLYQRAYTLTNVDAD
AGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPFAIPDPAPRGFLFLGDLTSYPAICSILETLDGEIPATAYLI
AHDPLDYTFDFPQGEHITAQWISNEQSFIDHIADTDYTDFYTWIGAESSETRAAKKHLQTHAGMPKTHMNAQGYWNKGRA
MGKSN
>Mature_244_residues
GKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWLRLWFPHESRPGKLYQRAYTLTNVDADA
GTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPFAIPDPAPRGFLFLGDLTSYPAICSILETLDGEIPATAYLIA
HDPLDYTFDFPQGEHITAQWISNEQSFIDHIADTDYTDFYTWIGAESSETRAAKKHLQTHAGMPKTHMNAQGYWNKGRAM
GKSN

Specific function: Part of the ABC transporter complex IrtAB involved in iron import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG2375

COG function: function code P; Siderophore-interacting protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR013113
- InterPro:   IPR017927
- InterPro:   IPR017938
- InterPro:   IPR007037 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran; PF08021 FAD_binding_9; PF04954 SIP [H]

EC number: NA

Molecular weight: Translated: 27137; Mature: 27006

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWLRLWFPH
CCCCCCHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCEEECCCCCCCCCEEEEEECC
ESRPGKLYQRAYTLTNVDADAGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPF
CCCCCHHHHHEEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCE
AIPDPAPRGFLFLGDLTSYPAICSILETLDGEIPATAYLIAHDPLDYTFDFPQGEHITAQ
ECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCCEEEEE
WISNEQSFIDHIADTDYTDFYTWIGAESSETRAAKKHLQTHAGMPKTHMNAQGYWNKGRA
ECCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
MGKSN
CCCCC
>Mature Secondary Structure 
GKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWLRLWFPH
CCCCCHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCEEECCCCCCCCCEEEEEECC
ESRPGKLYQRAYTLTNVDADAGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPF
CCCCCHHHHHEEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCE
AIPDPAPRGFLFLGDLTSYPAICSILETLDGEIPATAYLIAHDPLDYTFDFPQGEHITAQ
ECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCCEEEEE
WISNEQSFIDHIADTDYTDFYTWIGAESSETRAAKKHLQTHAGMPKTHMNAQGYWNKGRA
ECCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
MGKSN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]