Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 62390263

GI number: 62390263

Start: 1449259

End: 1449828

Strand: Direct

Name: infC [H]

Synonym: cg1563

Alternate gene names: 62390263

Gene position: 1449259-1449828 (Clockwise)

Preceding gene: 62390261

Following gene: 62390264

Centisome position: 44.15

GC content: 53.16

Gene sequence:

>570_bases
GTGGTTCGGTACGTCAAATTTTCCCGCACTGCTAACAGAGGAGTCCACATCAGCGCTGAAGCTCGCATTAATGAGCGCAT
CCGAGTTCCCGAAGTCCGCCTTGTCGGACCTAACGGTGAGCAAGTAGGCATCGTCCGTATCGAAGATGCCCGCAAGCTCG
CATTCGACGCAGACCTAGACCTGGTCGAGGTCGCACCCAACGCCAAACCTCCAGTCTGCAAGATCATGGACTACGGAAAG
TTCAAGTACGAAGCGGCCCAAAAGGCTCGTGAGTCACGCAAGAATCAGCAGCAGACCGTGGTCAAAGAGCAAAAGCTTCG
TCCCAAGATCGATGATCATGATTATGAGACGAAGAAGAACAATGTGATCCGATTCCTTGAAAAGGGATCAAAGGTCAAAG
TCACGATCATGTTCCGTGGTCGTGAGCAGGCTCGCCCAGAGCTTGGCTACAGGCTCCTCGAGCGACTGGCAAACGATGTC
GTAGATTTTGGCATCGTGGAAACCCGCGCAAAGCAGGACGGACGAAACATGACAATGGTTCTCGGTCCGGTGCGCAAGGG
CAAGAAATAA

Upstream 100 bases:

>100_bases
GACACGGACTAGTGCCCGTGTATAACTCTTGAAAGTCAGATCTCCCGTTCATCCTAGATGATGAACGGGTTTTTGGTCTG
CATAGGGGCAATCACCTCAA

Downstream 100 bases:

>100_bases
TCACGAATAGGGTTTAAGGACAACTTTCATGAAGAACAAGACCCACAAGGGCACCGCAAAGCGCGTTAAGGTGACTGGCT
CCGGCAAGCTCGTTCGCGAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVRYVKFSRTANRGVHISAEARINERIRVPEVRLVGPNGEQVGIVRIEDARKLAFDADLDLVEVAPNAKPPVCKIMDYGK
FKYEAAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGREQARPELGYRLLERLANDV
VDFGIVETRAKQDGRNMTMVLGPVRKGKK

Sequences:

>Translated_189_residues
MVRYVKFSRTANRGVHISAEARINERIRVPEVRLVGPNGEQVGIVRIEDARKLAFDADLDLVEVAPNAKPPVCKIMDYGK
FKYEAAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGREQARPELGYRLLERLANDV
VDFGIVETRAKQDGRNMTMVLGPVRKGKK
>Mature_189_residues
MVRYVKFSRTANRGVHISAEARINERIRVPEVRLVGPNGEQVGIVRIEDARKLAFDADLDLVEVAPNAKPPVCKIMDYGK
FKYEAAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGREQARPELGYRLLERLANDV
VDFGIVETRAKQDGRNMTMVLGPVRKGKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=49.3975903614458, Blast_Score=150, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21719; Mature: 21719

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRYVKFSRTANRGVHISAEARINERIRVPEVRLVGPNGEQVGIVRIEDARKLAFDADLD
CCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEEECCCCEEEECCCCC
LVEVAPNAKPPVCKIMDYGKFKYEAAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKN
EEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
NVIRFLEKGSKVKVTIMFRGREQARPELGYRLLERLANDVVDFGIVETRAKQDGRNMTMV
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEEE
LGPVRKGKK
EECCCCCCC
>Mature Secondary Structure
MVRYVKFSRTANRGVHISAEARINERIRVPEVRLVGPNGEQVGIVRIEDARKLAFDADLD
CCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEEECCCCEEEECCCCC
LVEVAPNAKPPVCKIMDYGKFKYEAAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKN
EEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
NVIRFLEKGSKVKVTIMFRGREQARPELGYRLLERLANDVVDFGIVETRAKQDGRNMTMV
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEEE
LGPVRKGKK
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]