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The map label for this gene is ung

Identifier: 62390206

GI number: 62390206

Start: 1389794

End: 1390543

Strand: Direct

Name: ung

Synonym: cg1496

Alternate gene names: 62390206

Gene position: 1389794-1390543 (Clockwise)

Preceding gene: 62390205

Following gene: 62390207

Centisome position: 42.34

GC content: 54.67

Gene sequence:

>750_bases
ATGACCAACACCCTATGGAATTCAGTAGACGAACTCCCCATCCACGACTCCTGGAAACCAGTACTCAAACCAGTCGAAGA
CGCCATCCGAAAACTCGGTGTATTCCTCGCGGAAGAAGAATTCCTTCCACCAGTAGATGACGTATTCAGAGCATTTAGCT
ACCCCTTTGACGCAGTAAAAGTACTGATCATGGGACAAGACCCATATCCCACCCCAGGACATGCCATGGGACTGAGCTTT
TCCACCCAACCAGACGTACGACCACTGCCACGGAGCCTGAACAATATCTTCAAAGAGCTGGTGAGTGATGTCGGCTCTTT
AGGCGATTCGGCGTCAGAGCAGGGGGCCTTGGACTTAGGTATTAACGCGCCGGGCTCTGTCGCTGGCACACAAGTTGCCT
TGCCCGCGGACGGCGACCTCCGTGCATGGAGCAACCAAGGCGTCGCATTGTTCAACCGCGTACTCACCGTCCACCCAGGC
CAGGCCGGAAGCCACAAGGGTAAAGGCTGGGAAGCGGTAACCGAACAGGCGATTAAAGCCTTGGCGGAGCGGGATCAACC
CTTGGTGGCAATCCTGTGGGGTAAACAAGCCCAAGAGGTACAGAAATTCCTTGGAGATACGCCGTGTATCTGCTCAGTGC
ACCCATCACCGCTGTCGGCGTCGAGAGGCTTTTTTGGCTCTAAGCCTTTTAGTCGTGCGAACGAAATCTTAAGCAGCCTC
GGTGCCACCGAGATCGATTGGTCGCTGTAA

Upstream 100 bases:

>100_bases
GATTCCGCACCATCGGCCAAGTCACCAAAACACGCCACGAAGACCTCGTCACCGTAGATAAGAAAACCCCCGCATTTTCC
GATGGATGGAGAAGCTTCTA

Downstream 100 bases:

>100_bases
GGTATCTGATTATGTCCAGTTCCGAAAGCTCGCGTTCCGAAGGCTCGCAGCCAGCACCGTCTGTACAGCCTGAACGCCGT
GCTGATTCAACGGGGGCTCC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTNTLWNSVDELPIHDSWKPVLKPVEDAIRKLGVFLAEEEFLPPVDDVFRAFSYPFDAVKVLIMGQDPYPTPGHAMGLSF
STQPDVRPLPRSLNNIFKELVSDVGSLGDSASEQGALDLGINAPGSVAGTQVALPADGDLRAWSNQGVALFNRVLTVHPG
QAGSHKGKGWEAVTEQAIKALAERDQPLVAILWGKQAQEVQKFLGDTPCICSVHPSPLSASRGFFGSKPFSRANEILSSL
GATEIDWSL

Sequences:

>Translated_249_residues
MTNTLWNSVDELPIHDSWKPVLKPVEDAIRKLGVFLAEEEFLPPVDDVFRAFSYPFDAVKVLIMGQDPYPTPGHAMGLSF
STQPDVRPLPRSLNNIFKELVSDVGSLGDSASEQGALDLGINAPGSVAGTQVALPADGDLRAWSNQGVALFNRVLTVHPG
QAGSHKGKGWEAVTEQAIKALAERDQPLVAILWGKQAQEVQKFLGDTPCICSVHPSPLSASRGFFGSKPFSRANEILSSL
GATEIDWSL
>Mature_248_residues
TNTLWNSVDELPIHDSWKPVLKPVEDAIRKLGVFLAEEEFLPPVDDVFRAFSYPFDAVKVLIMGQDPYPTPGHAMGLSFS
TQPDVRPLPRSLNNIFKELVSDVGSLGDSASEQGALDLGINAPGSVAGTQVALPADGDLRAWSNQGVALFNRVLTVHPGQ
AGSHKGKGWEAVTEQAIKALAERDQPLVAILWGKQAQEVQKFLGDTPCICSVHPSPLSASRGFFGSKPFSRANEILSSLG
ATEIDWSL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family

Homologues:

Organism=Homo sapiens, GI6224979, Length=225, Percent_Identity=39.1111111111111, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI19718751, Length=224, Percent_Identity=39.2857142857143, Blast_Score=133, Evalue=1e-31,
Organism=Escherichia coli, GI1788934, Length=208, Percent_Identity=39.9038461538462, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17556304, Length=245, Percent_Identity=34.6938775510204, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323620, Length=263, Percent_Identity=36.5019011406844, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UNG_CORGL (Q8NQU9)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927151
- RefSeq:   NP_600544.1
- RefSeq:   YP_225608.1
- ProteinModelPortal:   Q8NQU9
- SMR:   Q8NQU9
- GeneID:   1019300
- GeneID:   3345485
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg1496
- KEGG:   cgl:NCgl1270
- HOGENOM:   HBG605450
- OMA:   VMLLNRV
- ProtClustDB:   PRK05254
- BioCyc:   CGLU196627:CG1496-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00148
- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122
- Gene3D:   G3DSA:3.40.470.10
- PANTHER:   PTHR11264

Pfam domain/function: PF03167 UDG; SSF52141 UDNA_glycsylseSF

EC number: =3.2.2.27

Molecular weight: Translated: 26829; Mature: 26697

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: ACT_SITE 72-72

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLWNSVDELPIHDSWKPVLKPVEDAIRKLGVFLAEEEFLPPVDDVFRAFSYPFDAVK
CCCCHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHEE
VLIMGQDPYPTPGHAMGLSFSTQPDVRPLPRSLNNIFKELVSDVGSLGDSASEQGALDLG
EEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
INAPGSVAGTQVALPADGDLRAWSNQGVALFNRVLTVHPGQAGSHKGKGWEAVTEQAIKA
CCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LAERDQPLVAILWGKQAQEVQKFLGDTPCICSVHPSPLSASRGFFGSKPFSRANEILSSL
HHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHC
GATEIDWSL
CCCCCCCCC
>Mature Secondary Structure 
TNTLWNSVDELPIHDSWKPVLKPVEDAIRKLGVFLAEEEFLPPVDDVFRAFSYPFDAVK
CCCHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHEE
VLIMGQDPYPTPGHAMGLSFSTQPDVRPLPRSLNNIFKELVSDVGSLGDSASEQGALDLG
EEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
INAPGSVAGTQVALPADGDLRAWSNQGVALFNRVLTVHPGQAGSHKGKGWEAVTEQAIKA
CCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LAERDQPLVAILWGKQAQEVQKFLGDTPCICSVHPSPLSASRGFFGSKPFSRANEILSSL
HHHCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHC
GATEIDWSL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626