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The map label for this gene is fno [H]

Identifier: 62390147

GI number: 62390147

Start: 1327943

End: 1328521

Strand: Direct

Name: fno [H]

Synonym: cg1421

Alternate gene names: 62390147

Gene position: 1327943-1328521 (Clockwise)

Preceding gene: 62390146

Following gene: 62390148

Centisome position: 40.45

GC content: 54.23

Gene sequence:

>579_bases
ATGACCACTTACACCATCTTCGGCCGCGGCAACATGGGCACCGCAATCGCAGGCGTCCTCACCAAGGGTGGTGCAACTGT
AGAACACATCGGTTCTGCAGATTCTGACATCGCAACCATCAACGGTGACGTTGTTATCCTTGCTGTTCCTTACCCAGCAG
TAGAGTCCATCATTGCAAGCCACAAGGATGCTCTCGCAGGCAAGACCGTTATCGATATCACCAACCCACTTAACTTCGAG
ACCTTCGATTCCCTCGTCGTTCCAGTTGGTTCTTCTGCAACCGCTGAGATCCAGGCTCAGCTTCCAACCTCCCGCGTTTT
GAAGGCTTTCAACACCAACTTCGCAGCCACTTTGGCTACCGGAAAGGTTGGCGATATCACCACCACCGTTTTAGTTGCAG
GCGATGATGAAGACGCAAAGAACGCTCTTATCACCGACGTCAACGCTGGCGGCCTCGACGCCCTTGACGCTGGTTCCCTC
AAGCGTGCACACGAGCTTGAAGCAGTTGGTTTCCTGCAGCTCACCCTTGCAGGTTCCGAGAAGATTGGATGGACCGGCGG
ATTCGGCCTGGTCAAGTAA

Upstream 100 bases:

>100_bases
GTTCATGATCAAAGAACTGCTCAACAAGCTCTTCGGAAACAAGAAGGCTTCCCCGGCAATGACACAATCTGAAACCATTT
CACACAAGGAGAACAACACA

Downstream 100 bases:

>100_bases
CACCCAGCCTCAAAAGCACTGATAAAAGCAGTCAACCCACCTCGGGTTGGCTGCTTTTTTGCATCCAGATGCACAAAGCC
GTGGCACAAACGAGACAAAC

Product: dinucleotide-binding enzyme

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTTYTIFGRGNMGTAIAGVLTKGGATVEHIGSADSDIATINGDVVILAVPYPAVESIIASHKDALAGKTVIDITNPLNFE
TFDSLVVPVGSSATAEIQAQLPTSRVLKAFNTNFAATLATGKVGDITTTVLVAGDDEDAKNALITDVNAGGLDALDAGSL
KRAHELEAVGFLQLTLAGSEKIGWTGGFGLVK

Sequences:

>Translated_192_residues
MTTYTIFGRGNMGTAIAGVLTKGGATVEHIGSADSDIATINGDVVILAVPYPAVESIIASHKDALAGKTVIDITNPLNFE
TFDSLVVPVGSSATAEIQAQLPTSRVLKAFNTNFAATLATGKVGDITTTVLVAGDDEDAKNALITDVNAGGLDALDAGSL
KRAHELEAVGFLQLTLAGSEKIGWTGGFGLVK
>Mature_191_residues
TTYTIFGRGNMGTAIAGVLTKGGATVEHIGSADSDIATINGDVVILAVPYPAVESIIASHKDALAGKTVIDITNPLNFET
FDSLVVPVGSSATAEIQAQLPTSRVLKAFNTNFAATLATGKVGDITTTVLVAGDDEDAKNALITDVNAGGLDALDAGSLK
RAHELEAVGFLQLTLAGSEKIGWTGGFGLVK

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 19572; Mature: 19441

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYTIFGRGNMGTAIAGVLTKGGATVEHIGSADSDIATINGDVVILAVPYPAVESIIAS
CCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCEEEECCCEEEEEECCHHHHHHHHH
HKDALAGKTVIDITNPLNFETFDSLVVPVGSSATAEIQAQLPTSRVLKAFNTNFAATLAT
HHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHCCCEEEEEEC
GKVGDITTTVLVAGDDEDAKNALITDVNAGGLDALDAGSLKRAHELEAVGFLQLTLAGSE
CCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCEEEEEEEEEECCC
KIGWTGGFGLVK
CCCEECCCCCCC
>Mature Secondary Structure 
TTYTIFGRGNMGTAIAGVLTKGGATVEHIGSADSDIATINGDVVILAVPYPAVESIIAS
CEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCEEEECCCEEEEEECCHHHHHHHHH
HKDALAGKTVIDITNPLNFETFDSLVVPVGSSATAEIQAQLPTSRVLKAFNTNFAATLAT
HHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHCCCEEEEEEC
GKVGDITTTVLVAGDDEDAKNALITDVNAGGLDALDAGSLKRAHELEAVGFLQLTLAGSE
CCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCEEEEEEEEEECCC
KIGWTGGFGLVK
CCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]