Click here to switch to the map view.

The map label for this gene is atpB [H]

Identifier: 62390094

GI number: 62390094

Start: 1273652

End: 1274620

Strand: Direct

Name: atpB [H]

Synonym: cg1362

Alternate gene names: 62390094

Gene position: 1273652-1274620 (Clockwise)

Preceding gene: 62390093

Following gene: 62390095

Centisome position: 38.8

GC content: 50.67

Gene sequence:

>969_bases
TTGCGGAGCACGTCCCCTGTGATCGTTGCGCTGATGTGCGACGGAGTCCGTAGCGATTACAGCGAGTTTTTCAGACGTCC
ATCGCACCGTGCACAACAACATTTCAGGTGCACGGCCCGAACACGGGAGAGAACGCTGAGCGTTACAACACTGTCCATGA
AGGGCGAATTCCACGCCCCCGATTTGGACAAAGAATTTTTCCCGGGGCACGTAACCGATAGTGGTGAAGTCGTGAACATG
CTGTTCACCGATTTCGCTAATGGTTGGTTCGCAATGGACCGCATCGTATTGATCCGTCTTCTTATGACGGCAGTCGTTGT
GGTCTTCTTCCTTTGGGCTATGCGCAAGCCAAAGCTTGTTCCGCATGGCGTCCAGAATTTTGCAGAGTACGCACTCGATT
TCGTTCGTATTCACATCGCTGAAGACATCCTCGGAAAGAAGGAAGGTCGTCGGTTCCTGCCGATCCTGGCCACCATCTTC
TTCGCGGCTCTGTTGATGAACCTTGCAACGATCATCCCGGGACTAAACATCTCCTCCAACTCACGTATTGCATTCCCAAT
CGTGATGGCGGTAGCTGGTTACATCGCGTTTATCTACGCAGGCTCTAAGCGTTACGGATTCTTCAAATATGTGAAGTCTT
CTGTTGTGATTCCGAACATTCCACCAGCACTTCACGTCTTGGTGGTTCCAATTGAGTTCTTCTCTACATTCATCTTGAGG
CCAGTCACCCTGGCACTGCGTTTGATGGCCAACTTCCTTGCTGGCCACATCATCCTGGTTCTGCTTTTCTCCGCAACGAA
CTTCTTCTTCTTCCAGTTCAACGGATGGACAGCAATGTCCGGCGTAACCATCTTGATGGCAGTACTCTTCACGGTTTACG
AGATCATTGTTATCTTCCTGCAGGCATACATCTTCGCTCTGCTGGTCGCTGTATACATTGAGCTTTCACTTCACGCGGAT
TCTCACTAG

Upstream 100 bases:

>100_bases
CCCCGCCCCACTTGGATAAAAGACGAATTCACCTGTTAGTCTATAACGCGGGTTGAACCGAGAAACCCCTCAAGGCAGCA
GACAATAGCCGCAAGGGGTT

Downstream 100 bases:

>100_bases
ATGAAAAAGGTCGCTATTAAAAGCTTCTTGCACAAGTCGCCCAGATAGCGAGCGGACCACTCGGTCAACTGAATAACCCC
ACTAAACACTTCACAGCCCG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRSTSPVIVALMCDGVRSDYSEFFRRPSHRAQQHFRCTARTRERTLSVTTLSMKGEFHAPDLDKEFFPGHVTDSGEVVNM
LFTDFANGWFAMDRIVLIRLLMTAVVVVFFLWAMRKPKLVPHGVQNFAEYALDFVRIHIAEDILGKKEGRRFLPILATIF
FAALLMNLATIIPGLNISSNSRIAFPIVMAVAGYIAFIYAGSKRYGFFKYVKSSVVIPNIPPALHVLVVPIEFFSTFILR
PVTLALRLMANFLAGHIILVLLFSATNFFFFQFNGWTAMSGVTILMAVLFTVYEIIVIFLQAYIFALLVAVYIELSLHAD
SH

Sequences:

>Translated_322_residues
MRSTSPVIVALMCDGVRSDYSEFFRRPSHRAQQHFRCTARTRERTLSVTTLSMKGEFHAPDLDKEFFPGHVTDSGEVVNM
LFTDFANGWFAMDRIVLIRLLMTAVVVVFFLWAMRKPKLVPHGVQNFAEYALDFVRIHIAEDILGKKEGRRFLPILATIF
FAALLMNLATIIPGLNISSNSRIAFPIVMAVAGYIAFIYAGSKRYGFFKYVKSSVVIPNIPPALHVLVVPIEFFSTFILR
PVTLALRLMANFLAGHIILVLLFSATNFFFFQFNGWTAMSGVTILMAVLFTVYEIIVIFLQAYIFALLVAVYIELSLHAD
SH
>Mature_322_residues
MRSTSPVIVALMCDGVRSDYSEFFRRPSHRAQQHFRCTARTRERTLSVTTLSMKGEFHAPDLDKEFFPGHVTDSGEVVNM
LFTDFANGWFAMDRIVLIRLLMTAVVVVFFLWAMRKPKLVPHGVQNFAEYALDFVRIHIAEDILGKKEGRRFLPILATIF
FAALLMNLATIIPGLNISSNSRIAFPIVMAVAGYIAFIYAGSKRYGFFKYVKSSVVIPNIPPALHVLVVPIEFFSTFILR
PVTLALRLMANFLAGHIILVLLFSATNFFFFQFNGWTAMSGVTILMAVLFTVYEIIVIFLQAYIFALLVAVYIELSLHAD
SH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 36410; Mature: 36410

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTSPVIVALMCDGVRSDYSEFFRRPSHRAQQHFRCTARTRERTLSVTTLSMKGEFHAP
CCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCC
DLDKEFFPGHVTDSGEVVNMLFTDFANGWFAMDRIVLIRLLMTAVVVVFFLWAMRKPKLV
CCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHGVQNFAEYALDFVRIHIAEDILGKKEGRRFLPILATIFFAALLMNLATIIPGLNISSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SRIAFPIVMAVAGYIAFIYAGSKRYGFFKYVKSSVVIPNIPPALHVLVVPIEFFSTFILR
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PVTLALRLMANFLAGHIILVLLFSATNFFFFQFNGWTAMSGVTILMAVLFTVYEIIVIFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QAYIFALLVAVYIELSLHADSH
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSTSPVIVALMCDGVRSDYSEFFRRPSHRAQQHFRCTARTRERTLSVTTLSMKGEFHAP
CCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCC
DLDKEFFPGHVTDSGEVVNMLFTDFANGWFAMDRIVLIRLLMTAVVVVFFLWAMRKPKLV
CCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHGVQNFAEYALDFVRIHIAEDILGKKEGRRFLPILATIFFAALLMNLATIIPGLNISSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SRIAFPIVMAVAGYIAFIYAGSKRYGFFKYVKSSVVIPNIPPALHVLVVPIEFFSTFILR
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PVTLALRLMANFLAGHIILVLLFSATNFFFFQFNGWTAMSGVTILMAVLFTVYEIIVIFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QAYIFALLVAVYIELSLHADSH
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA