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The map label for this gene is typA [H]

Identifier: 62389988

GI number: 62389988

Start: 1145577

End: 1147499

Strand: Direct

Name: typA [H]

Synonym: cg1248

Alternate gene names: 62389988

Gene position: 1145577-1147499 (Clockwise)

Preceding gene: 62389985

Following gene: 62389989

Centisome position: 34.9

GC content: 56.32

Gene sequence:

>1923_bases
ATGCCCCCAGTGACCCACCCAGAGTTTCGTAACGTAGCGATTGTCGCGCACGTTGACCACGGAAAGACCACACTCGTTAA
TGCCATGCTTGAACAGTCTGGCGTATTCAGTGACCACGGTGAAGTAGCCGACCGTGTGATGGACTCCGGTGACCTGGAAA
AGGAAAAGGGCATCACCATCCTTGCCAAGAACACCGCGATTCGTCGTAAAGGCGCTGGCAAGGACGGCAATGACCTGATT
ATCAACGTCATTGACACCCCAGGCCACGCTGACTTCGGTGGCGAAGTTGAGCGCGCACTGTCCATGGTTGACGGCGTTGT
CCTTCTGGTTGACGCATCTGAAGGCCCACTGCCTCAGACCCGATTCGTGCTTGGCAAGGCTCTTGCTGCGAAGATGCCAG
TCATCATTGCTGTGAACAAGACTGACCGCCCTGACGCTCGTATTGACGAGGTTGTTGAAGAGGCACAGGATCTGCTTCTT
GAGCTCGCATCTGCACTTGATGATGAAGAAGCAGCACAGGCAGCTGAGCAGCTTCTTGATCTGCCAGTTCTGTACACCTC
CGGTCGTGAGGGCAAGGCTTCCACTGAGAACCCAGGCAACGGCAACGTTCCTAATTCCCCAGATCTGATGCCTTTGTTTG
AGACCCTCTACGAGGTTCTCCCAGAGCCAACCGCTGACATTGATGGCCCTCTGCAGGCTCACGTCACCAACCTTGACTCT
TCCTCCTTCCTTGGTCGTATCGGCCTGGTTCGCGTTCACGCAGGTACCTTGCGTAAGGGCCAGCAGGTTGCATGGATTCA
CTACGATGAAGAAGGTAACCAGCACACCAAGACCGCTAAGATCGCAGAGCTTCTGGCTACCGTTGGCGTTGCCCGCGTTC
CTGCTACCGAAGTTGTTGCAGGTGACATCGCTGCTATCTCCGGCATCGAAGACATCATGATTGGCGATACCCTCGCGGAT
CCTGAGAACCCAGTTGCACTGCCTCGCATCACCGTTGATGAGCCAGCACTGTCCATGACCATCGGTGTGAACACCTCACC
AATGGCTGGTCGTGGCGGCGGAGACAAGCTGACCGCACGTGTGGTCAAGGCTCGTCTTGAGAACGAACTGATCGGTAACG
TGTCCCTGAAGGTCAACCCAACTGAGCGCCCAGATACCTGGGAAGTTCAGGGTCGTGGCGAAATGGCTCTGTCCATCCTC
GTTGAGACCATGCGTCGCGAAGGCTTCGAGCTCACCGTTGGTAAGCCACAGGTTGTTACCCAGACCATCGACGGCAAGCT
GCACGAGCCTTACGAGATCATCGTCATCGACGTTCCTTCCGAGTACCAGGGCAACGTGACCCAGCTGCTGGCTACCCGCA
AGGGCCTCATGCAGTCCATGTCCACCACCCCAGGTTCCGACTGGATCCGCATGGAATTCCGTATTCCTGCTCGTGGCCTG
ATTGGTTTCCGTACCCAGTTCATGACTGAAACCCGTGGTACCGGTATCGCTAACTCCTACTCTGACGGCATGGATGTTTG
GGCTGGCGAAATCAAGGGCCGCGCACACGGTTCCTTGGTTGCTGACCGTTCCGGCCAGATCACCGCTTACGCTCTGACCC
AGCTGGCAGACCGTGGTAGCTTCTTCGTTGAGCCAGGCACTGAGACCTACGAAGGTGTCGTTGTTGGTCTGAACAACCGT
GAAGAAGACATGGACATCAACCCAACCAAGGAAAAGAAGCTCACCAACATGCGTGCAGCTTCCGCAGACACCACTGTCAC
CTTGGCTAAGGCTCGGTCTCTCTCCTTGGATGAGGCACTGGAGTTCTGTGGCGTCGACGAGTGCGTCGAGGTTACCCCTG
ATGTTCTGCGCATCCGCAAGGTCATCCTGAACGCTACTGAGCGTGGCCGTGCACGTTCCCGTGCGAAGAGCCTGAACAAG
TAA

Upstream 100 bases:

>100_bases
CACAATGTGCGGAACGGGCGATAATGCGAGTACAGTGATACCGTTCTAAAACAATGGACTCGTTTTACAAGTCCTCCATA
CTTCTTTATCCGGCAGGAGA

Downstream 100 bases:

>100_bases
TTCTCTTTTAGTTAAGAGTTGCTCTGGCCCGCTGTGTCCTCTGGACGCAGCGGGCCAGTAGTATTTTGGGGGTGAGAATA
AGGTTTGGAATTCTAAGTGT

Product: GTPase involved in stress response

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MPPVTHPEFRNVAIVAHVDHGKTTLVNAMLEQSGVFSDHGEVADRVMDSGDLEKEKGITILAKNTAIRRKGAGKDGNDLI
INVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVIIAVNKTDRPDARIDEVVEEAQDLLL
ELASALDDEEAAQAAEQLLDLPVLYTSGREGKASTENPGNGNVPNSPDLMPLFETLYEVLPEPTADIDGPLQAHVTNLDS
SSFLGRIGLVRVHAGTLRKGQQVAWIHYDEEGNQHTKTAKIAELLATVGVARVPATEVVAGDIAAISGIEDIMIGDTLAD
PENPVALPRITVDEPALSMTIGVNTSPMAGRGGGDKLTARVVKARLENELIGNVSLKVNPTERPDTWEVQGRGEMALSIL
VETMRREGFELTVGKPQVVTQTIDGKLHEPYEIIVIDVPSEYQGNVTQLLATRKGLMQSMSTTPGSDWIRMEFRIPARGL
IGFRTQFMTETRGTGIANSYSDGMDVWAGEIKGRAHGSLVADRSGQITAYALTQLADRGSFFVEPGTETYEGVVVGLNNR
EEDMDINPTKEKKLTNMRAASADTTVTLAKARSLSLDEALEFCGVDECVEVTPDVLRIRKVILNATERGRARSRAKSLNK

Sequences:

>Translated_640_residues
MPPVTHPEFRNVAIVAHVDHGKTTLVNAMLEQSGVFSDHGEVADRVMDSGDLEKEKGITILAKNTAIRRKGAGKDGNDLI
INVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVIIAVNKTDRPDARIDEVVEEAQDLLL
ELASALDDEEAAQAAEQLLDLPVLYTSGREGKASTENPGNGNVPNSPDLMPLFETLYEVLPEPTADIDGPLQAHVTNLDS
SSFLGRIGLVRVHAGTLRKGQQVAWIHYDEEGNQHTKTAKIAELLATVGVARVPATEVVAGDIAAISGIEDIMIGDTLAD
PENPVALPRITVDEPALSMTIGVNTSPMAGRGGGDKLTARVVKARLENELIGNVSLKVNPTERPDTWEVQGRGEMALSIL
VETMRREGFELTVGKPQVVTQTIDGKLHEPYEIIVIDVPSEYQGNVTQLLATRKGLMQSMSTTPGSDWIRMEFRIPARGL
IGFRTQFMTETRGTGIANSYSDGMDVWAGEIKGRAHGSLVADRSGQITAYALTQLADRGSFFVEPGTETYEGVVVGLNNR
EEDMDINPTKEKKLTNMRAASADTTVTLAKARSLSLDEALEFCGVDECVEVTPDVLRIRKVILNATERGRARSRAKSLNK
>Mature_639_residues
PPVTHPEFRNVAIVAHVDHGKTTLVNAMLEQSGVFSDHGEVADRVMDSGDLEKEKGITILAKNTAIRRKGAGKDGNDLII
NVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQTRFVLGKALAAKMPVIIAVNKTDRPDARIDEVVEEAQDLLLE
LASALDDEEAAQAAEQLLDLPVLYTSGREGKASTENPGNGNVPNSPDLMPLFETLYEVLPEPTADIDGPLQAHVTNLDSS
SFLGRIGLVRVHAGTLRKGQQVAWIHYDEEGNQHTKTAKIAELLATVGVARVPATEVVAGDIAAISGIEDIMIGDTLADP
ENPVALPRITVDEPALSMTIGVNTSPMAGRGGGDKLTARVVKARLENELIGNVSLKVNPTERPDTWEVQGRGEMALSILV
ETMRREGFELTVGKPQVVTQTIDGKLHEPYEIIVIDVPSEYQGNVTQLLATRKGLMQSMSTTPGSDWIRMEFRIPARGLI
GFRTQFMTETRGTGIANSYSDGMDVWAGEIKGRAHGSLVADRSGQITAYALTQLADRGSFFVEPGTETYEGVVVGLNNRE
EDMDINPTKEKKLTNMRAASADTTVTLAKARSLSLDEALEFCGVDECVEVTPDVLRIRKVILNATERGRARSRAKSLNK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=490, Percent_Identity=26.734693877551, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI94966754, Length=135, Percent_Identity=42.2222222222222, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=37.2413793103448, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=40, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310132016, Length=114, Percent_Identity=42.9824561403509, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310110807, Length=114, Percent_Identity=42.9824561403509, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310123363, Length=114, Percent_Identity=42.9824561403509, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI217272894, Length=140, Percent_Identity=34.2857142857143, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=34.2857142857143, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI25306283, Length=169, Percent_Identity=37.8698224852071, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI25306287, Length=352, Percent_Identity=29.2613636363636, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI19923640, Length=169, Percent_Identity=37.8698224852071, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI34147630, Length=165, Percent_Identity=34.5454545454545, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI53729339, Length=285, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI53729337, Length=285, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI48994988, Length=630, Percent_Identity=45.8730158730159, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1789738, Length=500, Percent_Identity=28.4, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1788922, Length=517, Percent_Identity=27.4661508704062, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790835, Length=155, Percent_Identity=30.3225806451613, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790412, Length=267, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789737, Length=267, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=321, Percent_Identity=29.9065420560748, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17556745, Length=154, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=141, Percent_Identity=37.5886524822695, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=141, Percent_Identity=37.5886524822695, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=41.2587412587413, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17506493, Length=157, Percent_Identity=34.3949044585987, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=34.8148148148148, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17556456, Length=151, Percent_Identity=34.4370860927152, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=544, Percent_Identity=25.7352941176471, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324707, Length=145, Percent_Identity=39.3103448275862, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320593, Length=145, Percent_Identity=39.3103448275862, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323098, Length=230, Percent_Identity=34.7826086956522, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322359, Length=147, Percent_Identity=36.734693877551, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324166, Length=141, Percent_Identity=39.0070921985816, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324761, Length=263, Percent_Identity=26.2357414448669, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI78706572, Length=539, Percent_Identity=26.3450834879406, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28574573, Length=138, Percent_Identity=38.4057971014493, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24585711, Length=186, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24585713, Length=186, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24585709, Length=186, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357743, Length=167, Percent_Identity=34.1317365269461, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221458488, Length=154, Percent_Identity=41.5584415584416, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24582462, Length=139, Percent_Identity=41.0071942446043, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363316, Length=270, Percent_Identity=26.2962962962963, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864358, Length=270, Percent_Identity=26.2962962962963, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921738, Length=271, Percent_Identity=26.9372693726937, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28572034, Length=161, Percent_Identity=31.055900621118, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68996; Mature: 68865

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVTHPEFRNVAIVAHVDHGKTTLVNAMLEQSGVFSDHGEVADRVMDSGDLEKEKGITI
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEE
LAKNTAIRRKGAGKDGNDLIINVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQT
EECCCCHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHH
RFVLGKALAAKMPVIIAVNKTDRPDARIDEVVEEAQDLLLELASALDDEEAAQAAEQLLD
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
LPVLYTSGREGKASTENPGNGNVPNSPDLMPLFETLYEVLPEPTADIDGPLQAHVTNLDS
CCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
SSFLGRIGLVRVHAGTLRKGQQVAWIHYDEEGNQHTKTAKIAELLATVGVARVPATEVVA
HHHHHCEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
GDIAAISGIEDIMIGDTLADPENPVALPRITVDEPALSMTIGVNTSPMAGRGGGDKLTAR
CCHHHHCCCCHHEECCCCCCCCCCEECCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHH
VVKARLENELIGNVSLKVNPTERPDTWEVQGRGEMALSILVETMRREGFELTVGKPQVVT
HHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCCCEEEE
QTIDGKLHEPYEIIVIDVPSEYQGNVTQLLATRKGLMQSMSTTPGSDWIRMEFRIPARGL
EECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCH
IGFRTQFMTETRGTGIANSYSDGMDVWAGEIKGRAHGSLVADRSGQITAYALTQLADRGS
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCCCEEHHHHHHHHCCCC
FFVEPGTETYEGVVVGLNNREEDMDINPTKEKKLTNMRAASADTTVTLAKARSLSLDEAL
EEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCHHHHH
EFCGVDECVEVTPDVLRIRKVILNATERGRARSRAKSLNK
HHCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPVTHPEFRNVAIVAHVDHGKTTLVNAMLEQSGVFSDHGEVADRVMDSGDLEKEKGITI
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEE
LAKNTAIRRKGAGKDGNDLIINVIDTPGHADFGGEVERALSMVDGVVLLVDASEGPLPQT
EECCCCHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHH
RFVLGKALAAKMPVIIAVNKTDRPDARIDEVVEEAQDLLLELASALDDEEAAQAAEQLLD
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
LPVLYTSGREGKASTENPGNGNVPNSPDLMPLFETLYEVLPEPTADIDGPLQAHVTNLDS
CCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
SSFLGRIGLVRVHAGTLRKGQQVAWIHYDEEGNQHTKTAKIAELLATVGVARVPATEVVA
HHHHHCEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
GDIAAISGIEDIMIGDTLADPENPVALPRITVDEPALSMTIGVNTSPMAGRGGGDKLTAR
CCHHHHCCCCHHEECCCCCCCCCCEECCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHH
VVKARLENELIGNVSLKVNPTERPDTWEVQGRGEMALSILVETMRREGFELTVGKPQVVT
HHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCCCEEEE
QTIDGKLHEPYEIIVIDVPSEYQGNVTQLLATRKGLMQSMSTTPGSDWIRMEFRIPARGL
EECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCH
IGFRTQFMTETRGTGIANSYSDGMDVWAGEIKGRAHGSLVADRSGQITAYALTQLADRGS
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCCCCEEHHHHHHHHCCCC
FFVEPGTETYEGVVVGLNNREEDMDINPTKEKKLTNMRAASADTTVTLAKARSLSLDEAL
EEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCHHHHH
EFCGVDECVEVTPDVLRIRKVILNATERGRARSRAKSLNK
HHCCCCHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]