BacMap

Definition	Corynebacterium glutamicum ATCC 13032, complete genome.
Accession	NC_006958
Length	3,282,708

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The map label for this gene is yvgN [H]

Identifier: 62389936

GI number: 62389936

Start: 1099262

End: 1100065

Strand: Direct

Name: yvgN [H]

Synonym: cg1192

Alternate gene names: 62389936

Gene position: 1099262-1100065 (Clockwise)

Preceding gene: 62389935

Following gene: 62389937

Centisome position: 33.49

GC content: 52.24

Gene sequence:

>804_bases
ATGGTGGCAACCTCTCAGTTTATCGATGACAGCGAGGCTGCCCAGGCGGTACGCGCAGCTATTGTTGCAGGATACCGAAA
CATTGATACTGCCCTAGCGTATGGAAACGAGCGCGGCGTTGGCGAAGGCATTCGCACCGCTGGAGTGCCCCGCGAGGAGC
TCTTTATTTCCACCAAGCTAGCTGCAGAAATCAAAGATTACGATGGAGCAGTCGCCGCGATTGATGAGTCTTTGGCGAAA
ATTGGCTTGGATTATGTCGATCTGATGCTCATTCACTCCCCACAACCATGGAGTGATTTCCGTGGTGGGGACTATTCAGA
GGGAAACCGTGAAGCGTGGCGCGCGCTGGAAGATGCCTACAAAGCCGGAAAGATTCGATCCATTGGTGTCTCGAACTTCC
TGGAGGCCGATCTGGAGAATATCTTAGACTCCGCGACGGTTGCTCCTCACGTTAATCAGCTTCTTGTGCATGTTGGAAAC
ACCCCAAGCGAGTTAATCAGTTTCTGCGATTCCAAGGGCATTCTGGTCGAAGCATATTCACCCATCGCCCACGGAGAGAT
GCTGAAGAACCAGCAGGTCAAGGCGATTGCTGACAAGTACAACGTGAGCATTCCGCAGCTATGCATTCGGTACACAATTC
AACTGGGAACGGTGTCTTTGCCAAAGACTGCCAACCCAGATCATATGAGCTCCAATGCGCAGATCGACTTTGAAATTTCC
GAGGAAGACATGGCGGCACTTCAAGAAGTGACCGCCCGCGATTATGGCGAGCACAGCGGTTTTCCTGTGTATTCCGGCAA
GTAG

Upstream 100 bases:

>100_bases
GACCTAAAATTCATCACCTCACCGTTTTTAAGGCTTAGAAAAATAGCAGTGTTGGGATGTGAATATCCATTTATGCTGCT
GTAGTCGGCTATGTGGACGC

Downstream 100 bases:

>100_bases
AAAGATTTTTATCATGGGACAAAAAGTAACCGCAGGTCGTGACATCCTAGGAGAGTTTGCACCTAAGTCCGCTGAACTCA
ACGATGATGTCCTCTTTGGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: GR; Methylglyoxal reductase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MVATSQFIDDSEAAQAVRAAIVAGYRNIDTALAYGNERGVGEGIRTAGVPREELFISTKLAAEIKDYDGAVAAIDESLAK
IGLDYVDLMLIHSPQPWSDFRGGDYSEGNREAWRALEDAYKAGKIRSIGVSNFLEADLENILDSATVAPHVNQLLVHVGN
TPSELISFCDSKGILVEAYSPIAHGEMLKNQQVKAIADKYNVSIPQLCIRYTIQLGTVSLPKTANPDHMSSNAQIDFEIS
EEDMAALQEVTARDYGEHSGFPVYSGK

Sequences:

>Translated_267_residues
MVATSQFIDDSEAAQAVRAAIVAGYRNIDTALAYGNERGVGEGIRTAGVPREELFISTKLAAEIKDYDGAVAAIDESLAK
IGLDYVDLMLIHSPQPWSDFRGGDYSEGNREAWRALEDAYKAGKIRSIGVSNFLEADLENILDSATVAPHVNQLLVHVGN
TPSELISFCDSKGILVEAYSPIAHGEMLKNQQVKAIADKYNVSIPQLCIRYTIQLGTVSLPKTANPDHMSSNAQIDFEIS
EEDMAALQEVTARDYGEHSGFPVYSGK
>Mature_267_residues
MVATSQFIDDSEAAQAVRAAIVAGYRNIDTALAYGNERGVGEGIRTAGVPREELFISTKLAAEIKDYDGAVAAIDESLAK
IGLDYVDLMLIHSPQPWSDFRGGDYSEGNREAWRALEDAYKAGKIRSIGVSNFLEADLENILDSATVAPHVNQLLVHVGN
TPSELISFCDSKGILVEAYSPIAHGEMLKNQQVKAIADKYNVSIPQLCIRYTIQLGTVSLPKTANPDHMSSNAQIDFEIS
EEDMAALQEVTARDYGEHSGFPVYSGK

Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase family [H]

Homologues:

Organism=Homo sapiens, GI223468663, Length=266, Percent_Identity=34.2105263157895, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI291291012, Length=280, Percent_Identity=33.2142857142857, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI24497577, Length=261, Percent_Identity=32.9501915708812, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI5174391, Length=261, Percent_Identity=32.9501915708812, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI93277124, Length=273, Percent_Identity=34.7985347985348, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI4502049, Length=264, Percent_Identity=36.3636363636364, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI5174695, Length=267, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI24497583, Length=289, Percent_Identity=32.1799307958478, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI5453543, Length=270, Percent_Identity=32.962962962963, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI310109920, Length=270, Percent_Identity=32.962962962963, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI45446745, Length=270, Percent_Identity=32.962962962963, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI4503285, Length=270, Percent_Identity=32.962962962963, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI310109922, Length=258, Percent_Identity=32.9457364341085, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI300116273, Length=253, Percent_Identity=32.8063241106719, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI24497585, Length=268, Percent_Identity=31.3432835820896, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI310109924, Length=146, Percent_Identity=32.1917808219178, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI87082198, Length=254, Percent_Identity=34.6456692913386, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786400, Length=251, Percent_Identity=30.2788844621514, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788081, Length=245, Percent_Identity=32.6530612244898, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87081735, Length=191, Percent_Identity=27.7486910994764, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71998625, Length=235, Percent_Identity=36.5957446808511, Blast_Score=163, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17564128, Length=298, Percent_Identity=32.5503355704698, Blast_Score=150, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17537077, Length=274, Percent_Identity=33.9416058394161, Blast_Score=140, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17537075, Length=254, Percent_Identity=35.4330708661417, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17552492, Length=260, Percent_Identity=31.5384615384615, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17561298, Length=252, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17566692, Length=270, Percent_Identity=32.962962962963, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17537079, Length=267, Percent_Identity=31.4606741573034, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17550248, Length=263, Percent_Identity=31.5589353612167, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17561300, Length=274, Percent_Identity=29.9270072992701, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562292, Length=250, Percent_Identity=30.4, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17538386, Length=251, Percent_Identity=28.6852589641434, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320576, Length=265, Percent_Identity=38.8679245283019, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324694, Length=270, Percent_Identity=37.4074074074074, Blast_Score=164, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322556, Length=250, Percent_Identity=36, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319625, Length=285, Percent_Identity=38.2456140350877, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320079, Length=271, Percent_Identity=31.7343173431734, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6321896, Length=286, Percent_Identity=29.020979020979, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24657054, Length=263, Percent_Identity=39.5437262357414, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI20129731, Length=260, Percent_Identity=34.6153846153846, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24663317, Length=275, Percent_Identity=32.3636363636364, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21356425, Length=261, Percent_Identity=33.7164750957854, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24644950, Length=271, Percent_Identity=32.8413284132841, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24662789, Length=265, Percent_Identity=32.0754716981132, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378297, Length=291, Percent_Identity=30.5841924398625, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24662785, Length=288, Percent_Identity=32.6388888888889, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24662781, Length=256, Percent_Identity=34.765625, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45553081, Length=264, Percent_Identity=29.5454545454545, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281366140, Length=248, Percent_Identity=29.8387096774194, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: =1.1.1.283 [H]

Molecular weight: Translated: 28985; Mature: 28985

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATSQFIDDSEAAQAVRAAIVAGYRNIDTALAYGNERGVGEGIRTAGVPREELFISTKL
CCCCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHCCCCHHHHEEHHHH
AAEIKDYDGAVAAIDESLAKIGLDYVDLMLIHSPQPWSDFRGGDYSEGNREAWRALEDAY
HHHHHHCCCHHHHHHHHHHHHCHHHHHEEEEECCCCCHHCCCCCCCCCCHHHHHHHHHHH
KAGKIRSIGVSNFLEADLENILDSATVAPHVNQLLVHVGNTPSELISFCDSKGILVEAYS
HCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECC
PIAHGEMLKNQQVKAIADKYNVSIPQLCIRYTIQLGTVSLPKTANPDHMSSNAQIDFEIS
CHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCEEEEEEC
EEDMAALQEVTARDYGEHSGFPVYSGK
HHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVATSQFIDDSEAAQAVRAAIVAGYRNIDTALAYGNERGVGEGIRTAGVPREELFISTKL
CCCCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHCCCCHHHHEEHHHH
AAEIKDYDGAVAAIDESLAKIGLDYVDLMLIHSPQPWSDFRGGDYSEGNREAWRALEDAY
HHHHHHCCCHHHHHHHHHHHHCHHHHHEEEEECCCCCHHCCCCCCCCCCHHHHHHHHHHH
KAGKIRSIGVSNFLEADLENILDSATVAPHVNQLLVHVGNTPSELISFCDSKGILVEAYS
HCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECC
PIAHGEMLKNQQVKAIADKYNVSIPQLCIRYTIQLGTVSLPKTANPDHMSSNAQIDFEIS
CHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCEEEEEEC
EEDMAALQEVTARDYGEHSGFPVYSGK
HHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]