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The map label for this gene is arcB [H]

Identifier: 62389921

GI number: 62389921

Start: 1087556

End: 1088389

Strand: Direct

Name: arcB [H]

Synonym: cg1174

Alternate gene names: 62389921

Gene position: 1087556-1088389 (Clockwise)

Preceding gene: 62389920

Following gene: 62389925

Centisome position: 33.13

GC content: 62.11

Gene sequence:

>834_bases
GTGAGCTCGGTGGCCAGAAAACATCTGCTCTCCCTGGCAGACTGGAACAGAGGCGAGCTTGAGGCATTATTCGAGCTCGC
GGAGCAGTATGAAGCTGGCGGTGGGCCACGATTCGATGGTGCCGCGGCGATGTTCTTCCCGCCGACGAGTTTGCGTACAC
GGCTCTCATTCGAGCGTGGGGCAACGGCAATGGGACTCCAGCCGATCACGTTCCCGTCAGACAGCCTGGACAAGGACGAA
GATCTCGTCGACGTCGTCGGCTATCTCTCGCAGTGGGCTGATGTCGTTGTCGTCCGACACCCGCAATTGACGGCGCTTCA
GCGGTTGGCGTCAGCGGATGCAGCGCCCGTGATCAACGCGATGACGAGTGAGAACCATCCGTGCGAAGTCCTCTCGGACT
TGTATGCGCTGTCTCGTCACCATGACATTTCGGCCCTGCGGTACCTGTTTGTCGGTGGCGATGGCAACATCGCCAGGGCC
TGGTGGGAGGCGGCCCAAGCGTTCGGCCTCGAGATGCGGCAGAGTTGTCCTGAAGAGCTGCGTGTCGTCGGGATGCCGTG
GGAGGAGAACCTGCCGCATGCAATTGCATCAGCGGATGTCGTGCTGACGGATGGGCCAGGTAGACATGCGGAGTTACTCG
AGCCGTATCGTGTGACCGCTGCGTTGTTGGATCGCGCGCCCCGTGGAGTGCGGCTCGCGCCCTGCCCGCCGTTCATCCGC
GGGCGCGAAGTGAGCGCCGATGCGATCGAGCATCCGGCGTTCGTCGGGTACTCGTTCAAGCGTCATCTCATGCCGGTTCA
GCAGGCGATTCTGGCTCGGTCGATCAATGCGTAG

Upstream 100 bases:

>100_bases
ACCCGCAGTTCTGGCTGAGCCTTCAGACTCAGTACGAGTTGGAGCTCGATCGCGACGCCGGTGCAGCGACTTACGCACAG
ATCACGCCGCTGAAGGTCGC

Downstream 100 bases:

>100_bases
CGGTTTTCGGTGTCGGAACTCGGTGGAGTTTCGGTTTAACGTCTAGTCGCGTTCCGGTTCAACCTCTTGCACAAGCGTCG
GCCCCTGAAAGGAGCCGGCG

Product: ornithine carbamoyltransferase protein

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSSVARKHLLSLADWNRGELEALFELAEQYEAGGGPRFDGAAAMFFPPTSLRTRLSFERGATAMGLQPITFPSDSLDKDE
DLVDVVGYLSQWADVVVVRHPQLTALQRLASADAAPVINAMTSENHPCEVLSDLYALSRHHDISALRYLFVGGDGNIARA
WWEAAQAFGLEMRQSCPEELRVVGMPWEENLPHAIASADVVLTDGPGRHAELLEPYRVTAALLDRAPRGVRLAPCPPFIR
GREVSADAIEHPAFVGYSFKRHLMPVQQAILARSINA

Sequences:

>Translated_277_residues
MSSVARKHLLSLADWNRGELEALFELAEQYEAGGGPRFDGAAAMFFPPTSLRTRLSFERGATAMGLQPITFPSDSLDKDE
DLVDVVGYLSQWADVVVVRHPQLTALQRLASADAAPVINAMTSENHPCEVLSDLYALSRHHDISALRYLFVGGDGNIARA
WWEAAQAFGLEMRQSCPEELRVVGMPWEENLPHAIASADVVLTDGPGRHAELLEPYRVTAALLDRAPRGVRLAPCPPFIR
GREVSADAIEHPAFVGYSFKRHLMPVQQAILARSINA
>Mature_276_residues
SSVARKHLLSLADWNRGELEALFELAEQYEAGGGPRFDGAAAMFFPPTSLRTRLSFERGATAMGLQPITFPSDSLDKDED
LVDVVGYLSQWADVVVVRHPQLTALQRLASADAAPVINAMTSENHPCEVLSDLYALSRHHDISALRYLFVGGDGNIARAW
WEAAQAFGLEMRQSCPEELRVVGMPWEENLPHAIASADVVLTDGPGRHAELLEPYRVTAALLDRAPRGVRLAPCPPFIRG
REVSADAIEHPAFVGYSFKRHLMPVQQAILARSINA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=147, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=25.4491017964072, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=25.2252252252252, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367364, Length=306, Percent_Identity=26.1437908496732, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 30421; Mature: 30290

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVARKHLLSLADWNRGELEALFELAEQYEAGGGPRFDGAAAMFFPPTSLRTRLSFERG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCC
ATAMGLQPITFPSDSLDKDEDLVDVVGYLSQWADVVVVRHPQLTALQRLASADAAPVINA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHCCCCHHHHHH
MTSENHPCEVLSDLYALSRHHDISALRYLFVGGDGNIARAWWEAAQAFGLEMRQSCPEEL
HCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RVVGMPWEENLPHAIASADVVLTDGPGRHAELLEPYRVTAALLDRAPRGVRLAPCPPFIR
EEECCCCHHCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
GREVSADAIEHPAFVGYSFKRHLMPVQQAILARSINA
CCCCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSVARKHLLSLADWNRGELEALFELAEQYEAGGGPRFDGAAAMFFPPTSLRTRLSFERG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCC
ATAMGLQPITFPSDSLDKDEDLVDVVGYLSQWADVVVVRHPQLTALQRLASADAAPVINA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHCCCCHHHHHH
MTSENHPCEVLSDLYALSRHHDISALRYLFVGGDGNIARAWWEAAQAFGLEMRQSCPEEL
HCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RVVGMPWEENLPHAIASADVVLTDGPGRHAELLEPYRVTAALLDRAPRGVRLAPCPPFIR
EEECCCCHHCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCC
GREVSADAIEHPAFVGYSFKRHLMPVQQAILARSINA
CCCCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]