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The map label for this gene is engD [H]

Identifier: 62389918

GI number: 62389918

Start: 1085849

End: 1086934

Strand: Direct

Name: engD [H]

Synonym: cg1171

Alternate gene names: 62389918

Gene position: 1085849-1086934 (Clockwise)

Preceding gene: 62389912

Following gene: 62389919

Centisome position: 33.08

GC content: 55.71

Gene sequence:

>1086_bases
GTGACCCTTACTCTTGGAATCGTCGGCCTGCCCAACGTTGGCAAGTCCACCCTGTTCAACGCCCTGACTCGCAATGACGT
GCTCGCAGCGAACTACCCGTTCGCCACCATCGAGCCAAACGTGGGCCTTGTCGAGCTTCCAGACGCTCGCCTTGAACGCC
TTTCTGAAATCTTCGGCTCTGAGCGCATCCTGCCAGCAACCGTGTCTTTCGTTGACATCGCCGGAATCGTTAAGGGAGCT
TCCGAAGGCGAAGGAATGGGCAACGCTTTCCTTGCCAACATCCGCGAAGCAGACGCTATCTGTCAGGTTGTGCGCGCATT
CGCTGACGAAAACGTCATTCACGTCGATGGTGAAGTTAACCCAGCAACCGATATCTCTGTGATCAACACCGAGCTGATCC
TCGCCGACCTGCAGACCGTGGAAAAAGCACTCCCACGCCTCGAAAAGGATGCACGCAAAGACAAGGGACTTGGCGAAGTC
GTAGATGAGACCAAAAAAGCCCTTGCGATCTTGAGCGATGACCGCACCTTGTTCTCTGCAGCAAAAGCTGGCGACATTGA
TCTGGCCCTCCTGCGCGATCTCCACCTGATGACAGCAAAGCCTTTCCTCTACGTCTTCAACTCCGACGAAAAAGTGCTCA
CCGACGACGCCAAGAAGGACGAACTCCGCGCACTAGTCGCGCCAGCAGACTGCGTATTCCTTGACGCACAAACTGAAACC
GAACTTCTTGAACTCGAAGAAGACGAAGCAGCAGAACTCCTCGAAGCTGTAGGCCAAACGGAACCAGGCCTACACTCCCT
CGCACGTGCAGGATTTGAAACCCTCGGACTACAGACCTACCTCACCGCGGGTCCTAAGGAATCACGCGCCTGGACCATCC
ACAAGGGCGACACCGCTCCACAGGCAGCAGGCGTTATCCATTCTGACTTCGAACGCGGCTTCATCAAGGCTGAAATCGTC
TCCTTCGAAGATCTTGACGCTGCTGGTTCCATGGCGGAAGCCAAGGCCCAGGGCAAAGTCCGCCAAGAAGGTAAGGACTA
CGTGATGGTCGATGGCGACGTTGTGGAGTTCCGGTTTAACGTCTAG

Upstream 100 bases:

>100_bases
AGCGAAATTTCACCTTTTTGGAGGCAGTCGACAATGCTCTGGGCACTGTTTTGTGCCTCCTGATTAGGTTCTTACCCAAC
GATTGCTAGGATATGTGCCT

Downstream 100 bases:

>100_bases
CGTTATTGACGCTCCTCGTTATACGCTGGTCTCGTGATCAGATCGTTCGCCGACCGCGACACCGAGTTGGTCTGGTTGCG
TGAAGGTGCGAAACGCGTCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLERLSEIFGSERILPATVSFVDIAGIVKGA
SEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVNPATDISVINTELILADLQTVEKALPRLEKDARKDKGLGEV
VDETKKALAILSDDRTLFSAAKAGDIDLALLRDLHLMTAKPFLYVFNSDEKVLTDDAKKDELRALVAPADCVFLDAQTET
ELLELEEDEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAPQAAGVIHSDFERGFIKAEIV
SFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFRFNV

Sequences:

>Translated_361_residues
MTLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLERLSEIFGSERILPATVSFVDIAGIVKGA
SEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVNPATDISVINTELILADLQTVEKALPRLEKDARKDKGLGEV
VDETKKALAILSDDRTLFSAAKAGDIDLALLRDLHLMTAKPFLYVFNSDEKVLTDDAKKDELRALVAPADCVFLDAQTET
ELLELEEDEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAPQAAGVIHSDFERGFIKAEIV
SFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFRFNV
>Mature_360_residues
TLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLERLSEIFGSERILPATVSFVDIAGIVKGAS
EGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVNPATDISVINTELILADLQTVEKALPRLEKDARKDKGLGEVV
DETKKALAILSDDRTLFSAAKAGDIDLALLRDLHLMTAKPFLYVFNSDEKVLTDDAKKDELRALVAPADCVFLDAQTETE
LLELEEDEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAPQAAGVIHSDFERGFIKAEIVS
FEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=373, Percent_Identity=40.7506702412869, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI58761502, Length=188, Percent_Identity=39.8936170212766, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1787454, Length=372, Percent_Identity=50.8064516129032, Blast_Score=348, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=38.5245901639344, Blast_Score=253, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=39.4101876675603, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=391, Percent_Identity=34.2710997442455, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321649, Length=114, Percent_Identity=38.5964912280702, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.6666666666667, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.6666666666667, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.6666666666667, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=39.6969696969697, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24585318, Length=141, Percent_Identity=31.2056737588652, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38955; Mature: 38824

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLERLSEIFGS
CEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCHHHHHHHHHHHCC
ERILPATVSFVDIAGIVKGASEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVN
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PATDISVINTELILADLQTVEKALPRLEKDARKDKGLGEVVDETKKALAILSDDRTLFSA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCHHHHH
AKAGDIDLALLRDLHLMTAKPFLYVFNSDEKVLTDDAKKDELRALVAPADCVFLDAQTET
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHEEECCCCEEEEECCCCC
ELLELEEDEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAP
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCEEEEECCCCCCCEEEEECCCCCC
QAAGVIHSDFERGFIKAEIVSFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFRFN
HHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCHHHCCCCEEEECCEEEEEEEC
V
C
>Mature Secondary Structure 
TLTLGIVGLPNVGKSTLFNALTRNDVLAANYPFATIEPNVGLVELPDARLERLSEIFGS
EEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCHHHHHHHHHHHCC
ERILPATVSFVDIAGIVKGASEGEGMGNAFLANIREADAICQVVRAFADENVIHVDGEVN
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PATDISVINTELILADLQTVEKALPRLEKDARKDKGLGEVVDETKKALAILSDDRTLFSA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCHHHHH
AKAGDIDLALLRDLHLMTAKPFLYVFNSDEKVLTDDAKKDELRALVAPADCVFLDAQTET
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHEEECCCCEEEEECCCCC
ELLELEEDEAAELLEAVGQTEPGLHSLARAGFETLGLQTYLTAGPKESRAWTIHKGDTAP
HHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCEEEEECCCCCCCEEEEECCCCCC
QAAGVIHSDFERGFIKAEIVSFEDLDAAGSMAEAKAQGKVRQEGKDYVMVDGDVVEFRFN
HHHCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCHHHCCCCEEEECCEEEEEEEC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]