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The map label for this gene is pabAB [H]

Identifier: 62389885

GI number: 62389885

Start: 1053491

End: 1055353

Strand: Direct

Name: pabAB [H]

Synonym: cg1134

Alternate gene names: 62389885

Gene position: 1053491-1055353 (Clockwise)

Preceding gene: 62389884

Following gene: 62389886

Centisome position: 32.09

GC content: 53.41

Gene sequence:

>1863_bases
ATGCGCGTTTTAATTATTGATAATTATGATTCTTTCACGTTTAATCTCGCCACCTATGTGGAAGAGGTTACGGGTCAGGC
ACCTGTGGTGGTGCCTAATGATCAAGAAATAGATGAGATGCTTTTCGACGCCGTCATCCTCTCACCTGGCCCGGGCCACG
CCGGCGTTGCGGCTGATTTTGGTATCTGTGCAGGCGTCATTGAGCGTGCACGCGTTCCGATTTTGGGTGTGTGTTTAGGC
CACCAGGGCATTGCGTTGGCCTATGGCGGTGATGTTGATTTGGCGCCCAGGCCGGTCCACGGTGAGGTTTCGCAGATCAC
CCATGATGGTTCAGGTTTATTTGCAGGCATCCCTGAAACGTTTGAGGCGGTGCGTTATCACTCGATGGTGGCAACCCGCT
TGCCGGAGTCATTGAAAGCTACAGCTACCAGCGATGATGGTTTGATCATGGCATTGGCACATGAAGTGCTTCCGCAGTGG
GGTGTGCAATTTCATCCGGAATCTATTGGTGGACAATTCGGCCATCAGATCATTAAGAACTTCCTTAATTTAGCGCGCAC
ATATCGCTGGCAACTCACGGAGAAAACTATTCCGCTCAGCGTTGATTCAGCAGCGGTTTTTGAAACATTCTTTGCCCATT
CCTCCCATGCTTTTTGGCTCGATGATGCCCAAGGAACCAGCTATCTTGGTGATGCCAGCGGTCCTCTCGCACGCACAAAA
ACCCATAATGTCGGCGAGGGGGATTTCTTCACCTGGCTAAAGGAGGATCTCGCCGCCAACTCAGTTGCGCCCGGTCAAGG
TTTTCGTCTTGGCTGGGTTGGTTACGTTGGTTATGAGCTTAAAGCGGAAGCTGGCGCACGGGCTGCGCACACTTCGAGTC
TTCCGGATGCGCACCTCATTTTTGCCGATCGCGCCATCGCAGTGGAATCGGATCAGGTTCGGTTGCTGGCGTTGGGGGAG
CAGGACGAGTGGTTTGAAGAAACCATCAAGAAGCTGCATAATCTTGTCGCCCCGCGGATACCTGCGTCCGGACACCTCGC
TTTGCAGGTTCGAGATTCCAAAGATGAGTATCTCGACAAAATTCGCAGAGCCCAGGAGCTGATTACTCGCGGCGAATCGT
ATGAAATCTGCCTGACCACAAAACTTCAGGGCACCACTGATGTGGCCCCTCTGGCTGCCTATCTAGCACTGCGTGGGGCC
AATCCCACCGCATATGGTGCGTATCTTCAGCTGGGGGATACCTCTATTTTGAGTTCCTCGCCGGAGCGGTTCATCACCAT
TGATTCGGCAGGGTATGTGGAATCAAAGCCCATTAAAGGCACCAGGCCGCGTGGGCGAACAGCGCAAGAAGACCAAGAAA
TCATTGCTGAGCTGCGCAGTAATCCTAAAGATCGTGCAGAAAACTTGATGATCGTGGATTTGGTCCGCAACGACTTAGCC
CGCGGCGCTTTGCCCACCACAGTTAAAACATCCAAGCTTTTCGACGTCGAAACCTACGCCACAGTCCACCAACTTGTCAG
CACCGTCTCTGCAGAGTTGGGGCCACGCAGTCCGATTGAGTGCGTGCGCGCAGCATTCCCCGGTGGTTCGATGACTGGTG
CCCCAAAGCTGCGCACCATGGAGATCATCGATGAGCTGGAGGCAGCTCCTCGCGGTATTTACTCAGGTGGCTTGGGATAT
TTTTCCCTCGACGGCGCAGTTGATCTCTCCATGGTGATCAGAACTCTCGTCATCCAGAACAATCACGTGGAGTACGGAGT
GGGCGGTGCACTTCTTGCTCTGTCTGATCCGGAGGCTGAGTGGGAGGAAATCCGCGTTAAATCACGGCCTCTGCTGAATT
TGTTTGGGGTTGAATTCCCATGA

Upstream 100 bases:

>100_bases
TCGTCTAAGTTTTTCTTTGAGTTTTCATATGTAGAAGGCATCGTCGGCTTCGGCCTGGCGGTGCTTTTCTCGTTGTTTTG
TGGTTTTGTCAGAGGATGTC

Downstream 100 bases:

>100_bases
CGTACCTCGTGTGGGACGGTGCAACACTCGTAGAAGGCGCGCTGGAATCAACACCCACAGTTGTTGATTCCTACCTAGCC
AAAGACCACCGCGTGGTGCG

Product: PARA-aminobenzoate synthase component I and II

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDEMLFDAVILSPGPGHAGVAADFGICAGVIERARVPILGVCLG
HQGIALAYGGDVDLAPRPVHGEVSQITHDGSGLFAGIPETFEAVRYHSMVATRLPESLKATATSDDGLIMALAHEVLPQW
GVQFHPESIGGQFGHQIIKNFLNLARTYRWQLTEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLIFADRAIAVESDQVRLLALGE
QDEWFEETIKKLHNLVAPRIPASGHLALQVRDSKDEYLDKIRRAQELITRGESYEICLTTKLQGTTDVAPLAAYLALRGA
NPTAYGAYLQLGDTSILSSSPERFITIDSAGYVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTMEIIDELEAAPRGIYSGGLGY
FSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAEWEEIRVKSRPLLNLFGVEFP

Sequences:

>Translated_620_residues
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDEMLFDAVILSPGPGHAGVAADFGICAGVIERARVPILGVCLG
HQGIALAYGGDVDLAPRPVHGEVSQITHDGSGLFAGIPETFEAVRYHSMVATRLPESLKATATSDDGLIMALAHEVLPQW
GVQFHPESIGGQFGHQIIKNFLNLARTYRWQLTEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLIFADRAIAVESDQVRLLALGE
QDEWFEETIKKLHNLVAPRIPASGHLALQVRDSKDEYLDKIRRAQELITRGESYEICLTTKLQGTTDVAPLAAYLALRGA
NPTAYGAYLQLGDTSILSSSPERFITIDSAGYVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTMEIIDELEAAPRGIYSGGLGY
FSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAEWEEIRVKSRPLLNLFGVEFP
>Mature_620_residues
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDEMLFDAVILSPGPGHAGVAADFGICAGVIERARVPILGVCLG
HQGIALAYGGDVDLAPRPVHGEVSQITHDGSGLFAGIPETFEAVRYHSMVATRLPESLKATATSDDGLIMALAHEVLPQW
GVQFHPESIGGQFGHQIIKNFLNLARTYRWQLTEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLIFADRAIAVESDQVRLLALGE
QDEWFEETIKKLHNLVAPRIPASGHLALQVRDSKDEYLDKIRRAQELITRGESYEICLTTKLQGTTDVAPLAAYLALRGA
NPTAYGAYLQLGDTSILSSSPERFITIDSAGYVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTMEIIDELEAAPRGIYSGGLGY
FSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAEWEEIRVKSRPLLNLFGVEFP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=361, Percent_Identity=37.6731301939058, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1787518, Length=363, Percent_Identity=30.8539944903581, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1789760, Length=192, Percent_Identity=44.2708333333333, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787517, Length=193, Percent_Identity=37.3056994818653, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786809, Length=263, Percent_Identity=24.7148288973384, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082077, Length=261, Percent_Identity=24.904214559387, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=392, Percent_Identity=30.1020408163265, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=391, Percent_Identity=31.2020460358056, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=40.3141361256544, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6323873, Length=182, Percent_Identity=29.6703296703297, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67264; Mature: 67264

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDEMLFDAVILSPGPGHAGVAADF
CEEEEEECCCCCEEHHHHHHHHHCCCCCEEECCCCHHHHHHHHHEEECCCCCCCCCHHHH
GICAGVIERARVPILGVCLGHQGIALAYGGDVDLAPRPVHGEVSQITHDGSGLFAGIPET
HHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEEECCCCEEECCHHH
FEAVRYHSMVATRLPESLKATATSDDGLIMALAHEVLPQWGVQFHPESIGGQFGHQIIKN
HHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHCHHHHHHHHHH
FLNLARTYRWQLTEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
HHHHHHHHEEEEECCCCCEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLI
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECEEEECCCCCCHHCCCCCCCCEEE
FADRAIAVESDQVRLLALGEQDEWFEETIKKLHNLVAPRIPASGHLALQVRDSKDEYLDK
EECCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHH
IRRAQELITRGESYEICLTTKLQGTTDVAPLAAYLALRGANPTAYGAYLQLGDTSILSSS
HHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHCCC
PERFITIDSAGYVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
CCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEEEEHHHHHHH
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTM
CCCCCCCEECCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHH
EIIDELEAAPRGIYSGGLGYFSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAE
HHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCC
WEEIRVKSRPLLNLFGVEFP
HHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDEMLFDAVILSPGPGHAGVAADF
CEEEEEECCCCCEEHHHHHHHHHCCCCCEEECCCCHHHHHHHHHEEECCCCCCCCCHHHH
GICAGVIERARVPILGVCLGHQGIALAYGGDVDLAPRPVHGEVSQITHDGSGLFAGIPET
HHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEEECCCCEEECCHHH
FEAVRYHSMVATRLPESLKATATSDDGLIMALAHEVLPQWGVQFHPESIGGQFGHQIIKN
HHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHCHHHHHHHHHH
FLNLARTYRWQLTEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
HHHHHHHHEEEEECCCCCEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLI
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEECEEEECCCCCCHHCCCCCCCCEEE
FADRAIAVESDQVRLLALGEQDEWFEETIKKLHNLVAPRIPASGHLALQVRDSKDEYLDK
EECCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHH
IRRAQELITRGESYEICLTTKLQGTTDVAPLAAYLALRGANPTAYGAYLQLGDTSILSSS
HHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHCCC
PERFITIDSAGYVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
CCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEEEEHHHHHHH
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTM
CCCCCCCEECCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHH
EIIDELEAAPRGIYSGGLGYFSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAE
HHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCC
WEEIRVKSRPLLNLFGVEFP
HHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]