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The map label for this gene is mmpL2 [H]

Identifier: 62389814

GI number: 62389814

Start: 979835

End: 982210

Strand: Reverse

Name: mmpL2 [H]

Synonym: cg1054

Alternate gene names: 62389814

Gene position: 982210-979835 (Counterclockwise)

Preceding gene: 62389817

Following gene: 62389813

Centisome position: 29.92

GC content: 54.84

Gene sequence:

>2376_bases
GTGGCGAAATTCCTGTATAAGTTAGGCTCCACGGCCTATCAAAAGAAATGGCCGTTTCTTGCGGTCTGGCTCGTGATTCT
CATAGGTATCACGACGCTGGCGGGGCTGTATGCCAAGCCAACGTCGAGTAGCTTCTCTATCCCTGGTCTTGATTCTGTCA
CGACCATGGAGAAGATGCAGGAGCGTTTCCCTGGTTCGGATGATGCAACATCGGCTCCCACTGGTTCTGTCGTCATTCAG
GCACCGGAAGGCAAGACCCTCACTGATCCTGAGGTTGGGGCTGAAGTAAACCAGATGCTTGATGAGGTTCGGGCGACTGG
TGTGCTGAAGGATGCTGATTCCGTTGTGGATCCTGTGTTGGCTGCGCAGGGTGTGGCTGCTCAGATGACCCCAGCCCTGG
AGGCTCAGGGTGTACCTGCGGAGAAGATCGCCGCAGATATTGAGTCGATTAGTCCACTGAGTGCAGATGAGACTACCGGC
ATCATCTCGATGACTTTTGATGCAGATTCTGCCATGGATATATCCGCAGAGGATCGTGAGAAGGTCACCAATATTCTTGA
TGAATACGATGACGGCGATCTGACTGTTGTCTACAACGGCAACGTGTTTGGCGCAGCTGCAACCAGCTTGGACATGACCT
CTGAGCTCATCGGCCTGCTGGTGGCTGCGGTCGTTCTTATCGTGACCTTCGGTTCGTTCATCGCTGCCGGTATGCCGCTG
ATCTCTGCAATCATTGGTGTCGGAATCGGCATCATGGGCATTCAGTTAGCCACGGCGTTTACTGATTCGGTCAATGACAT
GACTCCTACCCTGGCGTCGATGATTGGTCTGGCTGTCGGTATCGACTACGCGCTATTTATCGTGTCCCGTTTCCGCAATG
AGTTGATTTCTCAGACTGGCGCTAATGATCTGGAGCCAAAGGAATTGGCTGAGCGTCTGCGCACCATGCCGTTGGCTGCT
CGTGCGCATGCGATGGGAATGGCTGTGGGCACTGCGGGTTCTGCGGTTGTATTCGCGGGTACCACGGTGCTGATCGCTCT
GGTTGCTCTGTCGATCATTAATATTCCATTTCTAACCGTGATGGCCATTGCTGCCGCAATCACCGTTGCCATCGCAGTTC
TGGTTGCTCTGTCCTTCCTCCCAGCTCTGCTTGGCCTGCTTGGCACTCGCATCTTCGCAGCACGCGTGCCTGGACCTAAG
GTTCCGGATCCTGAGGACGAGAAGCCAACGATGGGTCTGAAGTGGGTCCGCCTTGTGCGCAAGATGCCGGTGGCTTACCT
GCTGGTTGGCGTCGTTTTGCTTGGTGCAATCGCAATTCCTGCGACCAATATGCGCCTGGCCATGCCGACTGATGGCACCT
CCACGCTGGGCACCGCGCCGCGCACGGCGTATGACATGACGGCAGATGCGTTCGGCCCGGGCCGCAACGCGCCCATGATT
GCGCTTATCGACGCAACCGACGTCCCTGAGGAAGAACGCCCATTGGTGTTTGGACAGGCGGTGGAGCAATTCTTGAACAC
TGATGGTGTGAAGAATGCTCAGATCACTCAGACCACGGAGAATTTCGATACCGCGCAGATCCTGATTACCCCAGAATTTG
ATGCGATCGATGAGCGCACCTCTGAGACTCTCGCAACTCTTCGTGCAGATGCTGAGACCTTCGCTGATGACACCGGCGCG
ACGTATGGCATTACTGGCGTCACCCCAATTTACGATGACATCTCTGCTCGCCTCGGCGACGTCCTGGTTCCTTACGTTCT
GATCGTTTTGGTTCTAGCGTTCCTCGTGCTGTTGCTCGTGTTCCGGTCCATTTGGGTCCCATTGATCGCGGCTCTGGGCT
TTGGCTTGTCAGTTCTGGCTACCTTTGGTGCTACCGTGGCGATCTTCCAAGAAGGTGCTTTCGGCATCATCGACGATCCT
CAGCCACTGCTGTCCTTCTTGCCGATCATGCTCATCGGCCTGGTATTTGGTCTGGCCATGGATTACCAGATCTTCCTCGT
TACTCGTATGCGTGAGGGCTTCACCAAGGGCAAGACTGCGGGCAACGCAACGTCGAATGGTTTCAAGCACGGTGCCCGCG
TGGTCACTGCTGCGGCGCTGATCATGGTGTCTGTGTTCGCGGCATTCATAGCGCAGGACATGGCGTTTATTAAGACCATG
GGCTTTGCTCTGGCCGTTGCTGTGTTCTTCGATGCCTTCGTTGTTCGCATGATGATTATCCCTGCAACAATGTTCCTGCT
TGATGACAAGGCTTGGTGGCTACCTAAGTGGTTGGATAAGATTCTTCCCAACGTTGATGTTGAAGGTGAGGGTCTTAGTG
AACTACATGAGGCTCGCACCGAGGAACTGAAGGAAAATGTAGGTGTCGGGGCTTAG

Upstream 100 bases:

>100_bases
TGTGCAAAATTGCATTCAGGCTGAAAAATTCCTAAAGGGACTCCGTCCGAATAATTGGAAAGCCCAGAAGAACAGTCAAC
TCCTAGATTAAAGGATAATC

Downstream 100 bases:

>100_bases
AGAAACAAAAAAGGCTGCTACGCGGACAGCATTGTCACGTGCTGCTGCGGAGATCGCCTTGATGGAAGGCCCTGAGGCGT
TCACGGTTGCGGCCATTGCA

Product: RND superfamily drug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MAKFLYKLGSTAYQKKWPFLAVWLVILIGITTLAGLYAKPTSSSFSIPGLDSVTTMEKMQERFPGSDDATSAPTGSVVIQ
APEGKTLTDPEVGAEVNQMLDEVRATGVLKDADSVVDPVLAAQGVAAQMTPALEAQGVPAEKIAADIESISPLSADETTG
IISMTFDADSAMDISAEDREKVTNILDEYDDGDLTVVYNGNVFGAAATSLDMTSELIGLLVAAVVLIVTFGSFIAAGMPL
ISAIIGVGIGIMGIQLATAFTDSVNDMTPTLASMIGLAVGIDYALFIVSRFRNELISQTGANDLEPKELAERLRTMPLAA
RAHAMGMAVGTAGSAVVFAGTTVLIALVALSIINIPFLTVMAIAAAITVAIAVLVALSFLPALLGLLGTRIFAARVPGPK
VPDPEDEKPTMGLKWVRLVRKMPVAYLLVGVVLLGAIAIPATNMRLAMPTDGTSTLGTAPRTAYDMTADAFGPGRNAPMI
ALIDATDVPEEERPLVFGQAVEQFLNTDGVKNAQITQTTENFDTAQILITPEFDAIDERTSETLATLRADAETFADDTGA
TYGITGVTPIYDDISARLGDVLVPYVLIVLVLAFLVLLLVFRSIWVPLIAALGFGLSVLATFGATVAIFQEGAFGIIDDP
QPLLSFLPIMLIGLVFGLAMDYQIFLVTRMREGFTKGKTAGNATSNGFKHGARVVTAAALIMVSVFAAFIAQDMAFIKTM
GFALAVAVFFDAFVVRMMIIPATMFLLDDKAWWLPKWLDKILPNVDVEGEGLSELHEARTEELKENVGVGA

Sequences:

>Translated_791_residues
MAKFLYKLGSTAYQKKWPFLAVWLVILIGITTLAGLYAKPTSSSFSIPGLDSVTTMEKMQERFPGSDDATSAPTGSVVIQ
APEGKTLTDPEVGAEVNQMLDEVRATGVLKDADSVVDPVLAAQGVAAQMTPALEAQGVPAEKIAADIESISPLSADETTG
IISMTFDADSAMDISAEDREKVTNILDEYDDGDLTVVYNGNVFGAAATSLDMTSELIGLLVAAVVLIVTFGSFIAAGMPL
ISAIIGVGIGIMGIQLATAFTDSVNDMTPTLASMIGLAVGIDYALFIVSRFRNELISQTGANDLEPKELAERLRTMPLAA
RAHAMGMAVGTAGSAVVFAGTTVLIALVALSIINIPFLTVMAIAAAITVAIAVLVALSFLPALLGLLGTRIFAARVPGPK
VPDPEDEKPTMGLKWVRLVRKMPVAYLLVGVVLLGAIAIPATNMRLAMPTDGTSTLGTAPRTAYDMTADAFGPGRNAPMI
ALIDATDVPEEERPLVFGQAVEQFLNTDGVKNAQITQTTENFDTAQILITPEFDAIDERTSETLATLRADAETFADDTGA
TYGITGVTPIYDDISARLGDVLVPYVLIVLVLAFLVLLLVFRSIWVPLIAALGFGLSVLATFGATVAIFQEGAFGIIDDP
QPLLSFLPIMLIGLVFGLAMDYQIFLVTRMREGFTKGKTAGNATSNGFKHGARVVTAAALIMVSVFAAFIAQDMAFIKTM
GFALAVAVFFDAFVVRMMIIPATMFLLDDKAWWLPKWLDKILPNVDVEGEGLSELHEARTEELKENVGVGA
>Mature_790_residues
AKFLYKLGSTAYQKKWPFLAVWLVILIGITTLAGLYAKPTSSSFSIPGLDSVTTMEKMQERFPGSDDATSAPTGSVVIQA
PEGKTLTDPEVGAEVNQMLDEVRATGVLKDADSVVDPVLAAQGVAAQMTPALEAQGVPAEKIAADIESISPLSADETTGI
ISMTFDADSAMDISAEDREKVTNILDEYDDGDLTVVYNGNVFGAAATSLDMTSELIGLLVAAVVLIVTFGSFIAAGMPLI
SAIIGVGIGIMGIQLATAFTDSVNDMTPTLASMIGLAVGIDYALFIVSRFRNELISQTGANDLEPKELAERLRTMPLAAR
AHAMGMAVGTAGSAVVFAGTTVLIALVALSIINIPFLTVMAIAAAITVAIAVLVALSFLPALLGLLGTRIFAARVPGPKV
PDPEDEKPTMGLKWVRLVRKMPVAYLLVGVVLLGAIAIPATNMRLAMPTDGTSTLGTAPRTAYDMTADAFGPGRNAPMIA
LIDATDVPEEERPLVFGQAVEQFLNTDGVKNAQITQTTENFDTAQILITPEFDAIDERTSETLATLRADAETFADDTGAT
YGITGVTPIYDDISARLGDVLVPYVLIVLVLAFLVLLLVFRSIWVPLIAALGFGLSVLATFGATVAIFQEGAFGIIDDPQ
PLLSFLPIMLIGLVFGLAMDYQIFLVTRMREGFTKGKTAGNATSNGFKHGARVVTAAALIMVSVFAAFIAQDMAFIKTMG
FALAVAVFFDAFVVRMMIIPATMFLLDDKAWWLPKWLDKILPNVDVEGEGLSELHEARTEELKENVGVGA

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 83698; Mature: 83567

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFLYKLGSTAYQKKWPFLAVWLVILIGITTLAGLYAKPTSSSFSIPGLDSVTTMEKMQ
CHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ERFPGSDDATSAPTGSVVIQAPEGKTLTDPEVGAEVNQMLDEVRATGVLKDADSVVDPVL
HHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAQGVAAQMTPALEAQGVPAEKIAADIESISPLSADETTGIISMTFDADSAMDISAEDRE
HHCCCHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
KVTNILDEYDDGDLTVVYNGNVFGAAATSLDMTSELIGLLVAAVVLIVTFGSFIAAGMPL
HHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAIIGVGIGIMGIQLATAFTDSVNDMTPTLASMIGLAVGIDYALFIVSRFRNELISQTG
HHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANDLEPKELAERLRTMPLAARAHAMGMAVGTAGSAVVFAGTTVLIALVALSIINIPFLTV
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
MAIAAAITVAIAVLVALSFLPALLGLLGTRIFAARVPGPKVPDPEDEKPTMGLKWVRLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
KMPVAYLLVGVVLLGAIAIPATNMRLAMPTDGTSTLGTAPRTAYDMTADAFGPGRNAPMI
HCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCHHCCCCCCCCCEE
ALIDATDVPEEERPLVFGQAVEQFLNTDGVKNAQITQTTENFDTAQILITPEFDAIDERT
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCHHHHHHH
SETLATLRADAETFADDTGATYGITGVTPIYDDISARLGDVLVPYVLIVLVLAFLVLLLV
HHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSIWVPLIAALGFGLSVLATFGATVAIFQEGAFGIIDDPQPLLSFLPIMLIGLVFGLAM
HHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DYQIFLVTRMREGFTKGKTAGNATSNGFKHGARVVTAAALIMVSVFAAFIAQDMAFIKTM
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFALAVAVFFDAFVVRMMIIPATMFLLDDKAWWLPKWLDKILPNVDVEGEGLSELHEART
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
EELKENVGVGA
HHHHHHCCCCC
>Mature Secondary Structure 
AKFLYKLGSTAYQKKWPFLAVWLVILIGITTLAGLYAKPTSSSFSIPGLDSVTTMEKMQ
HHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ERFPGSDDATSAPTGSVVIQAPEGKTLTDPEVGAEVNQMLDEVRATGVLKDADSVVDPVL
HHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
AAQGVAAQMTPALEAQGVPAEKIAADIESISPLSADETTGIISMTFDADSAMDISAEDRE
HHCCCHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHH
KVTNILDEYDDGDLTVVYNGNVFGAAATSLDMTSELIGLLVAAVVLIVTFGSFIAAGMPL
HHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAIIGVGIGIMGIQLATAFTDSVNDMTPTLASMIGLAVGIDYALFIVSRFRNELISQTG
HHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANDLEPKELAERLRTMPLAARAHAMGMAVGTAGSAVVFAGTTVLIALVALSIINIPFLTV
CCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
MAIAAAITVAIAVLVALSFLPALLGLLGTRIFAARVPGPKVPDPEDEKPTMGLKWVRLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
KMPVAYLLVGVVLLGAIAIPATNMRLAMPTDGTSTLGTAPRTAYDMTADAFGPGRNAPMI
HCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHCCHHCCCCCCCCCEE
ALIDATDVPEEERPLVFGQAVEQFLNTDGVKNAQITQTTENFDTAQILITPEFDAIDERT
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCHHHHHHH
SETLATLRADAETFADDTGATYGITGVTPIYDDISARLGDVLVPYVLIVLVLAFLVLLLV
HHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSIWVPLIAALGFGLSVLATFGATVAIFQEGAFGIIDDPQPLLSFLPIMLIGLVFGLAM
HHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DYQIFLVTRMREGFTKGKTAGNATSNGFKHGARVVTAAALIMVSVFAAFIAQDMAFIKTM
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFALAVAVFFDAFVVRMMIIPATMFLLDDKAWWLPKWLDKILPNVDVEGEGLSELHEART
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
EELKENVGVGA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]