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The map label for this gene is yabD [H]

Identifier: 62389798

GI number: 62389798

Start: 964279

End: 965112

Strand: Direct

Name: yabD [H]

Synonym: cg1035

Alternate gene names: 62389798

Gene position: 964279-965112 (Clockwise)

Preceding gene: 62389797

Following gene: 62389799

Centisome position: 29.37

GC content: 53.84

Gene sequence:

>834_bases
ATGTCTAAGAAGAAGCCTCGCCCCATTCCGGTTCCTGCCCAATTTATCCCTGGTCTCATTGATGCGCATACACATTTGGC
ATCGTGTGGAGGAGATCTTGCAGGGTTGGTGGAAAGGGCCAAGGAGGCGGGCGTCGAAAAGCTTTGTACCGTCGGTGATG
GTTTGGCTGAGGCCGAGCTTGCGCTGGAGGCCGCGCAACAGTTTGGCAATGTGTTTGCTGCGTGTGCGATTCATCCGACG
AAGGCTGATCAGTTGGATGGGGCTGCGCGTGCGCGGCTGACGCAGATGGCGGCGGATCCGAATTGTGTGGCCATTGGTGA
GACTGGTTTGGATTCGTATTGGATCAAGCACGATCCAGAGGACACGGCGGCGTTGGATGTGCAAGAGGAGGCGCTGCGCT
GGCATATTGATTTGGCAATTAGTGCGGATAAGCCGTTGATGATTCACAATCGTGAGGCGGATGCTGATTTGATGCGAGTG
TTGGCGGATGCTCCACCTCCAAAAGATACGATTCTGCATTGTTTTTCTTCGCCGTTGGACGTGGCGAAGGAAGCGTTGGA
TCGTGGATATGTGTTGAGTTTTGCGGGCAATGTGACGTTTAAGCGTAATGAGGAGTTGCGGGAGGCTGCTCGTATTGCGC
CGATTTCCCAGATTTTGATTGAAACCGATGCGCCGTATATGACGCCGGAGCCGTTTCGGGGGAGTAGGAATGAGCCGTCG
TTGATTGGTCATACGGCGCTATGCATTGCGGAGGTTCGGGGGATGGCTGTGGAGGATGTTGCGGCGGCTTTGAATGAGAA
TTTTGATCGCGTTTATGGGGTCACAAATCTATAA

Upstream 100 bases:

>100_bases
AGGTCTTGTTTATTTCGGCTACTGATTCAGTAGCTGCGCTCCGATAGGATTCTTAGTTTTCAGTTCAGTATCTTTGAGCC
ACGGCTAGAATGTGAATCCT

Downstream 100 bases:

>100_bases
CGTGAGGTAGCTCACAGTCAATCTGTTGGCCGTGGTCAGCTGTGGGGGTTGTGGTGGGTGTGACTGAAGTTTATGAAGTT
GCACGCCACGGCGTTTTGGT

Product: TatD related DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSKKKPRPIPVPAQFIPGLIDAHTHLASCGGDLAGLVERAKEAGVEKLCTVGDGLAEAELALEAAQQFGNVFAACAIHPT
KADQLDGAARARLTQMAADPNCVAIGETGLDSYWIKHDPEDTAALDVQEEALRWHIDLAISADKPLMIHNREADADLMRV
LADAPPPKDTILHCFSSPLDVAKEALDRGYVLSFAGNVTFKRNEELREAARIAPISQILIETDAPYMTPEPFRGSRNEPS
LIGHTALCIAEVRGMAVEDVAAALNENFDRVYGVTNL

Sequences:

>Translated_277_residues
MSKKKPRPIPVPAQFIPGLIDAHTHLASCGGDLAGLVERAKEAGVEKLCTVGDGLAEAELALEAAQQFGNVFAACAIHPT
KADQLDGAARARLTQMAADPNCVAIGETGLDSYWIKHDPEDTAALDVQEEALRWHIDLAISADKPLMIHNREADADLMRV
LADAPPPKDTILHCFSSPLDVAKEALDRGYVLSFAGNVTFKRNEELREAARIAPISQILIETDAPYMTPEPFRGSRNEPS
LIGHTALCIAEVRGMAVEDVAAALNENFDRVYGVTNL
>Mature_276_residues
SKKKPRPIPVPAQFIPGLIDAHTHLASCGGDLAGLVERAKEAGVEKLCTVGDGLAEAELALEAAQQFGNVFAACAIHPTK
ADQLDGAARARLTQMAADPNCVAIGETGLDSYWIKHDPEDTAALDVQEEALRWHIDLAISADKPLMIHNREADADLMRVL
ADAPPPKDTILHCFSSPLDVAKEALDRGYVLSFAGNVTFKRNEELREAARIAPISQILIETDAPYMTPEPFRGSRNEPSL
IGHTALCIAEVRGMAVEDVAAALNENFDRVYGVTNL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=28.2527881040892, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI226061853, Length=277, Percent_Identity=27.7978339350181, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226061614, Length=262, Percent_Identity=26.7175572519084, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI14042943, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=33.206106870229, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI48994985, Length=248, Percent_Identity=31.4516129032258, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082439, Length=260, Percent_Identity=26.9230769230769, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=27.8169014084507, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=26.3358778625954, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565396, Length=193, Percent_Identity=30.5699481865285, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648690, Length=208, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586117, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221330018, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29839; Mature: 29708

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKKPRPIPVPAQFIPGLIDAHTHLASCGGDLAGLVERAKEAGVEKLCTVGDGLAEAEL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHCCCHHHHHH
ALEAAQQFGNVFAACAIHPTKADQLDGAARARLTQMAADPNCVAIGETGLDSYWIKHDPE
HHHHHHHHHHHHHHEEECCCCCHHCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCC
DTAALDVQEEALRWHIDLAISADKPLMIHNREADADLMRVLADAPPPKDTILHCFSSPLD
CHHHHHHHHHHHEEEEEEEEECCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCHHH
VAKEALDRGYVLSFAGNVTFKRNEELREAARIAPISQILIETDAPYMTPEPFRGSRNEPS
HHHHHHCCCEEEEEECCEEECCCHHHHHHHHHCHHHHHHEECCCCCCCCCCCCCCCCCCC
LIGHTALCIAEVRGMAVEDVAAALNENFDRVYGVTNL
HHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCC
>Mature Secondary Structure 
SKKKPRPIPVPAQFIPGLIDAHTHLASCGGDLAGLVERAKEAGVEKLCTVGDGLAEAEL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHCCCHHHHHH
ALEAAQQFGNVFAACAIHPTKADQLDGAARARLTQMAADPNCVAIGETGLDSYWIKHDPE
HHHHHHHHHHHHHHEEECCCCCHHCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCC
DTAALDVQEEALRWHIDLAISADKPLMIHNREADADLMRVLADAPPPKDTILHCFSSPLD
CHHHHHHHHHHHEEEEEEEEECCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCHHH
VAKEALDRGYVLSFAGNVTFKRNEELREAARIAPISQILIETDAPYMTPEPFRGSRNEPS
HHHHHHCCCEEEEEECCEEECCCHHHHHHHHHCHHHHHHEECCCCCCCCCCCCCCCCCCC
LIGHTALCIAEVRGMAVEDVAAALNENFDRVYGVTNL
HHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]