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The map label for this gene is ygfA [C]

Identifier: 62389770

GI number: 62389770

Start: 935199

End: 935771

Strand: Reverse

Name: ygfA [C]

Synonym: cg1003

Alternate gene names: 62389770

Gene position: 935771-935199 (Counterclockwise)

Preceding gene: 62389779

Following gene: 62389769

Centisome position: 28.51

GC content: 55.85

Gene sequence:

>573_bases
ATGAGCCAAACTAAGCAGGAACTGCGCACGAAGCTTCGGGAAGCGCGCACCAATATGGATGAGGCTTCTCGCACGCGAGA
AAACGCAGCCATCATTGCCAACGTTTCTTATTACATCCGCTCAAAGCAGCCAAAAAGGATTGCCGCTTACGTGCCGGTGC
GTACCGAACCTGGTGGGCGATTGCTTCTCGACGCCCTCCACGCCGAAACTTCCGCGCTTATTTTGCCAGTCTCCCTCGAG
GATCGACGCCTCGACTGGGCTCTTTATGAAGGCCCAACCAGCCTTGTTCCTGGCGCATTTGGCATCCAGGAACCCGGTGG
CACTCGCCTTGGACCTGAAGCTCTCAACTTCTGCGACCTTGTCATCGCCCCCGCACTGGCATGCACCCCCAGTGGAATCA
GGCTAGGTAAAGGTGGCGGTTTCTACGACCGCGCTCTAGCCACCGGAGTCAAGGCTGACGTGATTACTTTGCTCTTCAAC
GGAGAAATCCGCGACGATATCGAAGTGGAAGAACATGATCTTCCCGTCAACGTCATAATTACCCCCGCAGGTGTTCGGAA
CCTAGGAGCCTAA

Upstream 100 bases:

>100_bases
TCACGTGCTCATCGATAGGCAAACTCATGGAACCAAGAGTACCTGCCCCCGCAACCCCAATCGTCGTACCCCTCCGAAAA
TAACGGTTATCCTTAGATTT

Downstream 100 bases:

>100_bases
AAAACAGTCCAACCACTATATGGACTTAAAAAAGACATTCACCACCCCGAGTTGGCACCGCACCCTAGTTTTAAGAAGAA
TAATCGCCTTCATCCTGATC

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSQTKQELRTKLREARTNMDEASRTRENAAIIANVSYYIRSKQPKRIAAYVPVRTEPGGRLLLDALHAETSALILPVSLE
DRRLDWALYEGPTSLVPGAFGIQEPGGTRLGPEALNFCDLVIAPALACTPSGIRLGKGGGFYDRALATGVKADVITLLFN
GEIRDDIEVEEHDLPVNVIITPAGVRNLGA

Sequences:

>Translated_190_residues
MSQTKQELRTKLREARTNMDEASRTRENAAIIANVSYYIRSKQPKRIAAYVPVRTEPGGRLLLDALHAETSALILPVSLE
DRRLDWALYEGPTSLVPGAFGIQEPGGTRLGPEALNFCDLVIAPALACTPSGIRLGKGGGFYDRALATGVKADVITLLFN
GEIRDDIEVEEHDLPVNVIITPAGVRNLGA
>Mature_189_residues
SQTKQELRTKLREARTNMDEASRTRENAAIIANVSYYIRSKQPKRIAAYVPVRTEPGGRLLLDALHAETSALILPVSLED
RRLDWALYEGPTSLVPGAFGIQEPGGTRLGPEALNFCDLVIAPALACTPSGIRLGKGGGFYDRALATGVKADVITLLFNG
EIRDDIEVEEHDLPVNVIITPAGVRNLGA

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 20578; Mature: 20447

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTKQELRTKLREARTNMDEASRTRENAAIIANVSYYIRSKQPKRIAAYVPVRTEPGGR
CCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEEEEEECCCCE
LLLDALHAETSALILPVSLEDRRLDWALYEGPTSLVPGAFGIQEPGGTRLGPEALNFCDL
EEHEEHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VIAPALACTPSGIRLGKGGGFYDRALATGVKADVITLLFNGEIRDDIEVEEHDLPVNVII
HHHHHHHCCCCCEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCCCCEEEEE
TPAGVRNLGA
CCCCCCCCCC
>Mature Secondary Structure 
SQTKQELRTKLREARTNMDEASRTRENAAIIANVSYYIRSKQPKRIAAYVPVRTEPGGR
CHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEEEEEECCCCE
LLLDALHAETSALILPVSLEDRRLDWALYEGPTSLVPGAFGIQEPGGTRLGPEALNFCDL
EEHEEHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
VIAPALACTPSGIRLGKGGGFYDRALATGVKADVITLLFNGEIRDDIEVEEHDLPVNVII
HHHHHHHCCCCCEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCCCCEEEEE
TPAGVRNLGA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]