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The map label for this gene is sigH [H]

Identifier: 62389655

GI number: 62389655

Start: 805881

End: 806501

Strand: Direct

Name: sigH [H]

Synonym: cg0876

Alternate gene names: 62389655

Gene position: 805881-806501 (Clockwise)

Preceding gene: 62389653

Following gene: 62389656

Centisome position: 24.55

GC content: 50.89

Gene sequence:

>621_bases
ATGGCTGAAAACCGAACCGGCACAGTCGATGGAGACGCGTTGGCTGCCCGCTTTGAAGAGGAGGCACTGCCACTCCTTGA
CCAGCTCTATGGCGGTGCTCTGCGCATGACTAGAAATCCCGCAGATGCGGAAGATCTCGTGCAAGACACCTATATCAAGG
CGTACCAGGCGTTCGCGAGCTTCAAACCAGGCACCAACCTGAAGGCTTGGCTCTATCGGATCATGACGAATACCTACATC
AACATGTACCGAAAGAAACAGAGGCAGCCATCGCAAACCTCTGCCGATGAGATCACTGACTACCAGCTCGTTGAATCTCA
ATCGCATACCTCAACAGGGCTGGAATCCGCCGAGGTTGAGGCTCTGAAAAATCTGCCAGACGGAAAAATTGGCGATGCAA
TGAATCAACTCAGCCCGGAATACCGGATGGTGGTTTATTATGCCGATGTAGAAGATCTCGCATACAAAGAAATCGCCGAG
ATCATGGACGTTCCACTCGGAACTGTGATGTCCCGACTCCATCGTGGAAGAAAACAGCTCCGAGGAATGTTAAAGGAAGT
AGCGAAGGAACAAGGCATTGGTCTTGAACATCCCGACATGAAGAAAAATTCGGAGGCATAA

Upstream 100 bases:

>100_bases
AAAGTCTAAGCAACAGCTCACGTGGCTTTACAGCTACCCCCGAAAGGTCTGTTTTTTATCGGAAGTAGAATAGTCAACAC
GCATTTTCGAAAGGGGCCAC

Downstream 100 bases:

>100_bases
CGATGACGAATCTCAACCGCAGCGACTCGCAAGGTGATTGTGGCTGCCCTGAATTCTTCGATGAAATGTATCAGCTACTC
GACGATCAACTCAGCGAGTC

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MAENRTGTVDGDALAARFEEEALPLLDQLYGGALRMTRNPADAEDLVQDTYIKAYQAFASFKPGTNLKAWLYRIMTNTYI
NMYRKKQRQPSQTSADEITDYQLVESQSHTSTGLESAEVEALKNLPDGKIGDAMNQLSPEYRMVVYYADVEDLAYKEIAE
IMDVPLGTVMSRLHRGRKQLRGMLKEVAKEQGIGLEHPDMKKNSEA

Sequences:

>Translated_206_residues
MAENRTGTVDGDALAARFEEEALPLLDQLYGGALRMTRNPADAEDLVQDTYIKAYQAFASFKPGTNLKAWLYRIMTNTYI
NMYRKKQRQPSQTSADEITDYQLVESQSHTSTGLESAEVEALKNLPDGKIGDAMNQLSPEYRMVVYYADVEDLAYKEIAE
IMDVPLGTVMSRLHRGRKQLRGMLKEVAKEQGIGLEHPDMKKNSEA
>Mature_205_residues
AENRTGTVDGDALAARFEEEALPLLDQLYGGALRMTRNPADAEDLVQDTYIKAYQAFASFKPGTNLKAWLYRIMTNTYIN
MYRKKQRQPSQTSADEITDYQLVESQSHTSTGLESAEVEALKNLPDGKIGDAMNQLSPEYRMVVYYADVEDLAYKEIAEI
MDVPLGTVMSRLHRGRKQLRGMLKEVAKEQGIGLEHPDMKKNSEA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=144, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23218; Mature: 23086

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENRTGTVDGDALAARFEEEALPLLDQLYGGALRMTRNPADAEDLVQDTYIKAYQAFAS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
FKPGTNLKAWLYRIMTNTYINMYRKKQRQPSQTSADEITDYQLVESQSHTSTGLESAEVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHH
ALKNLPDGKIGDAMNQLSPEYRMVVYYADVEDLAYKEIAEIMDVPLGTVMSRLHRGRKQL
HHHCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RGMLKEVAKEQGIGLEHPDMKKNSEA
HHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AENRTGTVDGDALAARFEEEALPLLDQLYGGALRMTRNPADAEDLVQDTYIKAYQAFAS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
FKPGTNLKAWLYRIMTNTYINMYRKKQRQPSQTSADEITDYQLVESQSHTSTGLESAEVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHH
ALKNLPDGKIGDAMNQLSPEYRMVVYYADVEDLAYKEIAEIMDVPLGTVMSRLHRGRKQL
HHHCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RGMLKEVAKEQGIGLEHPDMKKNSEA
HHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]