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The map label for this gene is aroA [H]

Identifier: 62389652

GI number: 62389652

Start: 802660

End: 803952

Strand: Reverse

Name: aroA [H]

Synonym: cg0873

Alternate gene names: 62389652

Gene position: 803952-802660 (Counterclockwise)

Preceding gene: 62389654

Following gene: 62389651

Centisome position: 24.49

GC content: 53.13

Gene sequence:

>1293_bases
ATGGTCTTTGTGTCTGATTCGTCTATCTCTTTGCCCATTTGGGATGCTCCGCGCGCTCGCGGCCCCATAGTCTCGGACCT
GGCTATCCCTGGTTCCAAGTCGATCACCAACCGCGCCCTCATCTTGGCTGCGCTCGCATCAACTCCATCCACCATCATTG
ATGTCCTTCGTAGTCGTGATACCGATCTCATGACTGATGGTCTACGCAGCCTCGGAATCACCATTACTGAAGAGGCAGTC
GATCGCTACCGCGTTGAGCCCGGACAGTTGTCTGCTGGCTCCGTTGAGTGTGGTCTTGCTGGTACGGTCATGCGCTTTTT
GCCTCCTGTTGCTGCTTTCGCTGATGGTCCTGTTCATTTTGATGGCGATCCTCAAGCTCGTGTTCGTCCGATGACCAGCA
TTTTGGATGCGCTGCGTTCGCTTGGTGTGGAGGTAGACAACAACAATCTGCCTTTCACTGTTAATGCTGGTGAGGTCCCT
GAGGGTGGCGTGGTTGAGATTGATGCTTCCGGCTCATCTCAGTTTGTTTCTGGTCTTTTGCTTTCAGCGCCTCGTTTTAA
AAATGGCGTCACCGTTAAGCACGTCGGTGGTCGTCTGCCGAGCATGCCGCATATTGAGATGACCGTCGATATGCTTCGTT
CCGCAGGCATTGAGATCGAAGAGTCAGAAAATCAGTGGGTTGTTCATCCTGGTGAGATCTTGGGTCGGACCTGGCGCATT
GAGCCGGATCTTTCTAATGCGACTCCGTTCCTAGCTGCCGCTGCGGTCACTGGTGGAACCATCAAGATTAACCACTGGCC
AATCAAAACTACTCAGCCTGGCGATGCTATTCGTTCGATTCTTGAGCGCATGGGCTGCGAAGTTGAGCTGGTTGCTCAGG
GTGAAGGTTACGATCTGTCGGTGACTGGTCCGGTTGCTCTCAAGGGCATTGAGATCGATATGTCCGATATCGGTGAGTTG
ACCCCTACCGTGGCGGCGTTGGCTGCGTTGGCGTCGACAGAGTCTCGTTTGACCGGTATTGCTCATCTTCGTGGCCATGA
GACGGATCGTTTGGCTGCGTTGACTGCGGAGATCAACAAACTTGGTGGAAAGTGCACTGAGCTTAAGGATGGTCTGTTGA
TTGAGCCTGCGTCGCTGCACGGTGGTGTGTGGCATTCATATGCTGATCACCGTATGGCTACTGCTGGTGCGATCATTGGC
CTCGCGGTTGATGGCGTTCAGGTTGAAGACATTAAGACCACTTCCAAAACTTTCCCTGGTTTTGAAAATGTTTGGGAGGA
GATGGTTGGCTAG

Upstream 100 bases:

>100_bases
TTGCGGAGCCACGACTGATCGGTCAAGTGCTATCTCGGTTGCATCAATAAGCGAATCACCGGTGGTGAACAAAACAAATC
TTCCACACATAACATCTATT

Downstream 100 bases:

>100_bases
ACGCAGCTATGACGAATCCGATGTTCGTGTTCGCCCAGGTAAAGGTACCCGCCCTCGTACGAAGGATCGGCCATCGCATG
AGAATGCTCTAGTGGGCATG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRDTDLMTDGLRSLGITITEEAV
DRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHFDGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVP
EGGVVEIDASGSSQFVSGLLLSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLSVTGPVALKGIEIDMSDIGEL
TPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINKLGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIG
LAVDGVQVEDIKTTSKTFPGFENVWEEMVG

Sequences:

>Translated_430_residues
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRDTDLMTDGLRSLGITITEEAV
DRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHFDGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVP
EGGVVEIDASGSSQFVSGLLLSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLSVTGPVALKGIEIDMSDIGEL
TPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINKLGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIG
LAVDGVQVEDIKTTSKTFPGFENVWEEMVG
>Mature_430_residues
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRDTDLMTDGLRSLGITITEEAV
DRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHFDGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVP
EGGVVEIDASGSSQFVSGLLLSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLSVTGPVALKGIEIDMSDIGEL
TPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINKLGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIG
LAVDGVQVEDIKTTSKTFPGFENVWEEMVG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=410, Percent_Identity=35.1219512195122, Blast_Score=182, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6320332, Length=480, Percent_Identity=31.25, Blast_Score=165, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45528; Mature: 45528

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRD
CEEECCCCEEEEECCCCCCCCCCEEHEECCCCCCHHHHHEEEEEHHCCHHHHHHHHHCCC
TDLMTDGLRSLGITITEEAVDRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHF
CHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEE
DGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVPEGGVVEIDASGSSQFVSGLL
CCCCCHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHH
LSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
HCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCEEEE
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLS
CCCCCCCCCHHEEHEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEE
VTGPVALKGIEIDMSDIGELTPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINK
EECCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIGLAVDGVQVEDIKTTSKTFPG
HCCCHHHCCCCEEEECHHCCCCHHHHHHHHHHHHHCEEEEEEECCEEEECCCCCCCCCCC
FENVWEEMVG
HHHHHHHHCC
>Mature Secondary Structure
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRD
CEEECCCCEEEEECCCCCCCCCCEEHEECCCCCCHHHHHEEEEEHHCCHHHHHHHHHCCC
TDLMTDGLRSLGITITEEAVDRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHF
CHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEE
DGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVPEGGVVEIDASGSSQFVSGLL
CCCCCHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHH
LSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
HCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCEEEE
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLS
CCCCCCCCCHHEEHEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEE
VTGPVALKGIEIDMSDIGELTPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINK
EECCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIGLAVDGVQVEDIKTTSKTFPG
HCCCHHHCCCCEEEECHHCCCCHHHHHHHHHHHHHCEEEEEEECCEEEECCCCCCCCCCC
FENVWEEMVG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA