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The map label for this gene is fabG [H]

Identifier: 62389608

GI number: 62389608

Start: 741698

End: 742489

Strand: Reverse

Name: fabG [H]

Synonym: cg0825

Alternate gene names: 62389608

Gene position: 742489-741698 (Counterclockwise)

Preceding gene: 62389610

Following gene: 62389607

Centisome position: 22.62

GC content: 57.7

Gene sequence:

>792_bases
ATGCTTGATATTTCTGAGCAAATTGTTTTGGTCACCGGCGGTGCACGCGGACTTGGTCGCGCGTTGTCTGAATCATTTTT
GCGCGAGGGTGCTCGTGTTGTGGTGAACTATCACCGTTCGGCTGATGCTGCCGCAGAGCTGGCTGGTGAAAAGGCGGTGG
CGATTCAGGCTGATGTTCGTGATCGCGAACAGGTGAAAAGCATGTTTGCGCAGGCCAAGGAACATTTCGGCAGCCCGATC
ACCACTGTGGTCAACAGCGCTTTGGCGGATTTCAGCTTTGATGGCGATGCGCGTCCCAAGGCGGAGGACATCACCATTGA
GCGTTTTAATCAGCAGTACACCAGCGCAATCGAGGGCGCGCTGAACACCATCCAGGAGGCTTTGCCTGGTTTTGAGGAGG
TGGGAAGTGGTCGTGTGATTAACATCGGCACGAATCTTTTCCAGAATCCGACTGTCCCCTACCACGATTACACCGCTGCG
AAGGCTGCGCTGCTGTCCTTGACTCGCACGTTTGCCAAGGATTTGGGCCCACGCCACATCACGGTCAACATGGTCAGCGG
CGGCCTGCTGCGCACCACCGGCGCCAGCGCCGCCACGCCCGAGGAAGTCTTTGATTTCATCGCCGCCGGCACCCCACTGG
GGTCCGTCACCACTCCCCAAGAGCTTGCCGACGCCTCCCTCTTCTTCGCATCCCCCTGGTCGCGCGCGGTTACAGGCCAA
AACTTGGTCGTCGACGGAGGACTGGTTTTCAACTGTTTTGTGTCAGAGGGTTGTGCACACTCAGTGTCATGA

Upstream 100 bases:

>100_bases
GATCCAGTTAGTACTGGCGAAGGGACTGTCGCATTGGACCCATCCTCCCAAGGGATAGGTCCCTCTGCCCTTCGCCCCAA
CCCAAGAAGGGCGTTTTTTC

Downstream 100 bases:

>100_bases
CCTTATGCACACTTAATGCCATGACCTTGTGCATGCATAGTGTCATGACCTTGTGCACACCCCAGACCTACACCACAGGC
ATAGTCCTAGGCTGCTCACA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLDISEQIVLVTGGARGLGRALSESFLREGARVVVNYHRSADAAAELAGEKAVAIQADVRDREQVKSMFAQAKEHFGSPI
TTVVNSALADFSFDGDARPKAEDITIERFNQQYTSAIEGALNTIQEALPGFEEVGSGRVINIGTNLFQNPTVPYHDYTAA
KAALLSLTRTFAKDLGPRHITVNMVSGGLLRTTGASAATPEEVFDFIAAGTPLGSVTTPQELADASLFFASPWSRAVTGQ
NLVVDGGLVFNCFVSEGCAHSVS

Sequences:

>Translated_263_residues
MLDISEQIVLVTGGARGLGRALSESFLREGARVVVNYHRSADAAAELAGEKAVAIQADVRDREQVKSMFAQAKEHFGSPI
TTVVNSALADFSFDGDARPKAEDITIERFNQQYTSAIEGALNTIQEALPGFEEVGSGRVINIGTNLFQNPTVPYHDYTAA
KAALLSLTRTFAKDLGPRHITVNMVSGGLLRTTGASAATPEEVFDFIAAGTPLGSVTTPQELADASLFFASPWSRAVTGQ
NLVVDGGLVFNCFVSEGCAHSVS
>Mature_263_residues
MLDISEQIVLVTGGARGLGRALSESFLREGARVVVNYHRSADAAAELAGEKAVAIQADVRDREQVKSMFAQAKEHFGSPI
TTVVNSALADFSFDGDARPKAEDITIERFNQQYTSAIEGALNTIQEALPGFEEVGSGRVINIGTNLFQNPTVPYHDYTAA
KAALLSLTRTFAKDLGPRHITVNMVSGGLLRTTGASAATPEEVFDFIAAGTPLGSVTTPQELADASLFFASPWSRAVTGQ
NLVVDGGLVFNCFVSEGCAHSVS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=28.4046692607004, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=29.1338582677165, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=24.4094488188976, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=27.3092369477912, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.3814432989691, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=27.3469387755102, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI59889578, Length=244, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=31.7460317460317, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=26.4822134387352, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=29.7520661157025, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082100, Length=274, Percent_Identity=27.007299270073, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=28, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=28, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=24.2063492063492, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=25.296442687747, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=29.1338582677165, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=28.8537549407115, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=25.0922509225092, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=27.9411764705882, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=25.7246376811594, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.1698113207547, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=214, Percent_Identity=28.9719626168224, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=27.9850746268657, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.8195488721804, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=25.9541984732824, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=27.1317829457364, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=27.3408239700375, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=26.7716535433071, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=28.7449392712551, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17737361, Length=265, Percent_Identity=28.3018867924528, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=28.4, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=22.4409448818898, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=25.1968503937008, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 27867; Mature: 27867

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDISEQIVLVTGGARGLGRALSESFLREGARVVVNYHRSADAAAELAGEKAVAIQADVR
CCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEEECCCC
DREQVKSMFAQAKEHFGSPITTVVNSALADFSFDGDARPKAEDITIERFNQQYTSAIEGA
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LNTIQEALPGFEEVGSGRVINIGTNLFQNPTVPYHDYTAAKAALLSLTRTFAKDLGPRHI
HHHHHHHCCCHHHHCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
TVNMVSGGLLRTTGASAATPEEVFDFIAAGTPLGSVTTPQELADASLFFASPWSRAVTGQ
EEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEECCCHHHCCCC
NLVVDGGLVFNCFVSEGCAHSVS
EEEEECCEEEEEEHHCCCCCCCC
>Mature Secondary Structure
MLDISEQIVLVTGGARGLGRALSESFLREGARVVVNYHRSADAAAELAGEKAVAIQADVR
CCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEEECCCC
DREQVKSMFAQAKEHFGSPITTVVNSALADFSFDGDARPKAEDITIERFNQQYTSAIEGA
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LNTIQEALPGFEEVGSGRVINIGTNLFQNPTVPYHDYTAAKAALLSLTRTFAKDLGPRHI
HHHHHHHCCCHHHHCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
TVNMVSGGLLRTTGASAATPEEVFDFIAAGTPLGSVTTPQELADASLFFASPWSRAVTGQ
EEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEECCCHHHCCCC
NLVVDGGLVFNCFVSEGCAHSVS
EEEEECCEEEEEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA