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The map label for this gene is alr [H]

Identifier: 62389477

GI number: 62389477

Start: 600972

End: 602057

Strand: Direct

Name: alr [H]

Synonym: cg0681

Alternate gene names: 62389477

Gene position: 600972-602057 (Clockwise)

Preceding gene: 62389475

Following gene: 62389478

Centisome position: 18.31

GC content: 55.62

Gene sequence:

>1086_bases
ATGAACTTGCTGACCACCAAAATTGACCTGGATGCCATCGCCCATAACACGAGGGTGCTTAAACAAATGGCGGGTCCGGC
GAAGCTGATGGCGGTGGTGAAGGCGAATGCATATAACCATGGCGTAGAGAAGGTCGCTCCGGTTATTGCTGCTCATGGTG
CGGATGCGTTTGGTGTGGCAACTCTTGCGGAGGCTATGCAGTTGCGTGATATCGGCATCAGCCAAGAGGTTTTGTGTTGG
ATTTGGACACCGGAGCAGGATTTCCGCGCCGCCATTGATCGCAATATTGATTTGGCTGTTATTTCTCCCGCGCATGCCAA
AGCCTTGATCGAAACTGATGCGGAGCATATTCGGGTGTCCATCAAGATTGATTCTGGGTTGCATCGTTCGGGTGTGGATG
AGCAGGAGTGGGAGGGCGTGTTCAGCGCGTTGGCTGCTGCCCCGCACATTGAGGTCACGGGCATGTTCACGCACTTGGCG
TGCGCGGATGAGCCAGAGAATCCGGAAACTGATCGCCAAATTATTGCTTTTCGACGCGCCCTTGCGCTCGCCCGCAAGCA
CGGGCTTGAGTGCCCGGTCAACCACGTATGCAACTCACCTGCATTCTTGACTCGATCTGATTTACACATGGAGATGGTCC
GACCGGGTTTGGCCTTTTATGGGTTGGAACCCGTGGCGGGACTGGAGCATGGTTTGAAGCCGGCGATGACGTGGGAGGCG
AAGGTGAGCGTCGTAAAGCAAATTGAAGCTGGACAAGGCACTTCCTATGGCCTGACCTGGCGCGCTGAGGATCGCGGCTT
TGTGGCTGTGGTGCCTGCGGGCTATGCCGATGGCATGCCGCGGCATGCCCAGGGGAAATTCTCCGTCACGATTGATGGCC
TGGACTATCCGCAGGTTGGGCGCGTATGCATGGATCAGTTCGTTATTTCTTTGGGCGACAATCCACACGGCGTGGAAGCT
GGGGCGAAGGCCGTGATATTCGGTGAGAATGGGCATGACGCAACTGATTTTGCGGAGCGTTTAGACACCATTAACTATGA
GGTAGTGTGCCGACCAACCGGCCGAACTGTCCGCGCATATGTTTAA

Upstream 100 bases:

>100_bases
AGCCACGTGTTTAAGGATAGTTGAAAGCGTGGGGCAATACTGGCACTAACCCCGGCACCAATCGTATTTCTGTCCGCGGT
TGGTGGCACAATAGTTCAAC

Downstream 100 bases:

>100_bases
GTGAATACGTTTAAGGAGCAGCAATGAAATCTGAGTTTCCGGTATCCGGCACGAGGCGTTTTGAGCATGCCGCAGATACC
CAAAATTTTGGGGAAGAATT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MNLLTTKIDLDAIAHNTRVLKQMAGPAKLMAVVKANAYNHGVEKVAPVIAAHGADAFGVATLAEAMQLRDIGISQEVLCW
IWTPEQDFRAAIDRNIDLAVISPAHAKALIETDAEHIRVSIKIDSGLHRSGVDEQEWEGVFSALAAAPHIEVTGMFTHLA
CADEPENPETDRQIIAFRRALALARKHGLECPVNHVCNSPAFLTRSDLHMEMVRPGLAFYGLEPVAGLEHGLKPAMTWEA
KVSVVKQIEAGQGTSYGLTWRAEDRGFVAVVPAGYADGMPRHAQGKFSVTIDGLDYPQVGRVCMDQFVISLGDNPHGVEA
GAKAVIFGENGHDATDFAERLDTINYEVVCRPTGRTVRAYV

Sequences:

>Translated_361_residues
MNLLTTKIDLDAIAHNTRVLKQMAGPAKLMAVVKANAYNHGVEKVAPVIAAHGADAFGVATLAEAMQLRDIGISQEVLCW
IWTPEQDFRAAIDRNIDLAVISPAHAKALIETDAEHIRVSIKIDSGLHRSGVDEQEWEGVFSALAAAPHIEVTGMFTHLA
CADEPENPETDRQIIAFRRALALARKHGLECPVNHVCNSPAFLTRSDLHMEMVRPGLAFYGLEPVAGLEHGLKPAMTWEA
KVSVVKQIEAGQGTSYGLTWRAEDRGFVAVVPAGYADGMPRHAQGKFSVTIDGLDYPQVGRVCMDQFVISLGDNPHGVEA
GAKAVIFGENGHDATDFAERLDTINYEVVCRPTGRTVRAYV
>Mature_361_residues
MNLLTTKIDLDAIAHNTRVLKQMAGPAKLMAVVKANAYNHGVEKVAPVIAAHGADAFGVATLAEAMQLRDIGISQEVLCW
IWTPEQDFRAAIDRNIDLAVISPAHAKALIETDAEHIRVSIKIDSGLHRSGVDEQEWEGVFSALAAAPHIEVTGMFTHLA
CADEPENPETDRQIIAFRRALALARKHGLECPVNHVCNSPAFLTRSDLHMEMVRPGLAFYGLEPVAGLEHGLKPAMTWEA
KVSVVKQIEAGQGTSYGLTWRAEDRGFVAVVPAGYADGMPRHAQGKFSVTIDGLDYPQVGRVCMDQFVISLGDNPHGVEA
GAKAVIFGENGHDATDFAERLDTINYEVVCRPTGRTVRAYV

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=368, Percent_Identity=32.6086956521739, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=30.028328611898, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39174; Mature: 39174

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLTTKIDLDAIAHNTRVLKQMAGPAKLMAVVKANAYNHGVEKVAPVIAAHGADAFGVA
CCEEEEEEEHHHHHHHHHHHHHHCCHHHEEHHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
TLAEAMQLRDIGISQEVLCWIWTPEQDFRAAIDRNIDLAVISPAHAKALIETDAEHIRVS
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEEEEE
IKIDSGLHRSGVDEQEWEGVFSALAAAPHIEVTGMFTHLACADEPENPETDRQIIAFRRA
EEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHH
LALARKHGLECPVNHVCNSPAFLTRSDLHMEMVRPGLAFYGLEPVAGLEHGLKPAMTWEA
HHHHHHCCCCCCHHHHCCCCCEEECCCCHHHHHCCCCEEECCCCHHHHHHCCCCCEEHHH
KVSVVKQIEAGQGTSYGLTWRAEDRGFVAVVPAGYADGMPRHAQGKFSVTIDGLDYPQVG
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHH
RVCMDQFVISLGDNPHGVEAGAKAVIFGENGHDATDFAERLDTINYEVVCRPTGRTVRAY
HHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEE
V
C
>Mature Secondary Structure
MNLLTTKIDLDAIAHNTRVLKQMAGPAKLMAVVKANAYNHGVEKVAPVIAAHGADAFGVA
CCEEEEEEEHHHHHHHHHHHHHHCCHHHEEHHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
TLAEAMQLRDIGISQEVLCWIWTPEQDFRAAIDRNIDLAVISPAHAKALIETDAEHIRVS
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEEEEE
IKIDSGLHRSGVDEQEWEGVFSALAAAPHIEVTGMFTHLACADEPENPETDRQIIAFRRA
EEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHH
LALARKHGLECPVNHVCNSPAFLTRSDLHMEMVRPGLAFYGLEPVAGLEHGLKPAMTWEA
HHHHHHCCCCCCHHHHCCCCCEEECCCCHHHHHCCCCEEECCCCHHHHHHCCCCCEEHHH
KVSVVKQIEAGQGTSYGLTWRAEDRGFVAVVPAGYADGMPRHAQGKFSVTIDGLDYPQVG
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHH
RVCMDQFVISLGDNPHGVEAGAKAVIFGENGHDATDFAERLDTINYEVVCRPTGRTVRAY
HHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEE
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA