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The map label for this gene is map1 [H]

Identifier: 62389448

GI number: 62389448

Start: 571478

End: 572272

Strand: Direct

Name: map1 [H]

Synonym: cg0649

Alternate gene names: 62389448

Gene position: 571478-572272 (Clockwise)

Preceding gene: 62389447

Following gene: 62389449

Centisome position: 17.41

GC content: 60.38

Gene sequence:

>795_bases
ATGGGTTTCCGTTCCAAGAAGAAGGTTATTGCGGCAAAGACCGCCGCTGAGCTGGACGCGATGCAGGCGGCGGGTGAGAT
CGTCGGCAAGGCTTTGCAGGCTGTGCGCGCTGAGGCTAAAGCTGGCATGAGCACGTGGGATCTGGATCAGATCGCGGAGC
AGGTTATCCGCGATGCTGGCGCCGTTCCTACATTCCTGGGTTACCAGGGTTTTCCGGCATCAGTGTGCGCTTCGGTCAAT
GAGGTGATTGTTCACGGCATTCCATCCAAGGAGACCATCTTGGAGGAAGGCGATCTGGTGTCCATCGACTGCGGCGCAAC
CTTTGATGGTTGGGTCGGCGATTCCGCGTGGAGCTTCGGCATCGGCGAGCTGGACGAGGACGTCCAGGGTCTCAACTTGG
CTACCGAGTGGGTCCTCATGGAAGGCATGAAGGCCATGGTTCCAGGCAACCGTTTGACCGATGTCTCCCACGCTCTCGAG
GTCGCAACCCGCAAGGCTGAGTCCAAGTTCGGCGTCGCGCTCGGCATCGTCGATGGCTACGGCGGACACGGCATTGGCCG
CCACATGCACGAGGAGCCATACTTGGCTAATGAGGGCAAGGCCGGCAAGGGCCCTGTGATTCAGGAGGGCTCCGTGCTCG
CCATTGAGCCTATGCTCACCCTCGGCACCGAAGATTCCGCAGTGCTGGAAGATGATTGGACTGTCGTGACTCTCGACGGT
TCATGGGCATCACACTGGGAGCACACCGTTGCAGCCACCAAGGGCGGCCCGCGCATCCTCACGCCGCGTTATTAA

Upstream 100 bases:

>100_bases
GTGGAAGTACTCACCTCAAGGTGGCCGGAACCGCATGCATTGTGCGGTGCCGGCCACCTTTGGTTTTAACAGTTTAATTT
GAAGAAAGAGACGTGGAAGC

Downstream 100 bases:

>100_bases
AATGATGCTTTTCGACGCATCCCCACGTTTTGGGGCTAAAAGTTGCCCGGTTGAGCAAAGGTTTGCGACCTCCCCGGCGT
GCCGCCAGGGGAGGAGGCGA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAGAVPTFLGYQGFPASVCASVN
EVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFGIGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALE
VATRKAESKFGVALGIVDGYGGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
SWASHWEHTVAATKGGPRILTPRY

Sequences:

>Translated_264_residues
MGFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAGAVPTFLGYQGFPASVCASVN
EVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFGIGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALE
VATRKAESKFGVALGIVDGYGGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
SWASHWEHTVAATKGGPRILTPRY
>Mature_263_residues
GFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAGAVPTFLGYQGFPASVCASVNE
VIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFGIGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALEV
ATRKAESKFGVALGIVDGYGGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDGS
WASHWEHTVAATKGGPRILTPRY

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=259, Percent_Identity=32.4324324324324, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI164420681, Length=254, Percent_Identity=31.1023622047244, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1786364, Length=257, Percent_Identity=35.0194552529183, Blast_Score=161, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=31.3953488372093, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=31.8548387096774, Blast_Score=135, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=31.7269076305221, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=31.5789473684211, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27961; Mature: 27830

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
AVPTFLGYQGFPASVCASVNEVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFG
CCCHHHCCCCCCHHHHHHHHHHHEECCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
IGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALEVATRKAESKFGVALGIVDGY
CCCCCHHHHCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCEEEECCCCCEEEECCCEEEEECC
SWASHWEHTVAATKGGPRILTPRY
CCHHHHHHHEEECCCCCEECCCCC
>Mature Secondary Structure 
GFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
AVPTFLGYQGFPASVCASVNEVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFG
CCCHHHCCCCCCHHHHHHHHHHHEECCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
IGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALEVATRKAESKFGVALGIVDGY
CCCCCHHHHCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCEEEECCCCCEEEECCCEEEEECC
SWASHWEHTVAATKGGPRILTPRY
CCHHHHHHHEEECCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]