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The map label for this gene is udgA1 [H]

Identifier: 62389258

GI number: 62389258

Start: 381949

End: 383112

Strand: Direct

Name: udgA1 [H]

Synonym: cg0435

Alternate gene names: 62389258

Gene position: 381949-383112 (Clockwise)

Preceding gene: 62389255

Following gene: 62389262

Centisome position: 11.64

GC content: 41.75

Gene sequence:

>1164_bases
ATGAAAATTGCCGTCGCAGGGCTCGGATATGTTGGGCTTTCAAATGCAGCTCTCCTCTCTAAAAATCATAAAGTTGTTGC
AGTTGACATTGATGAAGAACGAGTGAAACTAGTTCAAGAATTTCGTTCGCCAATTGTCGATAGCGATCTCGAAGAATATC
TGTCCACTAAGCCTCAAAACTTAACTGCCACAACGGACGCCGAAGCCGCTTACAAAGGCGCAGATTTTATTGTTATTGCA
ACGCCAACTAATTACGACCCAGAGTCAAACTTTTTTGATACTTCCAGCGTTGAGTCCGTAATTGAGATAGTCCTTAAGGT
TTCTCCTGGATCCACAATCGTAATTAAATCGACTATCCCTGTTGGTTTTACATCGGAACTACGCATTAAGCATCCAGAAG
CTTCGATTATTTTTTCACCTGAGTTCCTGCGTGAAGGCCGAGCATTCTACGACAATCTCTACCCATCCAGAGTTGTCGTT
GGTGATCGCAGTCCTCTGGGGGAAGAATTTGCGACTCTGTTAGCTGAGGGGGCAAAAGAAAAGCCTCCGATTCTACTTAC
GGACTCAACTGAGGCAGAGGCGATTAAATTATTTTCTAATACATATCTTGCACTGCGAGTTGCTTTTTTCAACGAACTGG
ATACTTATGCGTCTGTTCGAAGCTTGGATACTAAGCAGATTATTGAAGGGGTAGGGCTCGATCCACGTATTGGATCTCAT
TACAATAATCCTTCATTTGGATATGGCGGATATTGTCTTCCGAAAGATACGAAACAGCTTCTCGCCAACTATAAGGATGT
CCCGCAGAATCTAATCTCTGCAGTAGTCCAAGCAAATAAGACTCGTAAGGACTTTATTGCAGAGGATATCCTCAGTAAAT
CACCTACTGTAGTTGGAATTTACCGCCTTGTAATGAAGTCTGGATCAGATAACTTTCGTTCTTCTTCTATTCAAGGAGTC
ATGAAACGAATTAAGGCCAAGGGAATCGAAATTGTAGTATTTGAACCGAATCTCGGAGAAGAAACTTTCTACAATTCGAA
GATCCTTAATGACATCGAAGAGTTTAAGGATTACTGCGACATCATTATTGCAAATCGTCCAACCGATGAGCTTTCTGATG
TACCAGAAAAAGTTTATACACGTGATATTTTCCAGCGTGACTAA

Upstream 100 bases:

>100_bases
TATACTCGTCAAGGGCCTTCGATAAAACAAAGACAATTTTCCCCCGACGGGACAATCTGAAAACTTGCTGTATCAATAAA
ACACGAAAAGGAATACTTTT

Downstream 100 bases:

>100_bases
GTGGAAAGAATCTTTTGTTGATGACCCGCTACAAATCATGAGTCCCTAACAAATCTTCAACTAGTGCCATACACGAGACT
TGTGTAGGGCACTAAGTCAT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKIAVAGLGYVGLSNAALLSKNHKVVAVDIDEERVKLVQEFRSPIVDSDLEEYLSTKPQNLTATTDAEAAYKGADFIVIA
TPTNYDPESNFFDTSSVESVIEIVLKVSPGSTIVIKSTIPVGFTSELRIKHPEASIIFSPEFLREGRAFYDNLYPSRVVV
GDRSPLGEEFATLLAEGAKEKPPILLTDSTEAEAIKLFSNTYLALRVAFFNELDTYASVRSLDTKQIIEGVGLDPRIGSH
YNNPSFGYGGYCLPKDTKQLLANYKDVPQNLISAVVQANKTRKDFIAEDILSKSPTVVGIYRLVMKSGSDNFRSSSIQGV
MKRIKAKGIEIVVFEPNLGEETFYNSKILNDIEEFKDYCDIIIANRPTDELSDVPEKVYTRDIFQRD

Sequences:

>Translated_387_residues
MKIAVAGLGYVGLSNAALLSKNHKVVAVDIDEERVKLVQEFRSPIVDSDLEEYLSTKPQNLTATTDAEAAYKGADFIVIA
TPTNYDPESNFFDTSSVESVIEIVLKVSPGSTIVIKSTIPVGFTSELRIKHPEASIIFSPEFLREGRAFYDNLYPSRVVV
GDRSPLGEEFATLLAEGAKEKPPILLTDSTEAEAIKLFSNTYLALRVAFFNELDTYASVRSLDTKQIIEGVGLDPRIGSH
YNNPSFGYGGYCLPKDTKQLLANYKDVPQNLISAVVQANKTRKDFIAEDILSKSPTVVGIYRLVMKSGSDNFRSSSIQGV
MKRIKAKGIEIVVFEPNLGEETFYNSKILNDIEEFKDYCDIIIANRPTDELSDVPEKVYTRDIFQRD
>Mature_387_residues
MKIAVAGLGYVGLSNAALLSKNHKVVAVDIDEERVKLVQEFRSPIVDSDLEEYLSTKPQNLTATTDAEAAYKGADFIVIA
TPTNYDPESNFFDTSSVESVIEIVLKVSPGSTIVIKSTIPVGFTSELRIKHPEASIIFSPEFLREGRAFYDNLYPSRVVV
GDRSPLGEEFATLLAEGAKEKPPILLTDSTEAEAIKLFSNTYLALRVAFFNELDTYASVRSLDTKQIIEGVGLDPRIGSH
YNNPSFGYGGYCLPKDTKQLLANYKDVPQNLISAVVQANKTRKDFIAEDILSKSPTVVGIYRLVMKSGSDNFRSSSIQGV
MKRIKAKGIEIVVFEPNLGEETFYNSKILNDIEEFKDYCDIIIANRPTDELSDVPEKVYTRDIFQRD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=369, Percent_Identity=27.6422764227642, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI296040438, Length=270, Percent_Identity=26.2962962962963, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI296040443, Length=357, Percent_Identity=24.3697478991597, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=62.1134020618557, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI48994968, Length=377, Percent_Identity=25.4641909814324, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560350, Length=393, Percent_Identity=26.7175572519084, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136908, Length=381, Percent_Identity=27.5590551181102, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 42941; Mature: 42941

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVAGLGYVGLSNAALLSKNHKVVAVDIDEERVKLVQEFRSPIVDSDLEEYLSTKPQN
CEEEEEECCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
LTATTDAEAAYKGADFIVIATPTNYDPESNFFDTSSVESVIEIVLKVSPGSTIVIKSTIP
CEECCCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCC
VGFTSELRIKHPEASIIFSPEFLREGRAFYDNLYPSRVVVGDRSPLGEEFATLLAEGAKE
CCCCCCEEEECCCCEEEECHHHHHCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCC
KPPILLTDSTEAEAIKLFSNTYLALRVAFFNELDTYASVRSLDTKQIIEGVGLDPRIGSH
CCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
YNNPSFGYGGYCLPKDTKQLLANYKDVPQNLISAVVQANKTRKDFIAEDILSKSPTVVGI
CCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHH
YRLVMKSGSDNFRSSSIQGVMKRIKAKGIEIVVFEPNLGEETFYNSKILNDIEEFKDYCD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
IIIANRPTDELSDVPEKVYTRDIFQRD
EEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAVAGLGYVGLSNAALLSKNHKVVAVDIDEERVKLVQEFRSPIVDSDLEEYLSTKPQN
CEEEEEECCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
LTATTDAEAAYKGADFIVIATPTNYDPESNFFDTSSVESVIEIVLKVSPGSTIVIKSTIP
CEECCCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCC
VGFTSELRIKHPEASIIFSPEFLREGRAFYDNLYPSRVVVGDRSPLGEEFATLLAEGAKE
CCCCCCEEEECCCCEEEECHHHHHCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCC
KPPILLTDSTEAEAIKLFSNTYLALRVAFFNELDTYASVRSLDTKQIIEGVGLDPRIGSH
CCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
YNNPSFGYGGYCLPKDTKQLLANYKDVPQNLISAVVQANKTRKDFIAEDILSKSPTVVGI
CCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHH
YRLVMKSGSDNFRSSSIQGVMKRIKAKGIEIVVFEPNLGEETFYNSKILNDIEEFKDYCD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
IIIANRPTDELSDVPEKVYTRDIFQRD
EEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]