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The map label for this gene is rmlB2 [C]

Identifier: 62389221

GI number: 62389221

Start: 338794

End: 339729

Strand: Direct

Name: rmlB2 [C]

Synonym: cg0391

Alternate gene names: 62389221

Gene position: 338794-339729 (Clockwise)

Preceding gene: 62389220

Following gene: 62389224

Centisome position: 10.32

GC content: 55.98

Gene sequence:

>936_bases
ATGCGCACAGTAGTTACCGGCGGTGCCGGCTTCATCGGATCCCATCTCGTTGACCTTTTGATCAAGGAAGGCCACGAGGT
CGTTGTGATCGATAACCTCTCCCGCGGACGCCTGGAGAATCTCTCCGATGCGGAAGCCACCGGAAAACTCACCTTTGTGG
AAGCCGATCTTCTCGACGTTGATTTCAACGAGTTTCTAGGAACCCACAAGCCTGAGGTTATTTTCCACCTGGCAGCGCAA
ATCGATGTGCGCCACTCTGTTGTAGATCCTCTTCACGACGCCGAAACCAACATTTTGTCCACCATCCGCATCGCTGACGC
TGCCCGCCAGCACGGTGTTCGCAAGGTTGTCTTTACCTCCTCAGGCGGTTCCATTTACGGTGAGCCTTCGGAATTCCCAG
TTGATGAAACCGTGCCAGTGGATCCACATTCCCCTTATGCGGCATCCAAGGTGTCCGGTGAAATTTACCTGAACACCTTC
CGCCACCTGTACGGCTTAGACTGTTCTCACATCGCACCGGCAAATGTTTACGGCCCACGCCAAGATCCACACGGTGAAGC
AGGAGTTGTGGCCATTTTCGCGCTGCGACTTCTGGGAGGCCTGGACACCAAGGTATTCGGCGACGGCGGAAACACCCGCG
ACTACGTCTACGTCGGTGACGTAGTTCGTGCTTTCTACCTGGCTTCTGGGGAAATCGGTGGGGGAGAGCGCTTCAACATT
GGCACCTCTGTGGAAACCTCTGACCGCCAGCTGCACACCCTCGTGGCCACTGCGGCAGGTTCCAAAGATGATCCTGAATA
TGCACCTGCACGTCTCGGCGATGTGCCACGCAGTGCACTCAGCTTCGGCAAGGCCAAAGAGGTGCTTGGTTGGGAGCCTG
AGGTGAACATCGAACAAGGTGTGGCCAAGACTGTGGAGTACTTCCGCACTCACTAG

Upstream 100 bases:

>100_bases
CCCGTTCATGCTGGGCTTTGGTGCGGTGATGGCAACTATTTGTCTGATCATTGTGAGTTTTAGTGCACGCCGATTCTGAG
AAACAACTAAAGTGAGCCAC

Downstream 100 bases:

>100_bases
GGGAAAATCCACCACAAATCGCTCTGATCAGTGGAAACGTGGTGGGTTTTTGCATTTTCCGCACTCAAAAACGCAAGGAT
CCACCACAGATCTCAAGATA

Product: dTDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQ
IDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTF
RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNI
GTSVETSDRQLHTLVATAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH

Sequences:

>Translated_311_residues
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQ
IDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTF
RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNI
GTSVETSDRQLHTLVATAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH
>Mature_311_residues
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDVDFNEFLGTHKPEVIFHLAAQ
IDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTSSGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTF
RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNI
GTSVETSDRQLHTLVATAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQGVAKTVEYFRTH

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=318, Percent_Identity=30.188679245283, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI42516563, Length=313, Percent_Identity=28.7539936102236, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI56237023, Length=329, Percent_Identity=29.483282674772, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56118217, Length=329, Percent_Identity=29.483282674772, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI189083684, Length=329, Percent_Identity=29.483282674772, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4504031, Length=352, Percent_Identity=26.9886363636364, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=31.1572700296736, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI48994969, Length=332, Percent_Identity=31.6265060240964, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=29.2537313432836, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788366, Length=343, Percent_Identity=24.4897959183673, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788365, Length=297, Percent_Identity=25.2525252525253, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=324, Percent_Identity=29.320987654321, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=28.6153846153846, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982035, Length=335, Percent_Identity=29.2537313432836, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982038, Length=337, Percent_Identity=29.080118694362, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115532424, Length=324, Percent_Identity=25.3086419753086, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17507723, Length=344, Percent_Identity=26.453488372093, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133901786, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI133901790, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI133901788, Length=341, Percent_Identity=26.099706744868, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17539422, Length=341, Percent_Identity=26.099706744868, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17539424, Length=341, Percent_Identity=26.099706744868, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=328, Percent_Identity=28.0487804878049, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=29.3929712460064, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19923002, Length=334, Percent_Identity=28.7425149700599, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24158427, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33537; Mature: 33537

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDV
CCEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEC
DFNEFLGTHKPEVIFHLAAQIDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTS
CHHHHHCCCCCCEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
SGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTFRHLYGLDCSHIAPANVYGPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCCCC
QDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNI
CCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEC
GTSVETSDRQLHTLVATAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQG
CCCCCCCCHHHHHHEEECCCCCCCCCCCCHHHCCCCHHHHHHCCHHHHCCCCCCCCHHHH
VAKTVEYFRTH
HHHHHHHHHCC
>Mature Secondary Structure
MRTVVTGGAGFIGSHLVDLLIKEGHEVVVIDNLSRGRLENLSDAEATGKLTFVEADLLDV
CCEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEC
DFNEFLGTHKPEVIFHLAAQIDVRHSVVDPLHDAETNILSTIRIADAARQHGVRKVVFTS
CHHHHHCCCCCCEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
SGGSIYGEPSEFPVDETVPVDPHSPYAASKVSGEIYLNTFRHLYGLDCSHIAPANVYGPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCCCC
QDPHGEAGVVAIFALRLLGGLDTKVFGDGGNTRDYVYVGDVVRAFYLASGEIGGGERFNI
CCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEHHHHHHHHHHCCCCCCCCEEEC
GTSVETSDRQLHTLVATAAGSKDDPEYAPARLGDVPRSALSFGKAKEVLGWEPEVNIEQG
CCCCCCCCHHHHHHEEECCCCCCCCCCCCHHHCCCCHHHHHHCCHHHHCCCCCCCCHHHH
VAKTVEYFRTH
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]