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The map label for this gene is tadA [H]

Identifier: 62389126

GI number: 62389126

Start: 243483

End: 243914

Strand: Direct

Name: tadA [H]

Synonym: cg0281

Alternate gene names: 62389126

Gene position: 243483-243914 (Clockwise)

Preceding gene: 62389125

Following gene: 62389127

Centisome position: 7.42

GC content: 59.95

Gene sequence:

>432_bases
ATGCGCCATGCTTTGGATATTGCTCGCCAAACCCCTGAGGGGGACGTTCCCGTTGGCGCCGTCATTTACGCGCCGACCGG
GGAGATCCTGGCGACCGCAACGAACCGTCGAGAAGCAGACCGCGATCCCACGGCCCACGCCGAAATTATTGCTTTACGAC
GAGCCGCCCGCCGTTTTTCCGACGGCTGGCGGCTGAGTGACTGCACCGCGGTGGTCACCTTGGAGCCCTGCAGTATGTGC
GCCGGCGCCTTGGTGGGTGCTCGAATCGGACGCATCGTATTCGGAGCATTTGAGCCCCGAACCGGCGCCTGTGGATCTGT
ATTTGACGTGGTTCGAGACCCCGCGGTGTTGCACAAAGTGGAAGTCAGTGGAGGAATCCTCGAGCCTGAATGTGCTGCCT
TGATGACCGAATTTTTCGAACTTCACAGGTAA

Upstream 100 bases:

>100_bases
CGGAAGAACTCGGTTTTGATAATGATCTGGCTCGGGTGGTGGGATTCGACTAGTGGGCGTTTTACCTGTGCAGGCGCGCA
TCAAAGACGATGAGCGCCGC

Downstream 100 bases:

>100_bases
CGGATTTATATCAATTTCAGGGCGTGGCGAGCTTTTAGTGATTCACGCTCCTACGGTGGGTATCACAAATACCTCAACTA
GAAGTAGGAGATGAGCACCA

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MRHALDIARQTPEGDVPVGAVIYAPTGEILATATNRREADRDPTAHAEIIALRRAARRFSDGWRLSDCTAVVTLEPCSMC
AGALVGARIGRIVFGAFEPRTGACGSVFDVVRDPAVLHKVEVSGGILEPECAALMTEFFELHR

Sequences:

>Translated_143_residues
MRHALDIARQTPEGDVPVGAVIYAPTGEILATATNRREADRDPTAHAEIIALRRAARRFSDGWRLSDCTAVVTLEPCSMC
AGALVGARIGRIVFGAFEPRTGACGSVFDVVRDPAVLHKVEVSGGILEPECAALMTEFFELHR
>Mature_143_residues
MRHALDIARQTPEGDVPVGAVIYAPTGEILATATNRREADRDPTAHAEIIALRRAARRFSDGWRLSDCTAVVTLEPCSMC
AGALVGARIGRIVFGAFEPRTGACGSVFDVVRDPAVLHKVEVSGGILEPECAALMTEFFELHR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=49.3055555555556, Blast_Score=136, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17541138, Length=143, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322425, Length=153, Percent_Identity=32.6797385620915, Blast_Score=68, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=33.5616438356164, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15388; Mature: 15388

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHALDIARQTPEGDVPVGAVIYAPTGEILATATNRREADRDPTAHAEIIALRRAARRFS
CCCHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
DGWRLSDCTAVVTLEPCSMCAGALVGARIGRIVFGAFEPRTGACGSVFDVVRDPAVLHKV
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCHHHEEE
EVSGGILEPECAALMTEFFELHR
ECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRHALDIARQTPEGDVPVGAVIYAPTGEILATATNRREADRDPTAHAEIIALRRAARRFS
CCCHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
DGWRLSDCTAVVTLEPCSMCAGALVGARIGRIVFGAFEPRTGACGSVFDVVRDPAVLHKV
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHCCCHHHEEE
EVSGGILEPECAALMTEFFELHR
ECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]