Click here to switch to the map view.

The map label for this gene is rhtC [H]

Identifier: 62389040

GI number: 62389040

Start: 158155

End: 158835

Strand: Direct

Name: rhtC [H]

Synonym: cg0183

Alternate gene names: 62389040

Gene position: 158155-158835 (Clockwise)

Preceding gene: 62389039

Following gene: 62389041

Centisome position: 4.82

GC content: 54.04

Gene sequence:

>681_bases
ATGACAACAGCACAGTTTCTAGCGCTTTTTCTGGTGTGGATCGCAGCAATTGCATCCCCTGGGCCAGACCTTTTCCAGAT
CATCAGGCTAAGTGCCAAAAACCGCCGTGATGGCGTACTGACTGCCGTAGGCATCATGGTGGGAAACTCCATCTGGATCA
TAGCCAGCCTCCTTGGGCTCTCGGCACTGATCTCCACGTATCCAGCAATTTTGAACCTGTTGCAGCTCGTCGGTGGCGGT
TATTTGACCTGGATGGGCATCGGGGCGGTGAGGTCATGGTGGACGAAACGCTCCACACAGCAAGCTGCAGCGGATTCTCA
AGCTGTAGAGAATACGTTGGTGACAGCCACGGCTGCATCTGTCGGAGTGTGGCCAGCTATTCGATCTGGCATTGCTACCA
ACTTGTCCAACCCCAAAGCTGTGCTGTTTTTTGGTTCCGTTTTCGCCCAATTTGTTAGACCTGACATGGGAATCGGGTGG
AGTATTTTCATTGGAGTCTTCCTCACCCTCACTGGCCTGCTGTGGTTTGTGGGGTTCGCCGTCTTGGTCCGCAAACTAGC
CGCTGGCCTCACCCGAAATGGAGCCATCATCGACCTGCTAACGGGGGTGATTTTCATCGGGCTGGGAATGTTCATGATCT
TCGAGGGGGTTGTAGGAATCGGTGGCAGGGTAGTGGGTTAG

Upstream 100 bases:

>100_bases
CAAAGCCTTGGGCTTTACCCATATCGGACTGACCTCCTTGAGCATCCTCCAGCAGGCCATTGGGGTCACAGAGCTGAAGG
CTGCCTAAGATATAACTCCG

Downstream 100 bases:

>100_bases
CCCCGCCCCCAGGACGTCACTAGACTTAGGCACTATGCAACCTGAAGAAGTGCACATCAAGGACGAGACCATCAAGTTAG
GTCAGTTCATCAAATTGGCC

Product: LysE type translocator

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTTAQFLALFLVWIAAIASPGPDLFQIIRLSAKNRRDGVLTAVGIMVGNSIWIIASLLGLSALISTYPAILNLLQLVGGG
YLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAASVGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGW
SIFIGVFLTLTGLLWFVGFAVLVRKLAAGLTRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG

Sequences:

>Translated_226_residues
MTTAQFLALFLVWIAAIASPGPDLFQIIRLSAKNRRDGVLTAVGIMVGNSIWIIASLLGLSALISTYPAILNLLQLVGGG
YLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAASVGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGW
SIFIGVFLTLTGLLWFVGFAVLVRKLAAGLTRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG
>Mature_225_residues
TTAQFLALFLVWIAAIASPGPDLFQIIRLSAKNRRDGVLTAVGIMVGNSIWIIASLLGLSALISTYPAILNLLQLVGGGY
LTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAASVGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGWS
IFIGVFLTLTGLLWFVGFAVLVRKLAAGLTRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=217, Percent_Identity=34.1013824884793, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786522, Length=132, Percent_Identity=34.8484848484849, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23889; Mature: 23757

Theoretical pI: Translated: 11.45; Mature: 11.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQFLALFLVWIAAIASPGPDLFQIIRLSAKNRRDGVLTAVGIMVGNSIWIIASLLGL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
SALISTYPAILNLLQLVGGGYLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGWSIFIGVFLTLTGLLWFVGFA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVRKLAAGLTRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure 
TTAQFLALFLVWIAAIASPGPDLFQIIRLSAKNRRDGVLTAVGIMVGNSIWIIASLLGL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
SALISTYPAILNLLQLVGGGYLTWMGIGAVRSWWTKRSTQQAAADSQAVENTLVTATAAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVWPAIRSGIATNLSNPKAVLFFGSVFAQFVRPDMGIGWSIFIGVFLTLTGLLWFVGFA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVRKLAAGLTRNGAIIDLLTGVIFIGLGMFMIFEGVVGIGGRVVG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]