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The map label for this gene is luxI

Identifier: 59714107

GI number: 59714107

Start: 1048783

End: 1049355

Strand: Reverse

Name: luxI

Synonym: VF_A0924

Alternate gene names: 59714107

Gene position: 1049355-1048783 (Counterclockwise)

Preceding gene: 59714109

Following gene: 59714106

Centisome position: 78.88

GC content: 34.38

Gene sequence:

>573_bases
ATGATAAAAAAATCGGACTTTTTGGGCATTCCATCAGAGGAGTATAGAGGTATTCTTAGTCTTCGTTATCAGGTATTTAA
ACGAAGACTGGAGTGGGACTTGGTAAGTGAGGATAATCTTGAATCAGATGAATATGATAACTCAAATGCAGAATATATTT
ATGCTTGTGATGATGCGGAAGAGGTAAATGGCTGTTGGCGTTTGTTACCTACAACGGGTGATTACATGTTAAAAACTGTT
TTTCCTGAATTGCTCGGAGATCAAGTAGCCCCAAGAGATCCAAATATAGTCGAATTAAGCCGTTTTGCTGTGGGAAAAAA
TAGCTCAAAAATAAATAACTCTGCTAGTGAAATAACAATGAAATTGTTTCAAGCTATATATAAACACGCAGTTAGTCAAG
GTATTACAGAATATGTAACAGTAACATCAATAGCAATAGAGCGATTTCTGAAACGTATTAAAGTTCCTTGTCATCGCATT
GGTGATAAGGAGATTCATTTATTAGGTAATACTAGATCTGTTGTATTGTCTATGCCTATTAATGATCAGTTTAGAAAAGC
TGTATCAAATTAA

Upstream 100 bases:

>100_bases
GGAAACGTGGTGTTAACATTGCAGCTGTAGGATGGTACAGGTTTCCGTAATGCATCAGTTTGTTATGATCATGTAAAATA
AGAGAGGTTGCATGGCTGTA

Downstream 100 bases:

>100_bases
TACTCGAACATAATACATATAGTTAGTAGGGGAAATAATGATTAAATGTATTCCGATGATAATTAAAGGCGTAGTTCAAG
ATTTTGATAATAACGCTTGT

Product: 3-oxo-C6-HSL autoinducer synthesis protein LuxI

Products: NA

Alternate protein names: Autoinducer synthesis protein luxI

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIKKSDFLGIPSEEYRGILSLRYQVFKRRLEWDLVSEDNLESDEYDNSNAEYIYACDDAEEVNGCWRLLPTTGDYMLKTV
FPELLGDQVAPRDPNIVELSRFAVGKNSSKINNSASEITMKLFQAIYKHAVSQGITEYVTVTSIAIERFLKRIKVPCHRI
GDKEIHLLGNTRSVVLSMPINDQFRKAVSN

Sequences:

>Translated_190_residues
MIKKSDFLGIPSEEYRGILSLRYQVFKRRLEWDLVSEDNLESDEYDNSNAEYIYACDDAEEVNGCWRLLPTTGDYMLKTV
FPELLGDQVAPRDPNIVELSRFAVGKNSSKINNSASEITMKLFQAIYKHAVSQGITEYVTVTSIAIERFLKRIKVPCHRI
GDKEIHLLGNTRSVVLSMPINDQFRKAVSN
>Mature_190_residues
MIKKSDFLGIPSEEYRGILSLRYQVFKRRLEWDLVSEDNLESDEYDNSNAEYIYACDDAEEVNGCWRLLPTTGDYMLKTV
FPELLGDQVAPRDPNIVELSRFAVGKNSSKINNSASEITMKLFQAIYKHAVSQGITEYVTVTSIAIERFLKRIKVPCHRI
GDKEIHLLGNTRSVVLSMPINDQFRKAVSN

Specific function: Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone) also known as VAI or N-(beta- ketocaproyl)homoserine lactone or 3-oxo-N-(tetrahydro-2-oxo-3- furanyl)-hexanamide, an autoinducer molecule which binds to luxR and thus acts in bio

COG id: COG3916

COG function: function code TQ; N-acyl-L-homoserine lactone synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autoinducer synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXJ_VIBF1 (P35328)

Other databases:

- EMBL:   M96844
- EMBL:   CP000021
- RefSeq:   YP_206882.1
- ProteinModelPortal:   P35328
- SMR:   P35328
- STRING:   P35328
- GeneID:   3280753
- GenomeReviews:   CP000021_GR
- KEGG:   vfi:VF_A0924
- NMPDR:   fig|312309.3.peg.3315
- eggNOG:   COG3916
- HOGENOM:   HBG368426
- ProtClustDB:   CLSK2396396
- BioCyc:   VFIS312309:VFA0924-MONOMER
- GO:   GO:0008218
- InterPro:   IPR016181
- InterPro:   IPR001690
- InterPro:   IPR018311
- Gene3D:   G3DSA:3.40.630.30
- PRINTS:   PR01549

Pfam domain/function: PF00765 Autoind_synth; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.184

Molecular weight: Translated: 21713; Mature: 21713

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00949 AUTOINDUCER_SYNTH_1; PS51187 AUTOINDUCER_SYNTH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKSDFLGIPSEEYRGILSLRYQVFKRRLEWDLVSEDNLESDEYDNSNAEYIYACDDAE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
EVNGCWRLLPTTGDYMLKTVFPELLGDQVAPRDPNIVELSRFAVGKNSSKINNSASEITM
HHCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCCCCCCCHHHHHHH
KLFQAIYKHAVSQGITEYVTVTSIAIERFLKRIKVPCHRIGDKEIHLLGNTRSVVLSMPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCEEEEECCC
NDQFRKAVSN
CHHHHHHHCC
>Mature Secondary Structure
MIKKSDFLGIPSEEYRGILSLRYQVFKRRLEWDLVSEDNLESDEYDNSNAEYIYACDDAE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
EVNGCWRLLPTTGDYMLKTVFPELLGDQVAPRDPNIVELSRFAVGKNSSKINNSASEITM
HHCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHCCCCCCCCCCHHHHHHH
KLFQAIYKHAVSQGITEYVTVTSIAIERFLKRIKVPCHRIGDKEIHLLGNTRSVVLSMPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCEEEEECCC
NDQFRKAVSN
CHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA