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The map label for this gene is luxA [H]

Identifier: 59714104

GI number: 59714104

Start: 1045277

End: 1046344

Strand: Reverse

Name: luxA [H]

Synonym: VF_A0921

Alternate gene names: 59714104

Gene position: 1046344-1045277 (Counterclockwise)

Preceding gene: 59714105

Following gene: 59714103

Centisome position: 78.65

GC content: 38.58

Gene sequence:

>1068_bases
ATGAAGTTTGGTAACATTTATTTTTCGTATCAGCCACCAGGCGAAACTCATAAGCAGATAATGGATCGTTTTGTGAGACT
AGGGAGCGTTTCTGAAGAGCTTGGTTTTGATACATATTGGACGTTAGAACATCATTTTACTGAATTCGGTTTAACTGGGA
GCTTGTTTGTTTCCGCTGCTAATTTATTAGGAAGAACAAAAACATTGAAAGTAGGAACTATGGGGGTCGTTGTACCTACT
GCTCACCCCGTACGGCAAGCAGAGGATGTATTGCTGTTAGATCAACTTTCTAAAGGTCGATTTAATTTTGGTGTTGTTAG
AGGCCTATATCACAAGGATTTTCGGGTCTTTGGGGTCAATATGGAAGAATCTCGTGAAATAACACAAGATTTTCATCAGA
TGATAATGAAGAGCTTTGATGAAGGAGCGATCCATAGTAATAGTAAACATATTGATTTTCCAGACGTTAATGTTTATCCA
ACAAAGTACTCTAAAGAAATTAGGACTTGTATGACAGCGGAGTCAGCTAGTACTACTGAGTGGCTAGCAAGGCAAGGGAT
GCCAATGGTACTTAGTTGGATTATAGGAACAAATGAGAAAAAAACACAAATGGAGCTATATAATGAAATAGCGACAGAAC
ATGGCCACGACATAAGTAAGATTGATCATTGTTTAACCTATATTTGTTCCGTTCACGAAGATGGGGATAGAGCTCGTGAG
GTATGTCGGAAGTTCTTGATCAGTTTTTACGATTCTTATGTAAATGCAACCAACATTTTTAATGATAGTGATCAAACTCG
AGGTTACGATTATCACAAAGGCCAGTGGAGAGATTTTGTATTACAAGGTCATACTGATACGAATCGACGTGTTGATTATA
GTCATGGACTTAATCCTGTTGGAACTCCTGCAGAGTGCCTTGAGATTATTCAGCGTGATATTGATGCGACTGGTATTACT
AACGTCACCTGTGGTTTTGAGGCTAATGGCACTGAAGAAGAAATTATTGCTTCGATGGAACTCTTCATGACCAAGGTTGC
CCCTTTCTTAAAAGAACCTCAAAAATAA

Upstream 100 bases:

>100_bases
GAAGACTTGACAAGTACAACAGTTAAAGAGCGAAGATTAAGAAATAAAATAGAGAATGAGCTATTGGAATTAGCCTAATT
ATTAAGAAGGAATAGAGATA

Downstream 100 bases:

>100_bases
GGAATATATTATGAATTTTGGATTATTTTTTCTCAACTTTCAGAAGAATGGGATAACATCGGAGGAAACGTTAAATTGTA
TGGTTGATACTGTCACTTTA

Product: luciferase alpha chain LuxA

Products: NA

Alternate protein names: Bacterial luciferase alpha chain [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKFGNIYFSYQPPGETHKQIMDRFVRLGSVSEELGFDTYWTLEHHFTEFGLTGSLFVSAANLLGRTKTLKVGTMGVVVPT
AHPVRQAEDVLLLDQLSKGRFNFGVVRGLYHKDFRVFGVNMEESREITQDFHQMIMKSFDEGAIHSNSKHIDFPDVNVYP
TKYSKEIRTCMTAESASTTEWLARQGMPMVLSWIIGTNEKKTQMELYNEIATEHGHDISKIDHCLTYICSVHEDGDRARE
VCRKFLISFYDSYVNATNIFNDSDQTRGYDYHKGQWRDFVLQGHTDTNRRVDYSHGLNPVGTPAECLEIIQRDIDATGIT
NVTCGFEANGTEEEIIASMELFMTKVAPFLKEPQK

Sequences:

>Translated_355_residues
MKFGNIYFSYQPPGETHKQIMDRFVRLGSVSEELGFDTYWTLEHHFTEFGLTGSLFVSAANLLGRTKTLKVGTMGVVVPT
AHPVRQAEDVLLLDQLSKGRFNFGVVRGLYHKDFRVFGVNMEESREITQDFHQMIMKSFDEGAIHSNSKHIDFPDVNVYP
TKYSKEIRTCMTAESASTTEWLARQGMPMVLSWIIGTNEKKTQMELYNEIATEHGHDISKIDHCLTYICSVHEDGDRARE
VCRKFLISFYDSYVNATNIFNDSDQTRGYDYHKGQWRDFVLQGHTDTNRRVDYSHGLNPVGTPAECLEIIQRDIDATGIT
NVTCGFEANGTEEEIIASMELFMTKVAPFLKEPQK
>Mature_355_residues
MKFGNIYFSYQPPGETHKQIMDRFVRLGSVSEELGFDTYWTLEHHFTEFGLTGSLFVSAANLLGRTKTLKVGTMGVVVPT
AHPVRQAEDVLLLDQLSKGRFNFGVVRGLYHKDFRVFGVNMEESREITQDFHQMIMKSFDEGAIHSNSKHIDFPDVNVYP
TKYSKEIRTCMTAESASTTEWLARQGMPMVLSWIIGTNEKKTQMELYNEIATEHGHDISKIDHCLTYICSVHEDGDRARE
VCRKFLISFYDSYVNATNIFNDSDQTRGYDYHKGQWRDFVLQGHTDTNRRVDYSHGLNPVGTPAECLEIIQRDIDATGIT
NVTCGFEANGTEEEIIASMELFMTKVAPFLKEPQK

Specific function: Light-emitting reaction in luminous bacteria [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial luciferase oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018235
- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR002103 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.14.14.3 [H]

Molecular weight: Translated: 40547; Mature: 40547

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00494 BACTERIAL_LUCIFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGNIYFSYQPPGETHKQIMDRFVRLGSVSEELGFDTYWTLEHHFTEFGLTGSLFVSAA
CCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEHHHHHHHHCCCHHHHHHHH
NLLGRTKTLKVGTMGVVVPTAHPVRQAEDVLLLDQLSKGRFNFGVVRGLYHKDFRVFGVN
HHHCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECC
MEESREITQDFHQMIMKSFDEGAIHSNSKHIDFPDVNVYPTKYSKEIRTCMTAESASTTE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHH
WLARQGMPMVLSWIIGTNEKKTQMELYNEIATEHGHDISKIDHCLTYICSVHEDGDRARE
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHH
VCRKFLISFYDSYVNATNIFNDSDQTRGYDYHKGQWRDFVLQGHTDTNRRVDYSHGLNPV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEHHCCCCCC
GTPAECLEIIQRDIDATGITNVTCGFEANGTEEEIIASMELFMTKVAPFLKEPQK
CCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFGNIYFSYQPPGETHKQIMDRFVRLGSVSEELGFDTYWTLEHHFTEFGLTGSLFVSAA
CCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCEEEEHHHHHHHHCCCHHHHHHHH
NLLGRTKTLKVGTMGVVVPTAHPVRQAEDVLLLDQLSKGRFNFGVVRGLYHKDFRVFGVN
HHHCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECC
MEESREITQDFHQMIMKSFDEGAIHSNSKHIDFPDVNVYPTKYSKEIRTCMTAESASTTE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHH
WLARQGMPMVLSWIIGTNEKKTQMELYNEIATEHGHDISKIDHCLTYICSVHEDGDRARE
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHH
VCRKFLISFYDSYVNATNIFNDSDQTRGYDYHKGQWRDFVLQGHTDTNRRVDYSHGLNPV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEHHCCCCCC
GTPAECLEIIQRDIDATGITNVTCGFEANGTEEEIIASMELFMTKVAPFLKEPQK
CCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3340562 [H]