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The map label for this gene is ytfL [C]

Identifier: 59714097

GI number: 59714097

Start: 1038152

End: 1039396

Strand: Reverse

Name: ytfL [C]

Synonym: VF_A0914

Alternate gene names: 59714097

Gene position: 1039396-1038152 (Counterclockwise)

Preceding gene: 59714098

Following gene: 172087821

Centisome position: 78.13

GC content: 39.68

Gene sequence:

>1245_bases
ATGTCTGAGATTGCTCTCATGACCGCAAAAAAGAGTCGATTACAGAAATTAGCAGCAGAAGGCAGTAAGTCAGCTGCTAA
AGCGATTAAATTAGGCGAAGAGCCTACTCAGTTCTTATCTACCGTACAGATAGGTATTACCGGTATTGGTATCTTAAATG
GTATCTTAGGTGAGGCGGCATTTTCAGGCCCGATCTCAAATTTCCTTATTTCATTCGGTGTACCAGCAGGATTAGCGTCT
ACCGTTTCGACTATGTCGACTGTTGTGATCATCACCTATGTCTCAATTGTTGTTGGTGAGCTTGTTCCAAAACGTATAGC
ACAATTTCACGCAGAACGTATTGCAACGCTTATAGCGCCATTGATCAGCATGTTAGCTTCTGTTTCTCGACCATTTGTAT
TCTTACTATCGATCTCAACAGATGCGATTTTACGTTTATTAGGTCGCTCAAACAGCGATGAAGCATCGATTACTGAAGAT
GATATTCACGCTTTGCTTTCAGAAGGCTCTGAGCAAGGTGTTATTGAAAAGCATGAGCATAGTATGGTGCGCAATATCTT
GCAATTAGATGATAGACGAGTTGCATCACTCATGATCCCACGAAATGAATTGGTTTATTTCGACACCGAGCAATCGTGGG
ATGAGAACTTACCAAAATTATTGCGCTCAGAATATTCTATTTACCCTGTAACACGTGGTGGAATGGATAATGTTCTTGGA
TTTACAACATCACGATTTTTACTAAAAGCAGCGCATCAAGAACATCGAACCAAATGGTTAATGCGTAATTTATTACCTTG
TTTAACGATTTTAGAAACAAAATACGGCAGTGAATTGTTGGAGTTGCTAAAAACGACGGGTGAAGAGATTGCTTTAGTGG
TAGATGAGTATGGTGATGCTCAAGGTATTGTAACGCAAAAGAATTTGCTAGAAGCGTTAGCGGGTGAGTTTAAATCTGAA
AACCCAAATGATGCATGGGCTGATCAAGTATCAGAAACGGAATGGGTTTTAGACGGTTCTATTCCGACAACAGTGCTAAA
AGATACTTTAAATCTGGCGACCTTACCTGAAGAGAAAGAAGGGGATTACCAAACACTGACAGGAATGTTTATGTGGCTAA
CAAGCAATGTACCTGCTGTTGGAGATACCTTAGAGTATCAAGACTGGAGTTTTGAAGTATTATCTATTGATAATAATAAA
GCGAATAAAGTTCGAGTTACTCAAGTTCAGTCTGAATTGGTTTAG

Upstream 100 bases:

>100_bases
TAATAACGTATGTACGTTGTTTTTATTACTTAATAATTCGAGGTTTACATTGGATATTGCCATATTACTTTTTCTAATTG
TGATTAATGGTGTGTTTGCT

Downstream 100 bases:

>100_bases
AAATCATAGAATAATAAATAAAAGGAGATCATATGATCTCCTTTTATTTATTATTTTTTAATCAACCAACTTGGGTTTAA
TGATTGCCACGAGATTTCTG

Product: inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSEIALMTAKKSRLQKLAAEGSKSAAKAIKLGEEPTQFLSTVQIGITGIGILNGILGEAAFSGPISNFLISFGVPAGLAS
TVSTMSTVVIITYVSIVVGELVPKRIAQFHAERIATLIAPLISMLASVSRPFVFLLSISTDAILRLLGRSNSDEASITED
DIHALLSEGSEQGVIEKHEHSMVRNILQLDDRRVASLMIPRNELVYFDTEQSWDENLPKLLRSEYSIYPVTRGGMDNVLG
FTTSRFLLKAAHQEHRTKWLMRNLLPCLTILETKYGSELLELLKTTGEEIALVVDEYGDAQGIVTQKNLLEALAGEFKSE
NPNDAWADQVSETEWVLDGSIPTTVLKDTLNLATLPEEKEGDYQTLTGMFMWLTSNVPAVGDTLEYQDWSFEVLSIDNNK
ANKVRVTQVQSELV

Sequences:

>Translated_414_residues
MSEIALMTAKKSRLQKLAAEGSKSAAKAIKLGEEPTQFLSTVQIGITGIGILNGILGEAAFSGPISNFLISFGVPAGLAS
TVSTMSTVVIITYVSIVVGELVPKRIAQFHAERIATLIAPLISMLASVSRPFVFLLSISTDAILRLLGRSNSDEASITED
DIHALLSEGSEQGVIEKHEHSMVRNILQLDDRRVASLMIPRNELVYFDTEQSWDENLPKLLRSEYSIYPVTRGGMDNVLG
FTTSRFLLKAAHQEHRTKWLMRNLLPCLTILETKYGSELLELLKTTGEEIALVVDEYGDAQGIVTQKNLLEALAGEFKSE
NPNDAWADQVSETEWVLDGSIPTTVLKDTLNLATLPEEKEGDYQTLTGMFMWLTSNVPAVGDTLEYQDWSFEVLSIDNNK
ANKVRVTQVQSELV
>Mature_413_residues
SEIALMTAKKSRLQKLAAEGSKSAAKAIKLGEEPTQFLSTVQIGITGIGILNGILGEAAFSGPISNFLISFGVPAGLAST
VSTMSTVVIITYVSIVVGELVPKRIAQFHAERIATLIAPLISMLASVSRPFVFLLSISTDAILRLLGRSNSDEASITEDD
IHALLSEGSEQGVIEKHEHSMVRNILQLDDRRVASLMIPRNELVYFDTEQSWDENLPKLLRSEYSIYPVTRGGMDNVLGF
TTSRFLLKAAHQEHRTKWLMRNLLPCLTILETKYGSELLELLKTTGEEIALVVDEYGDAQGIVTQKNLLEALAGEFKSEN
PNDAWADQVSETEWVLDGSIPTTVLKDTLNLATLPEEKEGDYQTLTGMFMWLTSNVPAVGDTLEYQDWSFEVLSIDNNKA
NKVRVTQVQSELV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=27.6315789473684, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1790664, Length=416, Percent_Identity=29.8076923076923, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI145693175, Length=416, Percent_Identity=24.7596153846154, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788119, Length=277, Percent_Identity=27.0758122743682, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082033, Length=280, Percent_Identity=26.4285714285714, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786879, Length=251, Percent_Identity=23.5059760956175, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 45549; Mature: 45417

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIALMTAKKSRLQKLAAEGSKSAAKAIKLGEEPTQFLSTVQIGITGIGILNGILGEAA
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGPISNFLISFGVPAGLASTVSTMSTVVIITYVSIVVGELVPKRIAQFHAERIATLIAP
HCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISMLASVSRPFVFLLSISTDAILRLLGRSNSDEASITEDDIHALLSEGSEQGVIEKHEH
HHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
SMVRNILQLDDRRVASLMIPRNELVYFDTEQSWDENLPKLLRSEYSIYPVTRGGMDNVLG
HHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHH
FTTSRFLLKAAHQEHRTKWLMRNLLPCLTILETKYGSELLELLKTTGEEIALVVDEYGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
QGIVTQKNLLEALAGEFKSENPNDAWADQVSETEWVLDGSIPTTVLKDTLNLATLPEEKE
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCCC
GDYQTLTGMFMWLTSNVPAVGDTLEYQDWSFEVLSIDNNKANKVRVTQVQSELV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHCC
>Mature Secondary Structure 
SEIALMTAKKSRLQKLAAEGSKSAAKAIKLGEEPTQFLSTVQIGITGIGILNGILGEAA
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGPISNFLISFGVPAGLASTVSTMSTVVIITYVSIVVGELVPKRIAQFHAERIATLIAP
HCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISMLASVSRPFVFLLSISTDAILRLLGRSNSDEASITEDDIHALLSEGSEQGVIEKHEH
HHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
SMVRNILQLDDRRVASLMIPRNELVYFDTEQSWDENLPKLLRSEYSIYPVTRGGMDNVLG
HHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHH
FTTSRFLLKAAHQEHRTKWLMRNLLPCLTILETKYGSELLELLKTTGEEIALVVDEYGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
QGIVTQKNLLEALAGEFKSENPNDAWADQVSETEWVLDGSIPTTVLKDTLNLATLPEEKE
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCCC
GDYQTLTGMFMWLTSNVPAVGDTLEYQDWSFEVLSIDNNKANKVRVTQVQSELV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]