Click here to switch to the map view.

The map label for this gene is yghU [H]

Identifier: 59714032

GI number: 59714032

Start: 958565

End: 959425

Strand: Reverse

Name: yghU [H]

Synonym: VF_A0849

Alternate gene names: 59714032

Gene position: 959425-958565 (Counterclockwise)

Preceding gene: 59714034

Following gene: 59714030

Centisome position: 72.12

GC content: 40.42

Gene sequence:

>861_bases
ATGAATAATCAATATGTACCCCCAAAAGTTTGGACATCAGAAACGGACAGCAGCGGTCAATGGGCGAGCATTAATCGACC
ATACTCAGGGGCAAGGCATGAGCGAGAATTGCCTATTGGTGAACATACTTTACAGCTGTACTCTTTAGCGACACCAAATG
GGCAAAAAGTAACGATTCTATTGGAAGAATTGCTCGCATTAGGGATTAAAGAGGCCGAATATGACGCATATTTAATTAAT
ATTGGGGAGGGAGATCAATTTGCATCTGGTTTTGTTGATATTAACCCAAACTCAAAGATCCCTGCGTTAGTTGATCATTC
TGTTGATCCTGAACTTCATGTATTTGAATCTGGCGCAATTTTATTATATTTGGCTGATAAGTTTGGCCATTTTATTCCTA
AAGAGCTCTCTGCTCGTACTCAAGTATTAAATTGGTTATTTTGGCTTCAGGGCTCAGCTCCATATTTAGGTGGTGGTTTT
GGTCACTTTTATGTGTATGCGCCAGAAAAATATGAATATCCCATTAATCGGTTCTCAATGGAGGCAAAACGCCAATTAGA
TGTGCTTGATAAGCAGCTTGCTACCACCAAATACATTGCTGGTAATGAATATAGTATTGCTGATATGGCTATTTGGCCTT
GGTATGGCAATCTAGTATTAGGGAATTTATATGATGCAGCAGAGTTTTTAGATGTTGAAAGCTATGTGCATGTTCTTGAA
TGGGCAAAAGAGATAGCGCAACGAAAAGGGGTTCAACGTGGACGTATCGTAAACCGTTCATGGGGCGAACCATGGGAGCA
AGTGCCAGAACGCCACAGTGCAGAAGATATTGATCTTATTTTGGATCTACAGCCTAAGTAA

Upstream 100 bases:

>100_bases
TGTTTTGGCTATTTTTTCCGTATAGCGAATACATGGTTTTTTAGAAGTGGTCTATAGTAATAATGTGTAAATATTGAGGA
TGAATGAGTAAGGAGCGAGT

Downstream 100 bases:

>100_bases
ATCACGTTTTTTTTACGTTTTAATACAAAAGGCGACATTATTATATTGTCGCCTTTGTTGTTTTATCTATTCGCATTTTC
AGATTTAGTTTAGCTAGCTA

Product: putative glutathione S-transferase YghU

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNNQYVPPKVWTSETDSSGQWASINRPYSGARHERELPIGEHTLQLYSLATPNGQKVTILLEELLALGIKEAEYDAYLIN
IGEGDQFASGFVDINPNSKIPALVDHSVDPELHVFESGAILLYLADKFGHFIPKELSARTQVLNWLFWLQGSAPYLGGGF
GHFYVYAPEKYEYPINRFSMEAKRQLDVLDKQLATTKYIAGNEYSIADMAIWPWYGNLVLGNLYDAAEFLDVESYVHVLE
WAKEIAQRKGVQRGRIVNRSWGEPWEQVPERHSAEDIDLILDLQPK

Sequences:

>Translated_286_residues
MNNQYVPPKVWTSETDSSGQWASINRPYSGARHERELPIGEHTLQLYSLATPNGQKVTILLEELLALGIKEAEYDAYLIN
IGEGDQFASGFVDINPNSKIPALVDHSVDPELHVFESGAILLYLADKFGHFIPKELSARTQVLNWLFWLQGSAPYLGGGF
GHFYVYAPEKYEYPINRFSMEAKRQLDVLDKQLATTKYIAGNEYSIADMAIWPWYGNLVLGNLYDAAEFLDVESYVHVLE
WAKEIAQRKGVQRGRIVNRSWGEPWEQVPERHSAEDIDLILDLQPK
>Mature_286_residues
MNNQYVPPKVWTSETDSSGQWASINRPYSGARHERELPIGEHTLQLYSLATPNGQKVTILLEELLALGIKEAEYDAYLIN
IGEGDQFASGFVDINPNSKIPALVDHSVDPELHVFESGAILLYLADKFGHFIPKELSARTQVLNWLFWLQGSAPYLGGGF
GHFYVYAPEKYEYPINRFSMEAKRQLDVLDKQLATTKYIAGNEYSIADMAIWPWYGNLVLGNLYDAAEFLDVESYVHVLE
WAKEIAQRKGVQRGRIVNRSWGEPWEQVPERHSAEDIDLILDLQPK

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87082195, Length=277, Percent_Identity=67.5090252707581, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1788640, Length=208, Percent_Identity=39.4230769230769, Blast_Score=141, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324100, Length=256, Percent_Identity=27.34375, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864592, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571670, Length=203, Percent_Identity=26.6009852216749, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 32532; Mature: 32532

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQYVPPKVWTSETDSSGQWASINRPYSGARHERELPIGEHTLQLYSLATPNGQKVTIL
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHEEEEEEEECCCCCEEEHH
LEELLALGIKEAEYDAYLINIGEGDQFASGFVDINPNSKIPALVDHSVDPELHVFESGAI
HHHHHHCCCCCCCCCEEEEECCCCCCHHCCEEEECCCCCCCEEECCCCCCCEEEEECCEE
LLYLADKFGHFIPKELSARTQVLNWLFWLQGSAPYLGGGFGHFYVYAPEKYEYPINRFSM
EEEEECHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHH
EAKRQLDVLDKQLATTKYIAGNEYSIADMAIWPWYGNLVLGNLYDAAEFLDVESYVHVLE
HHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHH
WAKEIAQRKGVQRGRIVNRSWGEPWEQVPERHSAEDIDLILDLQPK
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MNNQYVPPKVWTSETDSSGQWASINRPYSGARHERELPIGEHTLQLYSLATPNGQKVTIL
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHEEEEEEEECCCCCEEEHH
LEELLALGIKEAEYDAYLINIGEGDQFASGFVDINPNSKIPALVDHSVDPELHVFESGAI
HHHHHHCCCCCCCCCEEEEECCCCCCHHCCEEEECCCCCCCEEECCCCCCCEEEEECCEE
LLYLADKFGHFIPKELSARTQVLNWLFWLQGSAPYLGGGFGHFYVYAPEKYEYPINRFSM
EEEEECHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHHHHH
EAKRQLDVLDKQLATTKYIAGNEYSIADMAIWPWYGNLVLGNLYDAAEFLDVESYVHVLE
HHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHH
WAKEIAQRKGVQRGRIVNRSWGEPWEQVPERHSAEDIDLILDLQPK
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]