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The map label for this gene is catB2 [H]

Identifier: 59713973

GI number: 59713973

Start: 886006

End: 886662

Strand: Reverse

Name: catB2 [H]

Synonym: VF_A0790

Alternate gene names: 59713973

Gene position: 886662-886006 (Counterclockwise)

Preceding gene: 59713975

Following gene: 59713972

Centisome position: 66.65

GC content: 38.51

Gene sequence:

>657_bases
ATGGAAGCGTTTAATAGTTGGCTTGAAGGTCAAAACCTCAAAGAACAGGTTAAGAACCCAAATATTGAAGTTGGAGATTA
TAGCTATTATTCAGGTTTTTATCACTCTAAGACCTTTGAGGAGCAAGCTGTTCGTTACTTATTAGGAGATGCTCCTACAC
AAGAAGTGTGGGAGAGCGGACAGTTTGGAGAGGTTGATAAACTCCGAATAGGTAAATTTTGCTCTATTGCATCAGGGGCA
ACATTTATGATGGCTGGCAATCAAGGACATAGAGCCGATTGGATATCAACATTTCCATTTTCAAAAAAAGAGTTTGGCGA
AGGTGTGAAAGATGGCTTTCAAAGAGCTGGCGATACCATTGTGGGTAACGATGTATGGATTGGTAGTGAGGCAATGATTA
TGCCTGGCGTTCATATTGGAGATGGTGCAATCATTGGAGCTAGAGCCGTTATTACTAAAAATGTGGCACCTTATTCCGTT
GTGGTAGGAAATAATGTGGTGGTTAAAAAACGATTTGATGAAAATTTAATTCAAACATTATTAGTCATAAAGTGGTGGGA
TTGGCCACTGCAACACATTAAAAATACAATGGAGATCCTATGTAGTGGGCATATTGAAGAATTAGAGCAGTATTTTATAA
AGAATGTAGGCTCTTAA

Upstream 100 bases:

>100_bases
TTTATTTCCATATGGTAATTCTGTTTATCTAAATGGTCTCTACTGGAAATAATAGAGACTGATTATACTTTCAGCAAGAT
TAATTTAAGAGAAAGAATAA

Downstream 100 bases:

>100_bases
TTGATATTAGTTTAAAGGCTCTGACTTAGGTTGAGCCTTTTACTTTTGTTATAACAATAAATTATCAAAATAATAAATAT
CGATAATTTCATATTATCAA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MEAFNSWLEGQNLKEQVKNPNIEVGDYSYYSGFYHSKTFEEQAVRYLLGDAPTQEVWESGQFGEVDKLRIGKFCSIASGA
TFMMAGNQGHRADWISTFPFSKKEFGEGVKDGFQRAGDTIVGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNVAPYSV
VVGNNVVVKKRFDENLIQTLLVIKWWDWPLQHIKNTMEILCSGHIEELEQYFIKNVGS

Sequences:

>Translated_218_residues
MEAFNSWLEGQNLKEQVKNPNIEVGDYSYYSGFYHSKTFEEQAVRYLLGDAPTQEVWESGQFGEVDKLRIGKFCSIASGA
TFMMAGNQGHRADWISTFPFSKKEFGEGVKDGFQRAGDTIVGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNVAPYSV
VVGNNVVVKKRFDENLIQTLLVIKWWDWPLQHIKNTMEILCSGHIEELEQYFIKNVGS
>Mature_218_residues
MEAFNSWLEGQNLKEQVKNPNIEVGDYSYYSGFYHSKTFEEQAVRYLLGDAPTQEVWESGQFGEVDKLRIGKFCSIASGA
TFMMAGNQGHRADWISTFPFSKKEFGEGVKDGFQRAGDTIVGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNVAPYSV
VVGNNVVVKKRFDENLIQTLLVIKWWDWPLQHIKNTMEILCSGHIEELEQYFIKNVGS

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24449; Mature: 24449

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAFNSWLEGQNLKEQVKNPNIEVGDYSYYSGFYHSKTFEEQAVRYLLGDAPTQEVWESG
CCHHHHHHCCCCHHHHHCCCCEEECCCHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCC
QFGEVDKLRIGKFCSIASGATFMMAGNQGHRADWISTFPFSKKEFGEGVKDGFQRAGDTI
CCCCHHHHHHCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCEE
VGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNVAPYSVVVGNNVVVKKRFDENLIQTL
ECCCEEECCCEEEECCEEECCCCEECHHHHEECCCCCEEEEECCCEEEEEHHHHHHHHHH
LVIKWWDWPLQHIKNTMEILCSGHIEELEQYFIKNVGS
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MEAFNSWLEGQNLKEQVKNPNIEVGDYSYYSGFYHSKTFEEQAVRYLLGDAPTQEVWESG
CCHHHHHHCCCCHHHHHCCCCEEECCCHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCC
QFGEVDKLRIGKFCSIASGATFMMAGNQGHRADWISTFPFSKKEFGEGVKDGFQRAGDTI
CCCCHHHHHHCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCEE
VGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNVAPYSVVVGNNVVVKKRFDENLIQTL
ECCCEEECCCEEEECCEEECCCCEECHHHHEECCCCCEEEEECCCEEEEEHHHHHHHHHH
LVIKWWDWPLQHIKNTMEILCSGHIEELEQYFIKNVGS
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]