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The map label for this gene is hlyB [H]

Identifier: 59713860

GI number: 59713860

Start: 747434

End: 749347

Strand: Reverse

Name: hlyB [H]

Synonym: VF_A0677

Alternate gene names: 59713860

Gene position: 749347-747434 (Counterclockwise)

Preceding gene: 59713867

Following gene: 59713858

Centisome position: 56.33

GC content: 40.28

Gene sequence:

>1914_bases
ATGATTAATCTAACAATAAAACAGAAACTCGTCGCCGGTATCGTTATCGCTATCATTGCTTCAACTTCTCTTGTGGGTAT
TGTCGCCCAAAAAAAAGCGTATGAAACTTTAGATGAAAGGCTAACCACGCTTGAGCTTCCTACTATTCTTGACCGAATTG
GTGGAGAAGTAGATAAAGAGGTGGCAGTACTTTCTGCTGCTGCTGAGCAAATGTCTAATAACCCTTTCATTATCGATGCT
ATTTCTGATTCTTACACCTCTCCTGAAGACCAAAATGTTCTTATTGGTCAATTAAATAAACTAAAACAACAACATAATCT
GAATGATGCATCCGTTGCTAACCGTCAAACAGCAAATTATTGGAATCAGGATGGCTTTTTACGTCAACTAAACAAACAAC
AAGACGGTTGGTTTTTTGGGTTCACACAAAGTGGCCCTGAGCGTATGTTGAATGTATTTACTGAGCAAAACGGTGAAGTA
AAACTGTTTGTTAATTTCCAACAGCTAAATGGCGTTTCAATGGCCGGTTTATCTAAATCATTAGATGATATGGTTGCTTT
GTTAAATGGATTTAGAATTGAACAAACGGGTTTTGTTTATTTAATGGATGGTGACGGTAATATCAAAATCCATAAAAACA
AAGCGATTATGGGCAAGCAAACCATTAAAGATGTGGTTGGTTCTGCTGAAGCATCGGTATTACTGACAAAGAAAAACTTC
AATCTAAGCCGCATGGAAAAAGGTGGCCAAGAGATCTTTATCGCTTCGCATTACATTCCTTCAATGGAGTGGTTTATTGT
TGCTGAAGTACCGGTTTCTGAAGTGTTTGAAAGTTTGCATGCCTCTACCCAAGACATCATTATGTGGATTGTGGTTATTA
TTGCGGTATTTGTCTCTTTAGCTATTTGGGGCGCAGGCTCAATCACTAATAAACTGAACGAACTTGCACATCGCTTTAAA
GAGCTAGGTGAGGGGGAAGGTGACTTAACGCATCGTATCGAAGTGAAAGGTAATGATGAAATTACGGAACTTTCAAAAGG
CTTTAATAGTTTTGTCGAGAAAATTCACAATACGGTTTCTGAAGTGGTTGAAACTGGCCATGTATTACACACTACGGCTG
AAAATGTAGCGTTAAAAGCAACATCAACACGTGATAACAGTGAAATGCAGCGTGACCAAACGCTTCAAGTCGTAACGGCT
ATTAACCAAATGGGTAGTACGATTAACGAAATTGCATCCAATGCGGCGAATGCAGCACAATCAGCAAGTAAAGCTGAAGC
AAGTACTCAAGATGGTCGTCAAACTGTGATTGACTCTCGTGACGCAATTACCCAACTTGAAGGTGATTTAGTTCAAGTGA
GCCATGTGGTGGAGCAATTAGCGGGTACAACACAAGACATTGGCTCTATCCTTGACGTTATTCGTGGTATTTCAGAGCAA
ACCAATTTACTTGCGTTAAATGCAGCCATTGAAGCCGCTCGTGCTGGTGATCATGGTCGTGGTTTTGCTGTGGTTGCAGA
TGAAGTTCGTCAATTAGCAAGCCGTACATCAGAATCAACGGATGAAATCCAGAAGATGATTGATCAACTGCAAAACGAAG
CGAAAAATGCGGTGGATGCGATGGAAGCAAGTCACAGTGTAACGGCTCGTGGTGTTGAATCCGCAGACAGTGCAACACAA
GTGTTAGCGGGTATTGCAAAAAGTATCACAGATATTTCTGATATGAATACGCAAGTGGCAACGGCAACAGAAGAGCAATC
TACTGTGGTTTATACGATTAACCAAAATATCGAAGAGATTAATGGTATTAATGAGTTAACCACCGCCACAGCACAAGAGC
TTGCTGATTCAAGTCAGCAATTGAATGCACTTTCACAGCGATTGGATCAATTAGTTGGTGCTTTTAAAGTCTAA

Upstream 100 bases:

>100_bases
TATTCAACTATTTAATTAATGAATGTTTTTCTAATTATTTATTAAAGTTATGAAATGTGCGGTCGTTATATGAAGGGTCT
ATTTTAGCTGTGGAAAAATT

Downstream 100 bases:

>100_bases
CTGACGGCTTTAGGTTTACCTTTTGAGGGGTTCTCTTGTGGAACCCCGAAACAGTTTTACTTGCAGTATTCATTTTTCAT
ATTGTTCATACTAATCCATA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MINLTIKQKLVAGIVIAIIASTSLVGIVAQKKAYETLDERLTTLELPTILDRIGGEVDKEVAVLSAAAEQMSNNPFIIDA
ISDSYTSPEDQNVLIGQLNKLKQQHNLNDASVANRQTANYWNQDGFLRQLNKQQDGWFFGFTQSGPERMLNVFTEQNGEV
KLFVNFQQLNGVSMAGLSKSLDDMVALLNGFRIEQTGFVYLMDGDGNIKIHKNKAIMGKQTIKDVVGSAEASVLLTKKNF
NLSRMEKGGQEIFIASHYIPSMEWFIVAEVPVSEVFESLHASTQDIIMWIVVIIAVFVSLAIWGAGSITNKLNELAHRFK
ELGEGEGDLTHRIEVKGNDEITELSKGFNSFVEKIHNTVSEVVETGHVLHTTAENVALKATSTRDNSEMQRDQTLQVVTA
INQMGSTINEIASNAANAAQSASKAEASTQDGRQTVIDSRDAITQLEGDLVQVSHVVEQLAGTTQDIGSILDVIRGISEQ
TNLLALNAAIEAARAGDHGRGFAVVADEVRQLASRTSESTDEIQKMIDQLQNEAKNAVDAMEASHSVTARGVESADSATQ
VLAGIAKSITDISDMNTQVATATEEQSTVVYTINQNIEEINGINELTTATAQELADSSQQLNALSQRLDQLVGAFKV

Sequences:

>Translated_637_residues
MINLTIKQKLVAGIVIAIIASTSLVGIVAQKKAYETLDERLTTLELPTILDRIGGEVDKEVAVLSAAAEQMSNNPFIIDA
ISDSYTSPEDQNVLIGQLNKLKQQHNLNDASVANRQTANYWNQDGFLRQLNKQQDGWFFGFTQSGPERMLNVFTEQNGEV
KLFVNFQQLNGVSMAGLSKSLDDMVALLNGFRIEQTGFVYLMDGDGNIKIHKNKAIMGKQTIKDVVGSAEASVLLTKKNF
NLSRMEKGGQEIFIASHYIPSMEWFIVAEVPVSEVFESLHASTQDIIMWIVVIIAVFVSLAIWGAGSITNKLNELAHRFK
ELGEGEGDLTHRIEVKGNDEITELSKGFNSFVEKIHNTVSEVVETGHVLHTTAENVALKATSTRDNSEMQRDQTLQVVTA
INQMGSTINEIASNAANAAQSASKAEASTQDGRQTVIDSRDAITQLEGDLVQVSHVVEQLAGTTQDIGSILDVIRGISEQ
TNLLALNAAIEAARAGDHGRGFAVVADEVRQLASRTSESTDEIQKMIDQLQNEAKNAVDAMEASHSVTARGVESADSATQ
VLAGIAKSITDISDMNTQVATATEEQSTVVYTINQNIEEINGINELTTATAQELADSSQQLNALSQRLDQLVGAFKV
>Mature_637_residues
MINLTIKQKLVAGIVIAIIASTSLVGIVAQKKAYETLDERLTTLELPTILDRIGGEVDKEVAVLSAAAEQMSNNPFIIDA
ISDSYTSPEDQNVLIGQLNKLKQQHNLNDASVANRQTANYWNQDGFLRQLNKQQDGWFFGFTQSGPERMLNVFTEQNGEV
KLFVNFQQLNGVSMAGLSKSLDDMVALLNGFRIEQTGFVYLMDGDGNIKIHKNKAIMGKQTIKDVVGSAEASVLLTKKNF
NLSRMEKGGQEIFIASHYIPSMEWFIVAEVPVSEVFESLHASTQDIIMWIVVIIAVFVSLAIWGAGSITNKLNELAHRFK
ELGEGEGDLTHRIEVKGNDEITELSKGFNSFVEKIHNTVSEVVETGHVLHTTAENVALKATSTRDNSEMQRDQTLQVVTA
INQMGSTINEIASNAANAAQSASKAEASTQDGRQTVIDSRDAITQLEGDLVQVSHVVEQLAGTTQDIGSILDVIRGISEQ
TNLLALNAAIEAARAGDHGRGFAVVADEVRQLASRTSESTDEIQKMIDQLQNEAKNAVDAMEASHSVTARGVESADSATQ
VLAGIAKSITDISDMNTQVATATEEQSTVVYTINQNIEEINGINELTTATAQELADSSQQLNALSQRLDQLVGAFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=384, Percent_Identity=27.34375, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI2367378, Length=355, Percent_Identity=29.0140845070423, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788195, Length=311, Percent_Identity=29.903536977492, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=27.6276276276276, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789453, Length=375, Percent_Identity=25.6, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69194; Mature: 69194

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLTIKQKLVAGIVIAIIASTSLVGIVAQKKAYETLDERLTTLELPTILDRIGGEVDKE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VAVLSAAAEQMSNNPFIIDAISDSYTSPEDQNVLIGQLNKLKQQHNLNDASVANRQTANY
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCHHCC
WNQDGFLRQLNKQQDGWFFGFTQSGPERMLNVFTEQNGEVKLFVNFQQLNGVSMAGLSKS
CCCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEEHHHHCCCCHHHHHHH
LDDMVALLNGFRIEQTGFVYLMDGDGNIKIHKNKAIMGKQTIKDVVGSAEASVLLTKKNF
HHHHHHHHCCCEEECCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCC
NLSRMEKGGQEIFIASHYIPSMEWFIVAEVPVSEVFESLHASTQDIIMWIVVIIAVFVSL
CHHHHHCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIWGAGSITNKLNELAHRFKELGEGEGDLTHRIEVKGNDEITELSKGFNSFVEKIHNTVS
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
EVVETGHVLHTTAENVALKATSTRDNSEMQRDQTLQVVTAINQMGSTINEIASNAANAAQ
HHHHCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SASKAEASTQDGRQTVIDSRDAITQLEGDLVQVSHVVEQLAGTTQDIGSILDVIRGISEQ
HHHHHHCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
TNLLALNAAIEAARAGDHGRGFAVVADEVRQLASRTSESTDEIQKMIDQLQNEAKNAVDA
CCEEEEHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
MEASHSVTARGVESADSATQVLAGIAKSITDISDMNTQVATATEEQSTVVYTINQNIEEI
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCEEEEEECCCHHHH
NGINELTTATAQELADSSQQLNALSQRLDQLVGAFKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINLTIKQKLVAGIVIAIIASTSLVGIVAQKKAYETLDERLTTLELPTILDRIGGEVDKE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VAVLSAAAEQMSNNPFIIDAISDSYTSPEDQNVLIGQLNKLKQQHNLNDASVANRQTANY
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCHHCC
WNQDGFLRQLNKQQDGWFFGFTQSGPERMLNVFTEQNGEVKLFVNFQQLNGVSMAGLSKS
CCCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEEHHHHCCCCHHHHHHH
LDDMVALLNGFRIEQTGFVYLMDGDGNIKIHKNKAIMGKQTIKDVVGSAEASVLLTKKNF
HHHHHHHHCCCEEECCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCC
NLSRMEKGGQEIFIASHYIPSMEWFIVAEVPVSEVFESLHASTQDIIMWIVVIIAVFVSL
CHHHHHCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIWGAGSITNKLNELAHRFKELGEGEGDLTHRIEVKGNDEITELSKGFNSFVEKIHNTVS
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
EVVETGHVLHTTAENVALKATSTRDNSEMQRDQTLQVVTAINQMGSTINEIASNAANAAQ
HHHHCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SASKAEASTQDGRQTVIDSRDAITQLEGDLVQVSHVVEQLAGTTQDIGSILDVIRGISEQ
HHHHHHCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
TNLLALNAAIEAARAGDHGRGFAVVADEVRQLASRTSESTDEIQKMIDQLQNEAKNAVDA
CCEEEEHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
MEASHSVTARGVESADSATQVLAGIAKSITDISDMNTQVATATEEQSTVVYTINQNIEEI
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCEEEEEECCCHHHH
NGINELTTATAQELADSSQQLNALSQRLDQLVGAFKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]