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The map label for this gene is rbgA [H]

Identifier: 59713694

GI number: 59713694

Start: 587574

End: 588518

Strand: Reverse

Name: rbgA [H]

Synonym: VF_A0511

Alternate gene names: 59713694

Gene position: 588518-587574 (Counterclockwise)

Preceding gene: 59713697

Following gene: 59713692

Centisome position: 44.24

GC content: 40.32

Gene sequence:

>945_bases
ATGCTTAACAATAAAATTCAATGGTTCCCGGGACACATGCACAAAGCTCGTAAAGAGATTGAAGAAGTTGTGCCAAAAAT
CGATGTTATCATTGAAGTTCTTGACGCCCGTATTCCTTTTAGTAGTGAAAATCCGCTTATCTCTTCTATTCGTAAAGACA
AGCCGTGTGTAAAAGTACTCAATAAGCGTGATTTATCGGATCCAGAAGTGACTCAACTTTGGATTGAGCATTTAGAAAAA
GAGCAAGGCGTAACTGCAATGGCGGTTACTACGGAAAATCCAGAAGAAATTCATAAGATCATGGAAGTATGTCGTAAGCT
TGTTCCTCACAGAGAGGCAATGGGCAAAAACGTTCGTACTATGATCATGGGTATTCCTAATGTTGGGAAATCAACCATCA
TTAATACTTTAGCCGGTCGTACAATTGCTGTAACAGGTAACCAACCAGCGGTTACTCGCCGTCAGCAACGTATTAATCTT
CAAAATGGTGTCGTACTTTCTGATACTCCAGGAATTTTATGGCCAAAAGTTGAAAACCCACACAGTGGATTCCGTCTAGC
GGCAACTGGTGCAGTAAAAGATACAGCAATGGAATATGACGAAGTTGCATTCTACACCGTTGAGTATCTTGCGAAACAAT
ACCCAGAGCGCTTAAAAGAGCGTTACAAATTAGATGAACTACCAGACAATGATTTAGAACTAATGGAAGCGATTGGTCGC
AGCCGTGGTTGTTTACAAGCTGGTGGTCGAATCAACCTTTACAAAGCGTCTGAGATTTTACTTCATGAATTACGTTCAGG
TGTTCTAGGCCAAGTGACTCTTGAATTACCAGAAATGATCACAGAAGAGTTAATTCAAGTTGAAATTGATGCCGCTCGTA
AAGAAGAAGAAAAAGCGAAGAAAAAAGAAGAGCGTCGTAAGCGTTATCTGAAAAACAAACGCTAA

Upstream 100 bases:

>100_bases
TAAGAATAATAATTAACCTATTAAATTTAAGTTTGTTGTTTAGTACCCCATGATGTACCCCAAGCAGCATGCATAAAAAA
ACAAAGAGTATAAAATACAG

Downstream 100 bases:

>100_bases
TATTCCATTACAAAAATGCAAACGGGGAGCTTTACGCTCCCCTTTTTTATTCATACATCAATATCAATTATTCAATGATC
AAACTTAATAAAATCGTTTC

Product: ribosomal biogenesis GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLNNKIQWFPGHMHKARKEIEEVVPKIDVIIEVLDARIPFSSENPLISSIRKDKPCVKVLNKRDLSDPEVTQLWIEHLEK
EQGVTAMAVTTENPEEIHKIMEVCRKLVPHREAMGKNVRTMIMGIPNVGKSTIINTLAGRTIAVTGNQPAVTRRQQRINL
QNGVVLSDTPGILWPKVENPHSGFRLAATGAVKDTAMEYDEVAFYTVEYLAKQYPERLKERYKLDELPDNDLELMEAIGR
SRGCLQAGGRINLYKASEILLHELRSGVLGQVTLELPEMITEELIQVEIDAARKEEEKAKKKEERRKRYLKNKR

Sequences:

>Translated_314_residues
MLNNKIQWFPGHMHKARKEIEEVVPKIDVIIEVLDARIPFSSENPLISSIRKDKPCVKVLNKRDLSDPEVTQLWIEHLEK
EQGVTAMAVTTENPEEIHKIMEVCRKLVPHREAMGKNVRTMIMGIPNVGKSTIINTLAGRTIAVTGNQPAVTRRQQRINL
QNGVVLSDTPGILWPKVENPHSGFRLAATGAVKDTAMEYDEVAFYTVEYLAKQYPERLKERYKLDELPDNDLELMEAIGR
SRGCLQAGGRINLYKASEILLHELRSGVLGQVTLELPEMITEELIQVEIDAARKEEEKAKKKEERRKRYLKNKR
>Mature_314_residues
MLNNKIQWFPGHMHKARKEIEEVVPKIDVIIEVLDARIPFSSENPLISSIRKDKPCVKVLNKRDLSDPEVTQLWIEHLEK
EQGVTAMAVTTENPEEIHKIMEVCRKLVPHREAMGKNVRTMIMGIPNVGKSTIINTLAGRTIAVTGNQPAVTRRQQRINL
QNGVVLSDTPGILWPKVENPHSGFRLAATGAVKDTAMEYDEVAFYTVEYLAKQYPERLKERYKLDELPDNDLELMEAIGR
SRGCLQAGGRINLYKASEILLHELRSGVLGQVTLELPEMITEELIQVEIDAARKEEEKAKKKEERRKRYLKNKR

Specific function: Binds GTP and GDP [H]

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI93277113, Length=294, Percent_Identity=31.9727891156463, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI7019419, Length=262, Percent_Identity=26.7175572519084, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI45593130, Length=285, Percent_Identity=24.9122807017544, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI45643129, Length=285, Percent_Identity=24.9122807017544, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI45643127, Length=285, Percent_Identity=24.9122807017544, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI296317324, Length=189, Percent_Identity=30.6878306878307, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI9506611, Length=189, Percent_Identity=30.6878306878307, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193211047, Length=221, Percent_Identity=31.6742081447964, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563985, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990926, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563983, Length=226, Percent_Identity=29.2035398230088, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534827, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115535155, Length=286, Percent_Identity=25.8741258741259, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25143545, Length=286, Percent_Identity=25.8741258741259, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71982363, Length=186, Percent_Identity=31.1827956989247, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324381, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320842, Length=300, Percent_Identity=28, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323744, Length=221, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI85815858, Length=302, Percent_Identity=30.1324503311258, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI19922460, Length=292, Percent_Identity=26.7123287671233, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28572990, Length=206, Percent_Identity=33.0097087378641, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR019991
- InterPro:   IPR016478
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35861; Mature: 35861

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNKIQWFPGHMHKARKEIEEVVPKIDVIIEVLDARIPFSSENPLISSIRKDKPCVKVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHH
NKRDLSDPEVTQLWIEHLEKEQGVTAMAVTTENPEEIHKIMEVCRKLVPHREAMGKNVRT
HHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHCCCHHH
MIMGIPNVGKSTIINTLAGRTIAVTGNQPAVTRRQQRINLQNGVVLSDTPGILWPKVENP
HEEECCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCEEEECCCCEECCCCCCC
HSGFRLAATGAVKDTAMEYDEVAFYTVEYLAKQYPERLKERYKLDELPDNDLELMEAIGR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
SRGCLQAGGRINLYKASEILLHELRSGVLGQVTLELPEMITEELIQVEIDAARKEEEKAK
CCCHHHCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEERRKRYLKNKR
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLNNKIQWFPGHMHKARKEIEEVVPKIDVIIEVLDARIPFSSENPLISSIRKDKPCVKVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHH
NKRDLSDPEVTQLWIEHLEKEQGVTAMAVTTENPEEIHKIMEVCRKLVPHREAMGKNVRT
HHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHCCCHHH
MIMGIPNVGKSTIINTLAGRTIAVTGNQPAVTRRQQRINLQNGVVLSDTPGILWPKVENP
HEEECCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCEEEECCCCEECCCCCCC
HSGFRLAATGAVKDTAMEYDEVAFYTVEYLAKQYPERLKERYKLDELPDNDLELMEAIGR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
SRGCLQAGGRINLYKASEILLHELRSGVLGQVTLELPEMITEELIQVEIDAARKEEEKAK
CCCHHHCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEERRKRYLKNKR
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]