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The map label for this gene is gltS [H]

Identifier: 59713690

GI number: 59713690

Start: 581905

End: 583128

Strand: Reverse

Name: gltS [H]

Synonym: VF_A0507

Alternate gene names: 59713690

Gene position: 583128-581905 (Counterclockwise)

Preceding gene: 59713691

Following gene: 59713686

Centisome position: 43.83

GC content: 37.09

Gene sequence:

>1224_bases
ATGTCACACACTCTATCTATTGGTGCGCTTGAATCATTTTTAATTGCAATTGCCGTGTTATTCCTCGGCCACTTGATCAA
TTCAAAAGTCGTACTATTCAAAAAATACAATATCCCAGAGCCAATTGTAGGTGGATTAATCGTAGCTTTTTTCATTACGA
TCCTACATTTCCAAGGGATTAACTTAAAGTTCTCACTGCCATTACAAAGCACATTCATGTTGATGTTCTTTAGTACAGTA
GGACTTGCTGCAAACTACAAACAATTAATTAAAGGCGGAAGTAAAGTATTTATCTTCCTTGCTGTAGCTTCTGTTTATAT
CATTATTCAAAATGGTATTGGCGTCAGCCTTGCTAGCTTAATGGGACTTGACCCTCTAATGGGTTTAATCGCAGGTTCAA
TTACACTATCTGGCGGTCATGGTACAGGTGCAGCTTGGTCACATACATTTGCTGAGACATACCATTTAAATACGCTTGAG
CTTGCAATGGCTTCAGCTACATTTGGTTTAATCATGGGTGGATTAATTGGTAGCCCTATCGCACAGAAATTAATTCATAA
GCATAATTTAGAATCAGAATACGGTACTGGCATTGATACACATTCACGCTTCCCTGAAGTTGTTACCTACAATGAACGTG
AAGAAGAAAAAGTAACCGCAAAAAAAGTAATCGAAACATTATTTGTATTACTACTTTGTGTGGTTGGTGCAGGTCATCTT
GGTGACTTTATCGCAACATTTGACATCGCATGGTTAAAAATACCTGATTTTGTATACGCTCTATTCATTGGTGTATTCAT
TACAAATATTACCGAAGTCACTAAAGTACATAAAATCGACACAGAAACTGTCGATATTTTAGGTACCGTTTCATTGGCTC
TGTTTTTAGCAATGGCATTGATGAGTCTTAAGCTGTGGAATATCTTTGATCTAGCGATTCCATTACTTATCATTCTTTCA
ATTCAAACTGTGGTACTTGCTTTATTCTCATACTTTGTAACCTTCAGAGTAATGGGTTCAAATTATGATGCGGCTGTAAT
GGCTGGTGGTCATTGTGGTTTTGGTCTTGGTGCTACACCGACTGCAGTAATGAACATGGGCTCATTAGTTTCTCGCTTCG
GCCCTTCTCCACAAGCATTTATGGTCGTTCCAATTGTTGGTGCTTTCTTTATTGATATTGTAAATTTAATCATTTTACAA
ACTTACATCAGTTTTATCGGATAA

Upstream 100 bases:

>100_bases
GATTAAGAATGCATTAAAATACATGTATTCTTCATTTATTTTCGCATAATTTAAAATTGTGGACGAAACTATAAATTAGA
TATTTCAACTTAGGAGTACT

Downstream 100 bases:

>100_bases
GAAAAAAGCCCTACCTCTCATAGAGTTAGGGCTTTTTTTTATATTAATAGATTAACTTTTAATAACTCAGGCTTTATTGA
CGTTATTAATCGGGATATTC

Product: glutamate transporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSHTLSIGALESFLIAIAVLFLGHLINSKVVLFKKYNIPEPIVGGLIVAFFITILHFQGINLKFSLPLQSTFMLMFFSTV
GLAANYKQLIKGGSKVFIFLAVASVYIIIQNGIGVSLASLMGLDPLMGLIAGSITLSGGHGTGAAWSHTFAETYHLNTLE
LAMASATFGLIMGGLIGSPIAQKLIHKHNLESEYGTGIDTHSRFPEVVTYNEREEEKVTAKKVIETLFVLLLCVVGAGHL
GDFIATFDIAWLKIPDFVYALFIGVFITNITEVTKVHKIDTETVDILGTVSLALFLAMALMSLKLWNIFDLAIPLLIILS
IQTVVLALFSYFVTFRVMGSNYDAAVMAGGHCGFGLGATPTAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDIVNLIILQ
TYISFIG

Sequences:

>Translated_407_residues
MSHTLSIGALESFLIAIAVLFLGHLINSKVVLFKKYNIPEPIVGGLIVAFFITILHFQGINLKFSLPLQSTFMLMFFSTV
GLAANYKQLIKGGSKVFIFLAVASVYIIIQNGIGVSLASLMGLDPLMGLIAGSITLSGGHGTGAAWSHTFAETYHLNTLE
LAMASATFGLIMGGLIGSPIAQKLIHKHNLESEYGTGIDTHSRFPEVVTYNEREEEKVTAKKVIETLFVLLLCVVGAGHL
GDFIATFDIAWLKIPDFVYALFIGVFITNITEVTKVHKIDTETVDILGTVSLALFLAMALMSLKLWNIFDLAIPLLIILS
IQTVVLALFSYFVTFRVMGSNYDAAVMAGGHCGFGLGATPTAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDIVNLIILQ
TYISFIG
>Mature_406_residues
SHTLSIGALESFLIAIAVLFLGHLINSKVVLFKKYNIPEPIVGGLIVAFFITILHFQGINLKFSLPLQSTFMLMFFSTVG
LAANYKQLIKGGSKVFIFLAVASVYIIIQNGIGVSLASLMGLDPLMGLIAGSITLSGGHGTGAAWSHTFAETYHLNTLEL
AMASATFGLIMGGLIGSPIAQKLIHKHNLESEYGTGIDTHSRFPEVVTYNEREEEKVTAKKVIETLFVLLLCVVGAGHLG
DFIATFDIAWLKIPDFVYALFIGVFITNITEVTKVHKIDTETVDILGTVSLALFLAMALMSLKLWNIFDLAIPLLIILSI
QTVVLALFSYFVTFRVMGSNYDAAVMAGGHCGFGLGATPTAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDIVNLIILQT
YISFIG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=385, Percent_Identity=48.8311688311688, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43928; Mature: 43797

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTLSIGALESFLIAIAVLFLGHLINSKVVLFKKYNIPEPIVGGLIVAFFITILHFQGI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
NLKFSLPLQSTFMLMFFSTVGLAANYKQLIKGGSKVFIFLAVASVYIIIQNGIGVSLASL
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHH
MGLDPLMGLIAGSITLSGGHGTGAAWSHTFAETYHLNTLELAMASATFGLIMGGLIGSPI
HCHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHH
AQKLIHKHNLESEYGTGIDTHSRFPEVVTYNEREEEKVTAKKVIETLFVLLLCVVGAGHL
HHHHHHHHCCCHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
GDFIATFDIAWLKIPDFVYALFIGVFITNITEVTKVHKIDTETVDILGTVSLALFLAMAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MSLKLWNIFDLAIPLLIILSIQTVVLALFSYFVTFRVMGSNYDAAVMAGGHCGFGLGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
TAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDIVNLIILQTYISFIG
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SHTLSIGALESFLIAIAVLFLGHLINSKVVLFKKYNIPEPIVGGLIVAFFITILHFQGI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
NLKFSLPLQSTFMLMFFSTVGLAANYKQLIKGGSKVFIFLAVASVYIIIQNGIGVSLASL
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHH
MGLDPLMGLIAGSITLSGGHGTGAAWSHTFAETYHLNTLELAMASATFGLIMGGLIGSPI
HCHHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHH
AQKLIHKHNLESEYGTGIDTHSRFPEVVTYNEREEEKVTAKKVIETLFVLLLCVVGAGHL
HHHHHHHHCCCHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
GDFIATFDIAWLKIPDFVYALFIGVFITNITEVTKVHKIDTETVDILGTVSLALFLAMAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MSLKLWNIFDLAIPLLIILSIQTVVLALFSYFVTFRVMGSNYDAAVMAGGHCGFGLGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
TAVMNMGSLVSRFGPSPQAFMVVPIVGAFFIDIVNLIILQTYISFIG
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]