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The map label for this gene is glnP [H]

Identifier: 59713575

GI number: 59713575

Start: 444041

End: 444835

Strand: Reverse

Name: glnP [H]

Synonym: VF_A0392

Alternate gene names: 59713575

Gene position: 444835-444041 (Counterclockwise)

Preceding gene: 59713576

Following gene: 59713574

Centisome position: 33.44

GC content: 37.23

Gene sequence:

>795_bases
ATGAATTACTTTACTCGTATTTTTGCACCAGTTCTCTCTGCAACTCTTCAGATCGTATTACTTAGTTTAGGTCTTTTTTG
GGTTTTGGACAGTGGTGCTCAAGCCATGAACTATCAATGGCAATGGGATCGAGTTCCTGACTTCATTTTCTTTTATGAAG
ATGGGGAATGGTTTCCTGCAGAACTAATTGAAGGTTTGTTGGTTACTTTACAAATATCCGCCATCAGTGCGATTGCAACA
CTTGCTATTGCTCTGGTAACTGCATTATTGCGCCTATCAAACTCTATTGTAGGTAAAACAATATCAACGCTATACATTGA
GTTGATCCGTAATACCCCATTATTGGTTCAAATCTATTTATTGTATTTCGTTTTTGGTCCTTTTTTAGGCTTAGAGCGTT
TCACTACTGCCGTCTTAGCTTTAGCTTTGTTTCAAGGAGCATATACAGCCGAAATCTTACGTTCAGGTTTAATCAATCTA
CCTAAAGGGCAATTTGAGGCGTGTAAGACATTAGGACTTTCTCAATTCAATAGCTATCGATATGTTGTTTTACCTCAAGT
AATTAGAAAAACCTTACCCTCACTAACCAACGAATTAGTTTCCTTAGTTAAAAACTCTTCTATAGTCAGTGTAATGGCTA
TTTTTGACCTTACTACTGAGGGAAGAAATATTGTATCGGATACAGCCATGCCATTTGAAATTTGGTTTACAGTGGCCGCC
ATCTATTTAATGATTACATTAAGCCTTTCTGCTTTATCAGCATGGCTAGAATACAGAATGCACAACGCACACTAA

Upstream 100 bases:

>100_bases
GAAGGTGAAATTGTTGAGATTGCAGAGCCTCTCCAGTTTTTTGAATCCCCACAACACACTCGAACTCAACGCTTTTTAAA
CCAAATATTAAGCTATTAAG

Downstream 100 bases:

>100_bases
GGAGAACAACTCGCATGAAGCACCTATTACTTTCGTTTTTTGGATTAAGTTTACTATTTAGTAGTTCAGCATTTTCCGCA
ACGACAATCGACAGCACACC

Product: amino acid ABC transporter permease protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNYFTRIFAPVLSATLQIVLLSLGLFWVLDSGAQAMNYQWQWDRVPDFIFFYEDGEWFPAELIEGLLVTLQISAISAIAT
LAIALVTALLRLSNSIVGKTISTLYIELIRNTPLLVQIYLLYFVFGPFLGLERFTTAVLALALFQGAYTAEILRSGLINL
PKGQFEACKTLGLSQFNSYRYVVLPQVIRKTLPSLTNELVSLVKNSSIVSVMAIFDLTTEGRNIVSDTAMPFEIWFTVAA
IYLMITLSLSALSAWLEYRMHNAH

Sequences:

>Translated_264_residues
MNYFTRIFAPVLSATLQIVLLSLGLFWVLDSGAQAMNYQWQWDRVPDFIFFYEDGEWFPAELIEGLLVTLQISAISAIAT
LAIALVTALLRLSNSIVGKTISTLYIELIRNTPLLVQIYLLYFVFGPFLGLERFTTAVLALALFQGAYTAEILRSGLINL
PKGQFEACKTLGLSQFNSYRYVVLPQVIRKTLPSLTNELVSLVKNSSIVSVMAIFDLTTEGRNIVSDTAMPFEIWFTVAA
IYLMITLSLSALSAWLEYRMHNAH
>Mature_264_residues
MNYFTRIFAPVLSATLQIVLLSLGLFWVLDSGAQAMNYQWQWDRVPDFIFFYEDGEWFPAELIEGLLVTLQISAISAIAT
LAIALVTALLRLSNSIVGKTISTLYIELIRNTPLLVQIYLLYFVFGPFLGLERFTTAVLALALFQGAYTAEILRSGLINL
PKGQFEACKTLGLSQFNSYRYVVLPQVIRKTLPSLTNELVSLVKNSSIVSVMAIFDLTTEGRNIVSDTAMPFEIWFTVAA
IYLMITLSLSALSAWLEYRMHNAH

Specific function: Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=37.2549019607843, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082239, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788226, Length=204, Percent_Identity=30.3921568627451, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786874, Length=197, Percent_Identity=29.4416243654822, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786873, Length=207, Percent_Identity=27.0531400966184, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787087, Length=202, Percent_Identity=32.1782178217822, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788645, Length=218, Percent_Identity=27.9816513761468, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788646, Length=216, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787086, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994930, Length=115, Percent_Identity=33.9130434782609, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29628; Mature: 29628

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFTRIFAPVLSATLQIVLLSLGLFWVLDSGAQAMNYQWQWDRVPDFIFFYEDGEWFPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEECCCCCCEEEEEECCCCCHH
ELIEGLLVTLQISAISAIATLAIALVTALLRLSNSIVGKTISTLYIELIRNTPLLVQIYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LYFVFGPFLGLERFTTAVLALALFQGAYTAEILRSGLINLPKGQFEACKTLGLSQFNSYR
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHCCCE
YVVLPQVIRKTLPSLTNELVSLVKNSSIVSVMAIFDLTTEGRNIVSDTAMPFEIWFTVAA
EEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHH
IYLMITLSLSALSAWLEYRMHNAH
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNYFTRIFAPVLSATLQIVLLSLGLFWVLDSGAQAMNYQWQWDRVPDFIFFYEDGEWFPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEECCCCCCEEEEEECCCCCHH
ELIEGLLVTLQISAISAIATLAIALVTALLRLSNSIVGKTISTLYIELIRNTPLLVQIYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LYFVFGPFLGLERFTTAVLALALFQGAYTAEILRSGLINLPKGQFEACKTLGLSQFNSYR
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHCCCE
YVVLPQVIRKTLPSLTNELVSLVKNSSIVSVMAIFDLTTEGRNIVSDTAMPFEIWFTVAA
EEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHH
IYLMITLSLSALSAWLEYRMHNAH
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]