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The map label for this gene is 59713270

Identifier: 59713270

GI number: 59713270

Start: 95069

End: 96136

Strand: Reverse

Name: 59713270

Synonym: VF_A0087

Alternate gene names: NA

Gene position: 96136-95069 (Counterclockwise)

Preceding gene: 59713273

Following gene: 59713269

Centisome position: 7.23

GC content: 38.76

Gene sequence:

>1068_bases
ATGAAAAAAGAACGTACTTTGATTATCAATAAAAAGATCGCTTTAATAGGAGTTACCGTCATGGCTTTCACTTTTTCTTA
TTTCCAACAAGGTGAGAAGGATTCCCAAGCTCGTTTTAAAAACAGCGAGATGGAATACACGACCAGTACAAGTAATATTT
GGGATATCGCTAAAGCATACATTTCAACCACAAGAGTTGAGGCGACACCTAAAAATACAGTACCTGTTCAAGCCATTTCT
ATTGATGATTTAATGCAAGAAAAAGAAGCCGTGCTATATCGCCTTGGACATTCCTCTGTTTTGATCAAACTTGACGGTCA
ACTTATCTTAACTGATCCTGTTTTTAGTGATCGCGCTTCACCTGTTCAATGGGCGGGGCCAAAACGTTTTCATGCTGCGC
CTATCTCAATTTCTGATCTCCCAACAATTCAAGTGGTTGCTATTAGCCATGACCATTATGATCATCTCGATAAGCATGCA
GTAAAACAGTTAAACGATAAAGTAGAGCACTTTGTCGTTCCTCTTCGTGTTGGGAAATTACTCAAAAAATGGGGTGTAGA
AGAAAATAAGATCACCGAGTTTGATTGGTGGCAATCTCATACGATTAGTCATATTGAATTCTCTTTTGCACCGACCCAAC
ATTTCTCAGGTCGTGGTTTAACAGATAAAAACAGCACGTTATGGGGAAGTTGGGTCATCAAAGGCAAGCAAGCAAACCTT
TTCTTTAGTGGCGACTCTGGTTATTTTTCTGGATTTAAAGAGATCGGCGATAAATACGGTCCATTTGACTTAACGATGGT
TGAAACTGGCGCATATAATGAATTATGGTCAGATATTCATATGTTCCCATCACAAAGTGTACAAGCACATTTAGATGTTA
AAGGACAAACTATGATGCCAATTCATAATAGTACGTTTGATTTAGCCCTGCACGATTGGCAAGATCCTCTAGAACAGGTA
TCTGCTATTAGTGCCGAAAAAAAAGTACGTTTAGTCACCCCAATTATTGGAGAGAAAATCATGATCACAGACCCAAAAGT
AACATCTCATTGGTGGCGTGAAATGTAA

Upstream 100 bases:

>100_bases
TCCTCGTAAGGAAAACGACGAAATAAGGAAAATTAGCTACTCTAATACCAATCACAGTAAGAAAGTGTTTAGACATGACG
AGTGGTTAAAAGGGATAAAT

Downstream 100 bases:

>100_bases
CTTAACTTCATAAAGCACAACATTGAGAGTGAATGACTCACTCTCAATTCGTTTAAAATGTGAGCATCAACCAAGAACCA
TAATAAGCTATTCGACACTC

Product: outer membrane protein RomA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKKERTLIINKKIALIGVTVMAFTFSYFQQGEKDSQARFKNSEMEYTTSTSNIWDIAKAYISTTRVEATPKNTVPVQAIS
IDDLMQEKEAVLYRLGHSSVLIKLDGQLILTDPVFSDRASPVQWAGPKRFHAAPISISDLPTIQVVAISHDHYDHLDKHA
VKQLNDKVEHFVVPLRVGKLLKKWGVEENKITEFDWWQSHTISHIEFSFAPTQHFSGRGLTDKNSTLWGSWVIKGKQANL
FFSGDSGYFSGFKEIGDKYGPFDLTMVETGAYNELWSDIHMFPSQSVQAHLDVKGQTMMPIHNSTFDLALHDWQDPLEQV
SAISAEKKVRLVTPIIGEKIMITDPKVTSHWWREM

Sequences:

>Translated_355_residues
MKKERTLIINKKIALIGVTVMAFTFSYFQQGEKDSQARFKNSEMEYTTSTSNIWDIAKAYISTTRVEATPKNTVPVQAIS
IDDLMQEKEAVLYRLGHSSVLIKLDGQLILTDPVFSDRASPVQWAGPKRFHAAPISISDLPTIQVVAISHDHYDHLDKHA
VKQLNDKVEHFVVPLRVGKLLKKWGVEENKITEFDWWQSHTISHIEFSFAPTQHFSGRGLTDKNSTLWGSWVIKGKQANL
FFSGDSGYFSGFKEIGDKYGPFDLTMVETGAYNELWSDIHMFPSQSVQAHLDVKGQTMMPIHNSTFDLALHDWQDPLEQV
SAISAEKKVRLVTPIIGEKIMITDPKVTSHWWREM
>Mature_355_residues
MKKERTLIINKKIALIGVTVMAFTFSYFQQGEKDSQARFKNSEMEYTTSTSNIWDIAKAYISTTRVEATPKNTVPVQAIS
IDDLMQEKEAVLYRLGHSSVLIKLDGQLILTDPVFSDRASPVQWAGPKRFHAAPISISDLPTIQVVAISHDHYDHLDKHA
VKQLNDKVEHFVVPLRVGKLLKKWGVEENKITEFDWWQSHTISHIEFSFAPTQHFSGRGLTDKNSTLWGSWVIKGKQANL
FFSGDSGYFSGFKEIGDKYGPFDLTMVETGAYNELWSDIHMFPSQSVQAHLDVKGQTMMPIHNSTFDLALHDWQDPLEQV
SAISAEKKVRLVTPIIGEKIMITDPKVTSHWWREM

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=230, Percent_Identity=42.6086956521739, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI170932481, Length=230, Percent_Identity=42.6086956521739, Blast_Score=201, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI17543104, Length=285, Percent_Identity=36.8421052631579, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17543102, Length=249, Percent_Identity=35.3413654618474, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17543100, Length=249, Percent_Identity=35.3413654618474, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25148824, Length=249, Percent_Identity=35.3413654618474, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6325154, Length=297, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40395; Mature: 40395

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKERTLIINKKIALIGVTVMAFTFSYFQQGEKDSQARFKNSEMEYTTSTSNIWDIAKAY
CCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCHHHHHHHHH
ISTTRVEATPKNTVPVQAISIDDLMQEKEAVLYRLGHSSVLIKLDGQLILTDPVFSDRAS
HHHHEEECCCCCCCCEEEECHHHHHHHHHHHHEEECCCEEEEEECCEEEEECCCCCCCCC
PVQWAGPKRFHAAPISISDLPTIQVVAISHDHYDHLDKHAVKQLNDKVEHFVVPLRVGKL
CCCCCCCCCEEECCCEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHEEHHHHHHHH
LKKWGVEENKITEFDWWQSHTISHIEFSFAPTQHFSGRGLTDKNSTLWGSWVIKGKQANL
HHHHCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCEEE
FFSGDSGYFSGFKEIGDKYGPFDLTMVETGAYNELWSDIHMFPSQSVQAHLDVKGQTMMP
EEECCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCEEEC
IHNSTFDLALHDWQDPLEQVSAISAEKKVRLVTPIIGEKIMITDPKVTSHWWREM
CCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECHHHCCEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MKKERTLIINKKIALIGVTVMAFTFSYFQQGEKDSQARFKNSEMEYTTSTSNIWDIAKAY
CCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCHHHHHHHHH
ISTTRVEATPKNTVPVQAISIDDLMQEKEAVLYRLGHSSVLIKLDGQLILTDPVFSDRAS
HHHHEEECCCCCCCCEEEECHHHHHHHHHHHHEEECCCEEEEEECCEEEEECCCCCCCCC
PVQWAGPKRFHAAPISISDLPTIQVVAISHDHYDHLDKHAVKQLNDKVEHFVVPLRVGKL
CCCCCCCCCEEECCCEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHEEHHHHHHHH
LKKWGVEENKITEFDWWQSHTISHIEFSFAPTQHFSGRGLTDKNSTLWGSWVIKGKQANL
HHHHCCCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCEEE
FFSGDSGYFSGFKEIGDKYGPFDLTMVETGAYNELWSDIHMFPSQSVQAHLDVKGQTMMP
EEECCCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCEEEC
IHNSTFDLALHDWQDPLEQVSAISAEKKVRLVTPIIGEKIMITDPKVTSHWWREM
CCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECHHHCCEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]